Function of Leukocytes in Defense Mechanisms

  • J. W. Alexander


Neutrophils have been recognized as an essential component of host defense against infection since Metchinkoff’s pioneering work at the turn of the century (1). However, critical examination of this important cell was not made until recently when renewed interest in host defense mechanisms was stimulated by a distressing awareness that sepsis continued to be one of the leading causes of morbidity and mortality. Also, increasing numbers of antibiotic resistant pathogens were emerging in both nosocomial and community environments.


Positive Blood Culture Neutrophil Function Longe Cycle NADH Oxidase Activity Antibacterial Function 
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© Springer-Verlag/Wien 1975

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  • J. W. Alexander

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