The Role of Choline in Maintaining the Fine Structure of Nerve Terminals in the Superior Cervical Ganglion of Cat
The fine structure of synapses was studied in the cat superior cervical ganglion under various experimental conditions. The presence of choline in the performed experiments was found to play an essential role not only in maintaining the intraganglionic nerve transmission, but also in preserving the normal fine structure of presynaptic terminals. Results obtained shed more light on other aspects of the vesicle hypothesis elucidating one of the cellular mechanisms by which the disappearance of synaptic vesicles in stimulated cholinergic nerve terminals could be interpreted.
KeywordsSynaptic Vesicle Presynaptic Terminal Superior Cervical Ganglion Perfusion Fluid Choline Deficiency
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