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Serum Lipids in Experimental Consumption Coagulopathy Induced by Endotoxin and Thorotrast

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Gram-Negative Bacterial Infections and Mode of Endotoxin Actions

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Abstract

The generalized Shwartzman reaction is identified by glomerular capillary thrombi and bilateral renal cortical necrosis (7). The reaction is the result of two intravenous injections of endotoxin spaced 24 hours apart. The first injection of endotoxin can be substituted by the intravenous administration of thorotrast. Impairment of the reticulo-endothelial system by thorotrast is suggested to be the pathogenic pathway in the production of the Sanarelli-Shwartzman phenomenon after the preparative injection of thorotrast (1, 3).

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Authors
  1. K. Nekarda
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  2. K. Huth
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  3. F. W. Schmahl
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  4. G. Müller-Berghaus
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Editors and Affiliations

  1. Abteilung für Immunologie und Serologie am Institut für Hygiene und Medizinische Mikrobiologie der Fakultät für Klinische Medizin Mannheim, Universität Heidelberg, Mannheim, Federal Republic of Germany

    Bernhard Urbaschek  & Renate Urbaschek  & 

  2. Departments of Microbiology and Pediatrics, State University of New York at Buffalo, Buffalo, N.Y., USA

    Erwin Neter M. D.

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© 1975 Springer-Verlag/Wien

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Nekarda, K., Huth, K., Schmahl, F.W., Müller-Berghaus, G. (1975). Serum Lipids in Experimental Consumption Coagulopathy Induced by Endotoxin and Thorotrast. In: Urbaschek, B., Urbaschek, R., Neter, E. (eds) Gram-Negative Bacterial Infections and Mode of Endotoxin Actions. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8396-0_37

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  • DOI: https://doi.org/10.1007/978-3-7091-8396-0_37

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8398-4

  • Online ISBN: 978-3-7091-8396-0

  • eBook Packages: Springer Book Archive

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