Skip to main content
SpringerLink
Log in

Assessment of Studies in the Biochemistry and Immunology of Endotoxemia

  • Chapter
Gram-Negative Bacterial Infections and Mode of Endotoxin Actions

  • 156 Accesses

Abstract

For the past four years, we have been engaged in the study of the biochemistry and immunology of endotoxemia according to the experimental model shown in Fig. 1. We studied the effect of steroids on the complexing of complement, antibody, and lipopolysaccharide (LPS) in endotoxemia. This led us to study the action of chemical mediators during this immune reaction. Finally, we decided to investigate the metabolic changes during the hypovolemic phase of endotoxic shock.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Vick, J.A., Mehman, B., Heiffer, M.H.: Proc. Soc. exp. Biol. Med. 137: 902 (1971).

    CAS  Google Scholar 

  2. Schumer, W.: Histamine release in endotoxin shock: Effect of dexamethasone administration. In: Hinshaw, L. B., Cox, B. G.: The Fundamental Mechanisms of Shock. ( Plenum Publishing Corporation,New York 1972 ).

    Google Scholar 

  3. Lichtenstein, L. M., Gewurz, H., Adkinson, N. F. Jr., Shin, H. S., Mergenhagen, S. E.: Immunology 16: 327 (1969).

    PubMed  CAS  Google Scholar 

  4. Dias da Silva, W., Lepow, I.H.: J. exp. Med. 125: 921 (1967).

    Article  Google Scholar 

  5. Orange, R.P., Austen, K. F.: Hosp. Pract. 6: 79 (1971).

    Google Scholar 

  6. Lalloue, K. F., Mason, A. D., Daniels, J.P.: Metabolism 17: 606 (1968).

    Article  Google Scholar 

  7. Berry, L. J., Smythe, D.S.: J. exp. Med. 120: 721 (1964).

    Article  PubMed  CAS  Google Scholar 

  8. Williamson, J.R., Refino, C., Lalloue, K.: Effects of E. coli lipopolysaccharide B treatment of rats on gluconeogenesis. In: Porter, R., Knight, J.: Energy Metabolism in Trauma. A Ciba Symposium. ( Churchill, London 1970 ).

    Google Scholar 

Download references

Authors
  1. W. Schumer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung für Immunologie und Serologie am Institut für Hygiene und Medizinische Mikrobiologie der Fakultät für Klinische Medizin Mannheim, Universität Heidelberg, Mannheim, Federal Republic of Germany

    Bernhard Urbaschek  & Renate Urbaschek  & 

  2. Departments of Microbiology and Pediatrics, State University of New York at Buffalo, Buffalo, N.Y., USA

    Erwin Neter M. D.

Rights and permissions

Reprints and permissions

Copyright information

© 1975 Springer-Verlag/Wien

About this chapter

Cite this chapter

Schumer, W. (1975). Assessment of Studies in the Biochemistry and Immunology of Endotoxemia. In: Urbaschek, B., Urbaschek, R., Neter, E. (eds) Gram-Negative Bacterial Infections and Mode of Endotoxin Actions. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8396-0_34

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-8396-0_34

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8398-4

  • Online ISBN: 978-3-7091-8396-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation