Regulation Mechanisms of Central and Peripheral Sympathetic Neurons

  • G. Hertting
  • B. Peskar
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 12)


For many years, the main interest in mechanisms regulating the activity of peripheral sympathetic neurons has been focussed on the structures which maintain the homoeostasis of blood circulation or adapt the circulation to the momentary needs. The mechanisms for this type of regulation receive their information through pressor-, chemo- or volume receptors. This information is then integrated in central structures, and the efferent impulses adapt the periphery to the specific situation. The peripheral activity of the sympathetic nervous system, however, can in addition be modified by local processes that adjust their activity and function to local needs which had escaped being monitored because they were too specialized to be regulated by an overall adjustment, or even apparently controversial to it. In the last decade the knowledge about these local mechanisms has increased, and some of them will be briefly discussed in this paper.


Sympathetic Nerve Transmitter Release Rabbit Heart Acta Physiol Sympathetic Nerve Terminal 
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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • G. Hertting
    • 1
  • B. Peskar
    • 1
  1. 1.Department of PharmacologyUniversity of Freiburg i. Br.Freiburg i. Br.Federal Republic of Germany

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