Neuronal Correlates of the Visual Evoked Response and Disinhibition in the Visual Cortex during Flicker Stimulation

  • U. Kuhnt
Conference paper


The hypothesis was put forward more than 20 years ago that postsynaptic potentials (PSPs) might be the generators of the surface EEG (Bremer 1949, Chang and Kaada 1950, Eccles 1951). In the visual cortex, temporal relationships between the evoked response to a flash of light recorded from the surface (VEP) and extracellularly were reported (Fromm and Bond 1967, Dill et al. 1968). A close correspondence between evoked spike activity and the positive wave of the VEP was found as well as a marked reduction of the spike activity during the negative wave recorded from the surface. Different results from intracellular recordings to light stimulation were reported by Crutzfeldt et al. (1969). They found a correspondence between the positive wave of the VEP and the evoked inhibitory postsynaptic potential (IPSP). With electrical stimulation of the specific afferent pathway the relationship between the evoked cellular potential and the surface potential becomes clearer: here the negative wave of the VEP runs parallel with the evoked IPSP (Watanabe et al. 1966).


Visual Cortex Light Flash Light Stimulation Positive Wave Negative Wave 


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Copyright information

© Springer-Verlag/Wien 1972

Authors and Affiliations

  • U. Kuhnt
    • 1
  1. 1.Abteilung NeurobiologieMax-Planck-Institut für Biophysikalische ChemieGöttingenGermany

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