Stereotactic Hypothalamotomy in Erethic Children

  • V. E. Arjona
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 21)


It is possible to control aggressive behaviour by surgical means. A fair number of operations, mainly stereotactic, have been reported aiming to produce lesions in structures related to emotional pathways and a high rate of success has been claimed by several authors. These operations include frontal leucotomy (Freeman and Watts 1950), lesions in the orbital cortex (Scoville 1951, Knight 1964), dorsomedian thalamotomy (Spiegel et al. 1949), amygdalotomy (Narabayashi 1961, Narabayashi et al. 1963, Heimburger et al. 1966, Vaernet and Madsen 1970), cingulectomy (Lebeau 1952, Lebeau 1954, Sano 1954, Ballantine et al. 1967), anterior thalamotomy (Spiegel and Wycis 1953, Handa et al. 1961), fornicotomy (Sano 1957) etc.


Aggressive Behaviour Mental Retardation Lateral Hypothalamus Spastic Paraparesis Intractable Pain 
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  1. 1.
    Ballantine, H. T., Cassidy, W. L., Flanigan, N. B., Marino, R. (1967), Stereotaxic anterior cingulotomy for neuropsychiatrie illness and intractable pain. J. Neurosurg. 26, 488–495.PubMedCrossRefGoogle Scholar
  2. 2.
    Bard, P. (1939), Central nervous mechanisms for emotional behaviour patterns on animals. Research Publications, Association for Research in Nervous and Mental Disease 19, 190–218.Google Scholar
  3. 3.
    Beattie, J. (1932), Hypothalamic mechanisms. Canad. med. Ass. J. 26, 400–405.Google Scholar
  4. 4.
    Beattie, J. Brow, C. R., Long, C. N. H. (1930), Physiological and anatomical evidence for the existence of nerve tracts connecting the hypothalamus with spinal sympathetic centres. Proc. Roy. Soc. 106, 253–275.CrossRefGoogle Scholar
  5. 5.
    Cooper, I. S., Grissrnan, F., Johnston, R. (1962), A complete system for cryogenic surgery. St. Barnabas Hosp. Med. Bull. 1,11–19.Google Scholar
  6. 6.
    Cooper, I. S. (1963), Cryogenic Surgery. New Eng. J. Med. 268, 743–756.CrossRefGoogle Scholar
  7. 7.
    Freeman, W., Watts, J. W. (1950), Psychosurgery in the treatment of mental disorders and intractable pain. 2nd. Ed. Springfield, Ill.: Ch. C Thomas.Google Scholar
  8. 8.
    Handa, H., Mori, K., Yoshida, K., Stereoencephalotomy in agitated idiocy (cited by Sano).Google Scholar
  9. 9.
    Heimburger, R. F., Whitlock, C. C., Kalsbeck, J. E. (1966), Stereotaxic amygdalotomy for epilepsy with aggressive behaviour. J. Amer. med. Ass. 198, 741–745.CrossRefGoogle Scholar
  10. 10.
    Hess, W. R. (1947), Vegetative Funktionen und Zwischenhirn. Hely. Physiol. Acta Suppl. I V.Google Scholar
  11. 11.
    Hess, W. R. (1969), Hypothalamus and thalamus: experimental documentation. Stuttgart: Thieme.Google Scholar
  12. 12.
    Ingram, W. R. (1952), Brain stem mechanisms in behaviour. EEG Clin. Neurophysiol. 4, 397–406.Google Scholar
  13. 13.
    Ingram, W. R. Knott, J. R., Wheatly, M. D., Summer, T. D. (1951), Physiological relationships between hypothalamus and cerebral cortex. EEG Clin. Neurophysiol. 3, 37–58.Google Scholar
  14. 14.
    Knight, G. (1964), The orbital cortex as an objective in the surgical treatment of mental illness. Brit. J. Surg. 51, 114–124.PubMedCrossRefGoogle Scholar
  15. 15.
    Kurotsu, T. (1954), Changes of finer structures of different gland cells indiced by the electrical stimulation of the hypothalamus. Med. J. Osaka Univ. 5, 87–104.Google Scholar
  16. 16.
    Lebeau, J. (1954), Anterior cingulectomy in man. J. Neurosurg. 11, 268–276.CrossRefGoogle Scholar
  17. 17.
    Leksell, L. (1949), A stereotaxic apparatus for intracerebral surgery. Acta Chir. Scand. 99, 229–233.Google Scholar
  18. 18.
    Leksell, L. (1971), Stereotaxis and radiosurgery. An operative system. Springfield, Ill.: Ch. C Thomas.Google Scholar
  19. 19.
    Narabayashi, H., Nagao, T., Saito, T.. Yoshida, M., Naghata, M. (1963), Stereotaxic amygdalotomy for behaviour disorders. Arch. Neurol. (Chic.) 9, 1–16.CrossRefGoogle Scholar
  20. 20.
    Sano, K. (1954), Cingulectomy in the treatment of agitated mental defectives. Brain and Nerve 6, 146–156.Google Scholar
  21. 21.
    Sano, K. (1957), Fornicotomy Fol. psychiat. neurol. Jap. Suppl. 5, 57–58.Google Scholar
  22. 22.
    Sano, K. (1962), Sedative neurosurgery with special reference to posteromedial hypothalamotomy. Neurol. med. chir. 4, 112 142.Google Scholar
  23. 23.
    Sano, K. (1966), Sedative Stereoencephalotomy: Fornicotomy, upper mes-encephalic reticulotomy and postero-medial hypothalamotomy. In: Progress in brain Research. 21 B Part B Clinical Studies. Ed.: Tokizane, T., Schade, J. P. Amsterdam: Elsevier.Google Scholar
  24. 24.
    Sano, K. Mayanagi, Y., Sekino, H., Ogashiwa, M., Ishijima, B. (1970), Results of stimulation and destruction of the posterior hypothalamus in man. J. Neurosurg. 33, 689–707.PubMedCrossRefGoogle Scholar
  25. 25.
    Schvarcz, J. R., Driollet, R., Rios, E., Betti, O. (1972), Stereotactic hypothalamotomy for behaviour disorders. J. Neurol. Neurosurg. Psychiat. 35, 356–359.PubMedCrossRefGoogle Scholar
  26. 26.
    Scoville, W. B. (1949), Selective cortical undercutting as means of modifying and studying frontal lobe functions in man. Preliminary report of 43 operative cases. J. Neurosurg. 6, 65–73.PubMedCrossRefGoogle Scholar
  27. 27.
    Spiegel, E. A., Wycis, H. T., Freed, H. (1949), Thalamotomy: neuropsychiatrie aspects. New York S. J. Med. 49, 2273–2274.Google Scholar
  28. 28.
    Spiegel, E. A., Wycis, H. T., Freed, H., Orchinik, C. (1953), Thalamotomy and hypothalamotomy for the treatment of psychoses. Ass. Res. Nerv. Ment. Dis. 31, 379–391.Google Scholar
  29. 29.
    Vaernet, K., Madsen, A. (1970), Stereotaxic amygdalotomy and baso-frontal tractotomy in psychotics with aggressive behaviour. J. Neurol. Neurosurg. Psychiat. 33, 858–863.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • V. E. Arjona
    • 1
    • 2
  1. 1.Departamento de NeurocirugiaCiudad Sanitaria “Virgen del Rocio”SevillaSpain
  2. 2.“Las Villas”SevillaSpain

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