Transformation of Mouse B-Lymphocytes by the Lipid Component of Endotoxin

  • S. E. Mergenhagen
  • D. L. Rosenstreich
  • A. Nowotny
  • T. Chused


Several investigators have suggested that there is an immunological basis for certain of the biological activities associated with endotoxin reactions. This is based upon a number of recent studies which have shown that endotoxic lipopolysaccharides (LPS), like immune complexes, are effective in activating humoral effector systems such as complement and coagulation, and are mitogenic for lymphoid cells.


Spleen Cell Tritiated Thymidine Lipid Moiety Lipid Preparation Cobra Venom Factor 


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Copyright information

© Springer-Verlag/Wien 1975

Authors and Affiliations

  • S. E. Mergenhagen
  • D. L. Rosenstreich
  • A. Nowotny
  • T. Chused

There are no affiliations available

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