Skip to main content
SpringerLink
Log in

Mechanisms of Cortical Discharges in “Generalized” Epilepsies in Man

  • Conference paper
Synchronization of EEG Activity in Epilepsies

Abstract

The stereotaxic EEG investigations in man, performed with macro-multilead electrodes (macro-SEEG) and intended to facilitate possible surgical intervention in recalcitrant cases of epilepsy, are unable to provide decisive information concerning the mechanisms of discharge synchronization. Nevertheless, the simultaneous investigation of a large number of cortical and subcortical structures implicated in the epileptic process can furnish some indications as to the site of origin and mode of propagation of critical discharges. We shall thus present several of the findings which have emerged from such studies regarding the highly controversial issue of whether the bilateral synchrony of the so-called “generalized” epilepsies is primary or secondary.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bancaud, J.: Physiopathogenesis of generalized epilepsies of organic nature. In: Gastaut, H., et al. (eds.), The physiopathogenesis of the epilepsies, pp. 158–187. Springfield: Thomas. 1969.

    Google Scholar 

  • Bancaud, J.: Role du cortex cérébral dans les épilepsies « généralisées » d’origine organique. Apport des investigations stéréoélectroencéphalographiques (S.E.E.G.) â la discussion de la conception « centrencéphalique ». Presse Méd. 79, 669–673 (1971).

    PubMed  CAS  Google Scholar 

  • Bancaud, J. et J. Talairach: La stéréo-électro-encéphalographie dans l’épilepsie. Paris: Masson. 1965.

    Google Scholar 

  • Bancaud, J., A. Bonis, C. Schaub, G. Szikla, and P. Morel: Information neuro-physiopathologique apportée par l’investigation fonctionelle stéréotaxique dans les épilepsies. Rev. Neurol. 100, 81–86 (1963).

    Google Scholar 

  • Bennett, F. E., and F. A. Gibbs: Intracarotid and intravertebral metrazol in petit mal epilepsy. Electroenceph. clin. Neurophysiol. 4, 382 (1952).

    Google Scholar 

  • Crain, S. M.: Electrical activity of brain tissue developing in culture. In: Jasper, H., et al. (eds.), Basic mechanisms of the epilepsies. Boston: Little, Brown & Co. 1969.

    Google Scholar 

  • Echlin, F. A.: The supersensitivity of chronically isolated cerebral cortex as a mechanism in focal epilepsy. Electroenceph. clin. Neurophysiol. 11, 697–722 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Gastaut, H., H. Jasper, J. Bancaud, and A. Waltregny: The physiopathogenesis of the epilepsy. Springfield: Thomas. 1969.

    Google Scholar 

  • Gastaut, H. and N. Pinsard: Séméiologie clinique des crises épileptiques chez l’enfant. Vie méd. 48, 865–872 (1967).

    Google Scholar 

  • Gastaut, H., N. Pinsard and J. Roger: Séméiologie électro-encéphalographique des crises épileptiques chez l’enfant en fonction de l’âge. Vie méd. 48, 873–878 (1967).

    Google Scholar 

  • Guerrero-Figueroa, R., and A. Darros: Experimental petit mal in kittens. Arch. Neurol. 9, 297–306 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Ingvar, D. H.: Reproduction of the 3/sec spike and wave EEG pattern by subcortical stimulation in cats. Acta physiol. scand. 33, 137–150 (1955).

    Article  PubMed  CAS  Google Scholar 

  • Ingvar, D. H.: On the pathophysiology of the 3/sec spike and wave epilepsy. Electroenceph. clin. Neurophysiol. 11, 187 (1959).

    Google Scholar 

  • Jasper, H. H., A. A. Ward, and A. Pope (eds.), Basic mechanisms of the epilepsies. Boston: Little, Brown & Co. 1969.

    Google Scholar 

  • Kaada, B. R.: Somatomotor automatisms and electroencephalographic response to electrical stimulation of rhinencephalon or other structure in primate, cat and dog. Acta physiol. scand. 24, Suppl. 83 (1951).

    Google Scholar 

  • Kopeloff, N., J. R. Waitin, B. L. Pacella, and L. Kopeloff: The epileptogenic effect of subcortical alumina cream in the rhesus monkey. Electroenceph. clin. Neurophysiol. 1, 163–168 (1950).

    Article  Google Scholar 

  • Lennox, M. A., and F. Robinson: Cingulate-cerebellar mechanisms in the physiological pathogenesis of epilepsy. Electroenceph. clin. Neurophysiol. 3, 197–206 (1951).

    Article  PubMed  CAS  Google Scholar 

  • Marcus, E. M., and S. Jacobson: An experimental model of petit mal epilepsy: electrical and behavioral correlates of acute bilateral epileptogenic foci in monkey cerebral cortex. Electroenceph. clin. Neurophysiol. 27, 735 (1969).

    Google Scholar 

  • Marcus, E. M. and C. W. Watson: Bilateral “epileptogenic” foci in cat cerebral cortex: mechanisms of interaction in the intact, the bilateral cortical callosal and adiencephalic preparation. Electroenceph. clin. Neurophysiol. 17, 454 (1964).

    Google Scholar 

  • Naquet, R., E. Balzano, and M. Poncet: The light sensitive epilepsy of Papio papio topographic study of cortico subcortical electroencephalographic paroxysmal activity. Electroenceph. clin. Neurophysiol. 24, 289 (1968).

    PubMed  CAS  Google Scholar 

  • Penfield, W., and H. H. Jasper: Epilepsy and the functional anatomy of human brain. Boston: Little, Brown & Co. 1954.

    Google Scholar 

  • Petsche, H., P. Rappelsberger, and R. Trappl: Properties of cortical seizure potential fields. Electroenceph. clin. Neurophysiol. 29, 567–578 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Pollen, D. A., P. Perot, and K. H. Reid: Experimental bilateral wave and spike from thalamic stimulation in relation to level of arousal. Electroenceph. clin. Neurophysiol. 15, 1017–1028 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Ralston, B. L.: Cingulate epilepsy and secondary bilateral synchrony. Electroenceph. clin. Neurophysiol. 13, 591–598 (1961).

    Article  PubMed  CAS  Google Scholar 

  • C. Ajmone Marsan: Thalamic control of certain normal and abnormal cortical rhythms. Electroenceph. clin. Neurophysiol. 8, 559–582 (1956).

    Article  PubMed  CAS  Google Scholar 

  • Sager, O., V. Chivu, M. Moisanu et S. Basilesco: Le complexe pointe-onde obtenu chez les animaux décortiqués bilatéralement pendant l’accès convulsif métrazolique. 1. Int. Congr. Neurol. Sci. Bruxelles, 1957. Excerpta Medica, pp. 75–76.

    Google Scholar 

  • Sasaki, M.: The importance of subcortical nuclei in epileptic convulsion. Tohoku Med. 51, 1–13 (1955).

    Google Scholar 

  • Shimizu, K., S. Refsum, and F. A. Gibbs: Effect on the electrical activity of the brain of intra-arterially and intra-cerebrally injected convulsant and sedative drugs. Electroenceph. clin. Neurophysiol. 4, 141–146 (1952).

    Article  PubMed  CAS  Google Scholar 

  • Starzl, T. E., W. T. Niemer, M. Dell, and P. R. Forgrave: Cortical and subcortical activity in experimental seizures induced by metrazol. J. Neuro-path. exp. Neurol. 12, 262–276 (1953).

    CAS  Google Scholar 

  • Weir, B.: Spike wave from stimulation of reticular core. Arch. Neurol. 11, 209–218 (1964).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Unité de Recherches I. N. S. E. R. M., Paris, France

    J. Bancaud

Authors
  1. J. Bancaud
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Neurological Institute of the University of Vienna and Brain Research Institute of the Austrian Academy of Sciences, Austria

    H. Petsche

  2. Brain Research Institute, University of California, Los Angeles, USA

    Mary A. B. Brazier

Rights and permissions

Reprints and permissions

Copyright information

© 1972 Springer-Verlag/Wien

About this paper

Cite this paper

Bancaud, J. (1972). Mechanisms of Cortical Discharges in “Generalized” Epilepsies in Man. In: Petsche, H., Brazier, M.A.B. (eds) Synchronization of EEG Activity in Epilepsies. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8306-9_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-8306-9_23

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8308-3

  • Online ISBN: 978-3-7091-8306-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation