The Mitogenic Activity of Lipopolysaccharides on Lymphocytes in Culture

II. Comparative Study in Five Mammalian Species
  • C. Bona
  • C. Damais
  • C. Galanos
  • L. Chedid


The administration of bacterial endotoxins to mammalian species produces various pathologic, physiologic and immunologic effects include leukocytosis, fever, the Shwartzman reaction, increase of the background of immune response against various antigens (polyclonal stimulation of B-derived lymphocytes), release of endogenous pyrogens, and death.


Mouse Lymph Node Mouse Spleen Small Lymphocyte Mouse Spleen Cell Human Blood Lymphocyte 
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© Springer-Verlag/Wien 1975

Authors and Affiliations

  • C. Bona
  • C. Damais
  • C. Galanos
  • L. Chedid

There are no affiliations available

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