Abstract
Endotoxic lipopolysaccharides (LPS) are known to interact with the complement system. This interaction, leading to the activation of C3, takes place in normal as well as in C4-deficient guinea pig serum and thus represents an example for the alternate pathway of C activation starting with C3. This does not exclude the activation of Cl, C4 and C2 provided a LPS-specific antibody is available.
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© 1975 Springer-Verlag/Wien
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Bitter-Suermann, D., Hadding, U. (1975). Influence of Lipid A and Various LPS-Preparations on the Third Component of Complement (C 3): Biological Significance of this Interaction. In: Urbaschek, B., Urbaschek, R., Neter, E. (eds) Gram-Negative Bacterial Infections and Mode of Endotoxin Actions. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8396-0_43
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DOI: https://doi.org/10.1007/978-3-7091-8396-0_43
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-8398-4
Online ISBN: 978-3-7091-8396-0
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