• A. S. Kaplan
Part of the Virology Monographs book series (VIROLOGY, volume 5)


The herpes group consists of viruses which have been placed together on the basis of a number of distinguishing features that they share in common (Andrewes, 1962). All these viruses are relatively large, possess identical morphological characteristics, contain DNA, and are extremely sensitive to inactivation by ether; these viruses are also assembled within the nucleus of the host cell and induce the formation of eosinophilic intranuclear inclusions. The epidemiology of some of the best known viruses in this group (herpes simplex, pseudorabies, and B-virus) is also similar (Burnet et al., 1939). Herpes simplex virus exists in the latent state in man, the natural host for this virus, and becomes overt in individuals subject to some form of stress; this condition appears to be paralleled by pseudorabies virus in its natural host, swine and by B-virus in monkeys. In each instance, transmission of the virus to a susceptible host other than the natural one results usually in marked symptoms and death.


Host Cell Herpes Simplex Latent State Natural Host Susceptible Host 
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Copyright information

© Springer-Verlag/Wien 1969

Authors and Affiliations

  • A. S. Kaplan
    • 1
  1. 1.Department of Microbiology, Research LaboratoriesAlbert Einstein Medical CenterPhiladelphiaUSA

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