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Blood Coagulation Mechanism and Endotoxins: Hemostatic Defect in Septic Shock

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Gram-Negative Bacterial Infections and Mode of Endotoxin Actions

Abstract

The effect of endotoxins and bacterial toxins on the blood clotting system has been clearly demonstrated by means of the Sanarelli-Shwartzman phenomenon in the animal experiment (1, 2). The involvement of diffuse intravascular coagulation as the essential pathophysiological event is of decisive implication for the pathomorphological picture as well as for the course of the syndrome.

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References

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Authors
  1. D. L. Heene
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Editors and Affiliations

  1. Abteilung für Immunologie und Serologie am Institut für Hygiene und Medizinische Mikrobiologie der Fakultät für Klinische Medizin Mannheim, Universität Heidelberg, Mannheim, Federal Republic of Germany

    Bernhard Urbaschek  & Renate Urbaschek  & 

  2. Departments of Microbiology and Pediatrics, State University of New York at Buffalo, Buffalo, N.Y., USA

    Erwin Neter M. D.

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© 1975 Springer-Verlag/Wien

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Heene, D.L. (1975). Blood Coagulation Mechanism and Endotoxins: Hemostatic Defect in Septic Shock. In: Urbaschek, B., Urbaschek, R., Neter, E. (eds) Gram-Negative Bacterial Infections and Mode of Endotoxin Actions. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8396-0_48

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  • DOI: https://doi.org/10.1007/978-3-7091-8396-0_48

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8398-4

  • Online ISBN: 978-3-7091-8396-0

  • eBook Packages: Springer Book Archive

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