In nature, man is constantly being infected with herpes simplex virus, and in most instances, individuals survive the diseases caused by this virus, diseases which are frequently subclinical. This is a natural immunization and such individuals usually possess high titers of virus-specific antibody. Thus, infectious herpes simplex virus is a good antigen and will produce relatively high amounts of antibody. This is further demonstrated by the fact that convalescent sera of laboratory animals inoculated with virus and that survive infection possess antibody against herpes simplex virus.
KeywordsHerpes Simplex Thymidine Kinase Rabies Virus Virulent Virus Pseudorabies Virus
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