Role of Short-Range Transmitters in Hypothalamic Activities
Ovariectomy produced a decrease of the hypothalamic catecholamine content which could be restored by estradiol. Local implantation of estradiol resulted in a significant rise of the catecholamine concentration in the basal and medial hypothalamus. Testosterone administration was ineffective. During lactation the catecholamine content of the hypothalamus was higher than in nonlactating females.
Bilateral lesions in the preoptic area produced a decrease of the catecholamine concentration in the median eminence and the estradiol administration did not induce increase in ovariectomized and preoptic lesioned rats. It is assumed that rostral afferentation to the median eminence is involved in the function of catecholaminergic neurons.
KeywordsMedian Eminence Ergot Alkaloid Preoptic Area Dopamine Concentration Catecholamine Concentration
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