The natural host for herpes simplex virus is man, in whom the disease caused by this virus is generally mild, although it can cause certain severe infections that will be described later. However, introduction of herpes simplex virus into susceptible animals results in severe infection. Herpes simplex virus can be transmitted experimentally to rabbits, guinea pigs, mice, rats, hamsters (Wenner, 1944), cotton rats (Florman and Trader, 1947), chick embryos (Beveridge and Burnet, 1946), 1 day old chicks, and pigeons, geese and hedgehogs (Rem-Linger and Bailly, 1927; Nicolau, 1948; van Rooyen and Rhodes, 1948; Tokumaru and Scott, 1964).
KeywordsPeripheral Nerve Herpes Simplex Chick Embryo Chorioallantoic Membrane Pseudorabies Virus
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