These are exciting times in the study of protein synthesis. We are beginning to gain some insight into the mechanism by which amino acids are assembled into the peptide chains of proteins and to achieve some understanding of the way in which information is transferred from nucleus to cytoplasm, there to be used in the construction of the many individual proteins of the cell. The flood of new information and insight concerning protein synthesis has in part come from elegant enzymology and biochemistry applied to the study of the process. In part, and in a large part, however, it has come from a better understanding of the structure of the cell and from improved methods for the separation of cytoplasm into its subcellular constituents. These studies have focused attention upon the microsomes as the engines of protein synthesis. This review will therefore first consider the microsomes—their general role in protein synthesis, their origin and their structure. We shall then go on to the biochemistry and enzymology of protein synthesis insofar as we understand it today. Work on animal tissues and on microbial cells, as well as on plant tissues has contributed to our knowledge of protein synthesis, and although this review is particularly directed toward an understandig of plants, it will be helpful to draw on work with other materials.


Protein Synthesis Ribonucleic Acid Microsomal Protein Soluble Ribose Nucleic Acid Label Amino Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



adenosine diphosphate


adenosine monophosphate


adenosine triphosphate


deoxyribonucleic acid


ribonucleic acid


trichloroacetic acid.


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© Wien Springer Verlag 1958

Authors and Affiliations

  • James Bonner
    • 1
  1. 1.PasadenaUSA

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