Advertisement

Abstract

Rauwolfia plants contain alkaloids and constitute one of the important series of drugs of vegetable origin. In recent years, Rauwolfia has been the subject of considerable scientific research, particularly for its applications in medicine. It is an important genus of the family Apocynaceae which is characterized by the presence of toxic alkaloids, cardiac glycosides, coumarins and other bitter principles, some of which possess therapeutic value. The most important species of this family which are used in therapy are: Holarrherta antidysenterica Wall (5, 6, 7, 48, 57, 92, 93), commonly known as “kurchi” in India, applied in cases of dysentery; Alstonia scholaris R. Br. (40, 41, 62a, 50) as an antipyretic (73), Apocynum androsaemifolium L. and A. cannabium L. (1, 100) as substitutes for digitalis and as combined tonic diuretics for the treatment of cardiac dropsy; Strophanthus courmontii Franch (61) and Str. kombé Oliv (97) used in cases of cardiac weakness etc.

Keywords

Infrared Spectrum Ergot Alkaloid Ultraviolet Spectrum Isophthalic Acid Indole Nucleus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Allport, N.L.: Chemistry and Pharmacy of Vegetable Drugs. London: Newnes, Ltd. 1943, p. 102.Google Scholar
  2. 2.
    Allport, N.L. and S.K. Crews: Spectrographic Absorption of Ergometrine in Relation to the British Pharmacopeia Color Test. Quart. J. Pharm. Pharmacol. 8, 447 (1935)Google Scholar
  3. 3.
    Bader, F. und H. Schwarz: Zur Konstitution des Serpentins. Helv. chim. Acta 35, 1594 (1952).Google Scholar
  4. 3 a.
    Bader, F. E.: Die Lage der Doppelbindung im Ring E des Alstonins. Hely. chim. Acta 36, 215 (1953)CrossRefGoogle Scholar
  5. 4.
    Barger, G. und C. Scholz: Über Yohimbin. Helv. chim. Acta 16, 1343 (1933)Google Scholar
  6. 4 a.
    Bein, H. J.: Zur Pharmakologie des Reserpins, eines neuen Alkaloides aus Rauwolfia serpentines BENTH. Experientia 9, 107 (1953).CrossRefGoogle Scholar
  7. 5.
    Bertho, A.: Kurchi-Alkaloide. II. Über die Gewinnung von Conessin und dessen Nebenbasen. Arch. Pharmaz. u. Ber. dtsch. pharmaz. Ges. 277, 237 (1939)CrossRefGoogle Scholar
  8. 6.
    Bertho, A.: Kurchi-Alkaloide. III. Über das wirksame Hauptalkaloid Conkurchin. Liebigs Ann. Chem. 555, 214 (1944).Google Scholar
  9. 7.
    Bertho, A.: Kurchi-Alkaloide. V. Über die Aminobasen Conkurchin und Holarrhimin. Ber. dtsch. chem. Ges. 80, 316 (1947)Google Scholar
  10. 8.
    Bhatia, B.B. and R.D. Kapur: Pharmacological Action of Alkaloids of R. serpentina BENTH. I. Neo-ajmaline and Iso-amaline J Indian med. Res. 32, 177 (1944).Google Scholar
  11. 9.
    Bose, S.: Rauwolfinine, the New Alkaloid of the Root of Rauwolfia serpentina BENTH. Science and Culture (India) 48, 98 (1952).Google Scholar
  12. 9.
    Bose, S.: Rauwolfinine, the New Alkaloid of the Root of Rauwolfia serpentina BENTH. Science and Culture (India) 48, 98 (1952).Google Scholar
  13. 10.
    Bose, S., Chakravarti, M.D.: A Note on the Pharmacological Action of Rauwolscine. Science and Culture (India) 7, 458 (1942).Google Scholar
  14. 11.
    Chatterjee(née Mookerjee), A. (in the original papers Nos. II-14, and 17: MoOKERJEE): The Alkaloid of Rauwolfia canescens LINN. I. J. Indian chem. Soc. 18, 33 (1941).Google Scholar
  15. 12.
    Chatterjee (née Mookerjee), A. (in the original papers Nos. II-14, and 17: MoOKERJEE): The Alkaloid of Rauwolfia canescens Lime. II. J. Indian chem. Soc. 18, 485 (1941).Google Scholar
  16. 13.
    Chatterjee(née Mookerjee), A. (in the original papers Nos. II-14, and 17: MoOKERJEE): The Alkaloid of Rauwolfia canescens LINN. III. Some Degradation Products of Rauwolscine. J. Indian chem. Soc. 20, 11 (1943).Google Scholar
  17. 14.
    Chatterjee(née Mookerjee), A. (in the original papers Nos. II-14, and 17: MoOKERJEE): The Alkaloid of Rauwolfia canescens LINN. IV. On the Constitution of Rauwolscine. J. Indian chem. Soc. 23, 6 (1946).Google Scholar
  18. 15.
    Chatterjee(née Mookerjee), A. (in the original papers Nos. II-14, and 17: MoOKERJEE): The Alkaloid of Rauwolfia canescens LINN. V. J. Indian chem. Soc. 28, 29 ( 1950.Google Scholar
  19. 16.
    Chatterjee, A. and A. Bhattacharya: On the Active Principles Isolated from the Leaves and Bark of Skimmia laureola HooK. Current Sci. (India) 16, 222 (1947).Google Scholar
  20. 17.
    Chatterjee, A. and P.K. Bose: On the Constitution of the Alkaloid Isolated from the Bark of Chloroxylon swietenia D. C. J. Indian chem. Soc. 23, 1 (1946).Google Scholar
  21. 18.
    Chatterjee, A. and S. Bose: Rauwolfinine, the New Alkaloid from the Root of Rauwolfia serpentina BENTH. Science and Culture (India) 17, 139 (1951).Google Scholar
  22. 19.
    Chatterjee, A. and S. Bose: Studies on the Active Principles Isolated from the Leaves of Aegis marmelos CORREA. J. Indian chem. Soc. 29, 425 (1952).Google Scholar
  23. 19.
    Chatterjee, A. and S. Bose: Studies on the Active Principles Isolated from the Leaves of Aegis marmelos CORREA. J. Indian chem. Soc. 29, 425 (1952).Google Scholar
  24. 19.
    Chatterjee, A. and S. Bose: Studies on the Active Principles Isolated from the Leaves of Aegis marmelos CORREA. J. Indian chem. Soc. 29, 425 (1952).Google Scholar
  25. 22.
    Chatterjee, A., M.D. Chakravartiand I.N. Tayal: Fate of Rauwolscine - an Alkaloid of R. canescens - in the Body (Concentration of Rauwolscine in Blood). Proc. Indian sci. Congr. (33rd) Part III, 187 (1946).Google Scholar
  26. 23.
    Chatterjee, A. und P. Karrer: Untersuchung über Corynanthein. II. Hely. chim Acta 33, 802 (1950).CrossRefGoogle Scholar
  27. 24.
    Chatterjee, A. and S. Gosh Mazumdar: Alkaloid from Glycosmis pentaphylla CORREA. Science and Culture (India) 17, 306 (1952).Google Scholar
  28. 25.
    Chatterjee, A. and S. Pakrashi: Yobyrine, the Selenium Dehydrogenation Product of Rauwolscine. Proc. Indian Sci. Congr. (4oth) Part III, p. 355 (1953).Google Scholar
  29. 25 a.
    Chatterjee, A. and S. Pakrashi: Yobyrine, the Selenium Dehydrogenation Product of Rauwolscine. Science and Culture (India) 18, 443 (1953).Google Scholar
  30. 25 a.
    Chatterjee, A. and S. Pakrashi: Yobyrine, the Selenium Dehydrogenation Product of Rauwolscine. Science and Culture (India) 18, 443 (1953).Google Scholar
  31. 27.
    Chatterjee, A. and S. Pakrashi: Studies on the Infra-red Spectra of Rauwolscine and its Acetyl Derivative. VII. J. Indian chem. Soc. (1953) (1n press).Google Scholar
  32. 28.
    Chatterjee, A. and S. Pakrashi: Selenium Di-oxide Oxidation of Yobyrine, the Selenium Dehydrogenation Product of Rauwolscine. VIII. J. Indian chem. Soc. (1953) (in press).Google Scholar
  33. 29.
    Chaudhuri, R.N., M.N. RAI Chaudhuriand N.K. Chakravorty: Rauwolfia serpentina in Essential Hypertension. Indian med. Gaz. 86, 348 (1951).Google Scholar
  34. 30.
    Chopra, R.N., B.C. Bose, J.C. Guptaand I.C. Chopra: Alkaloids of Rauwolfia serpentina: A Comparative Study of Their Pharmacological Action and Their Role in Experimental Hypertension. J. Indian med. Res. 30, 319 (1942).Google Scholar
  35. 31.
    Chopra, R.N. and M.D. Chakravarti: A Preliminary Note on the Pharmacological Action of the Alkaloids of Rauwolfia serpentine BENTH. J. Indian med. Res. 29, 763 (1941)Google Scholar
  36. 32.
    Chopra, R.N., N.N. Das and S.N. Mukherjee: The Action of Ajmaline on Nerve Impulses. J. Indian med. Res. 24, 1125 (1937).Google Scholar
  37. 33.
    Chopra, R.N., J.C. Gupta, B.C. Bose and I.C. Chopra: Hypnotic Effect of Rauwolfia serpentine: The Principle Underlying this Action, its Probable Nature. J. Indian med. Res. 31, 71 (1943).Google Scholar
  38. 33 a.
    Chopra, R.N., J.C. Gupta and B. Mukherjee: The Pharmacological Action of an Alkaloid Obtained from Rauwolfia serpentine BENTH. J. Indian med. Res. 21, 261 (1933).Google Scholar
  39. 34.
    Clemo, G.R. and G.A. Swan: The Constitution of Yohimbine. I. J. chem. Soc. ( London ) 1946, 617.Google Scholar
  40. 35.
    Deger, E.C.: Allgemeine Untersuchung einer von den Indianern gegen Schlangengift und Malaria verwandten Pflanze. Arch. Pharmaz. u. Ber. dtsch. pharmaz. Ges. 275, 496 (1937).CrossRefGoogle Scholar
  41. 36.
    Dewar, M.J.S. and F.E. King: Constitution of Yohimbine. Nature (London) 148, 25 (1941).CrossRefGoogle Scholar
  42. 37.
    Durand, T.H. and B.D. Jackson: Index Kewensis. Oxford: Clarendon Press. Suppl. 1, 358 (1886–1895).Google Scholar
  43. 38.
    Elderfield, R.C. and A.P. Gray: Alstonia Alkaloids. III. Further Investigation of Alstonine, Reduction, Ozonolysis, and Spectrographic Studies. The Structure of Alstonine. J. org. Chemistry 16, 506 (1951).CrossRefGoogle Scholar
  44. 39.
    Gellert, E. und B. Witkop: Die Identität des Alkaloids Kamassin mit Quebrachamin. Helv. chim. Acta 35, 114 (1952).Google Scholar
  45. 40.
    Goodson, J. A.: Echitamine in Alstonia Barks. J. chem. Soc. ( London ) 1932, 2626.Google Scholar
  46. 40 a.
    Goutarel, R., M.-M. Janot und V. Prelog: Über die Konstitution des Sempervirins. Experientia 4, 24 (1948).Google Scholar
  47. 41.
    Greshoff, M.: Mittheilungen aus dem chemisch-pharmakologischen Laboratorium des Botanischen Gartens zu Buitenzorg (Java). Ber. dtsch. chem. Ges. 23, 3537 (1890).Google Scholar
  48. 42.
    Gupta, J.C., S. Ghosh, A.T. Duttaand B.S. Kahali: A Note on the Hypnotic Principle of Rauwolfia serpentine. J. Amer. pharmac. Assoc., Sci. Ed. 36, 416 (1947) •Google Scholar
  49. 43.
    Gupta, J.C., B.S. Kahaliand A. Dutt: The Hypnotic Effect of a Resin Fraction Isolated from the Root of Rauwolfia serpentine BENTH. Obtained from Dehra Dun. J. Indian med. Res. 32, 183 (1944).Google Scholar
  50. 44.
    Hahn, G. und A. Hansel: Synthese von 5: 6: 3: 14-Tetrahydro-yobyrinen. Ber. dtsch. chem. Ges. 71, 2192 (1938).Google Scholar
  51. 45.
    Hahn, G. und H. Werner: Synthese von Tetrahydro-harman (4-Carbolin)Systemen unter physiologischen Bedingungen. III. Synthese des YohimbinGerüstes. Liebigs Ann. Chem. 520, 123 (1935).Google Scholar
  52. 46.
    Harmsma, A.: Determination of the Absorption Power of Ergot Alkaloids in the Ultraviolet and its Practical Application. Pharmac. Weekbl. 65, 1114 (1928).Google Scholar
  53. 47.
    Harvey, D.G., E.J. Miller and W. Ronson: The Adamkiewicz, Hopkins and Cole, and Rosenheim Tests for Tryptophan An Investigation of the Configuration of the Organic Molecule Responsible for the Colour Formation and its Bearing on the Constitution of Yohimbine, with a Note on the Action of Formaldehyde on Tryptophan. J. chem. Soc. ( London ) 1941, 153.Google Scholar
  54. 48.
    Haworth, R.D.: A New Alkaloid from Holarrhena antidysenterica Seeds. J. chem. Soc. ( London ) 1932, 631.Google Scholar
  55. 49.
    Henry, T.A.: The Plant Alkaloids. 4th ed. Philadelphia and Toronto Blakiston Co. 1949Google Scholar
  56. 50.
    Hesse, O.: Über die Alkaloide der Ditarine. Liebigs Ann. Chem. 203, 144 (1880).Google Scholar
  57. 51.
    Hesse, O.: Beitrag zur Kenntnis der australischen Alstoniarinde. Liebigs Ann. Chem. 205, 360 (1880).Google Scholar
  58. 52.
    Hill, A.W.: Index Kewensis. Oxford: Clarendon Press. Suppl. VI, 172 (1916–1920).Google Scholar
  59. 53.
    Hill, A.W.: Index Kewensis. Suppl. VII, 205 (1921–1925).Google Scholar
  60. 54.
    Hill, A.W.: Index Kewensis. Suppl. VIII, 202 (1926–193o).Google Scholar
  61. 55.
    Hill, A.W.: Index Kewensis. Suppl. IX, 232 (1931–1935).Google Scholar
  62. 55 a.
    Hill, A.W. and E.J. Salisbury: Index Kewensis. Suppl. X, 191 (1936–1940).Google Scholar
  63. 56.
    Hooker, J.D. and B.D. Jacxson: Index Kewensis. 2, 692 (1895).Google Scholar
  64. 57.
    Irani (Miss), R.J.: Chemistry of Kurchi Seeds. IV. Isolation of Galactose From the Picric Acid Hydrolysis of the Glycoalkaloid. Current Sci. (India) 15, 229 (1946).Google Scholar
  65. 58.
    Itallie, L. Van and A.J. Steenhauer: Rauwolfia serpentina BENTH. Arch. Pharmaz. u. Ber. dtsch. pharmaz. Ges. 270, 313 (1932).CrossRefGoogle Scholar
  66. 59.
    Jacobs, W.A. and E.L. Gustus: Strophanthin. XVII. Dehydration and Lactone Cleavage in Isostrophanthic Acid Derivatives. J. biol. Chemistry 84, 183 (1929).Google Scholar
  67. 60.
    Jacobs, W.A. and E.L. Gustus: Strophanthin. XI. The. Hydroxyl Groups of Strophanthidin. J. biol. Chemistry 74, 795 (1927).Google Scholar
  68. 61.
    Jacoas, W.A. and A. Hoffmann: Strophanthin IX. On Crystalline Kombe Strophanthin. J. biol. Chemistry 67, 609 (1926).Google Scholar
  69. 69 a.
    Janot, M.-M., R. Goutarel et J. Massonneau: Structure de la mayumbine. C. R. hebd. Séances Acad. Sci. 234, 850 (1952).Google Scholar
  70. 62.
    Janot, M.-M., R. Goutarel und V. Prelog: Über die Konstitution des Corynantheins. Heiv. chim Acta 34, 2207 (1951).Google Scholar
  71. 62 a.
    Jobst, J. und O. Hesse: Über die Ditarinde. Liebigs Ann. Chem. 178, 49 (1875).Google Scholar
  72. 62 b.
    Julian, P.L., W.J. Karpel, A. Magnaniand E.W. Meyer: Studies in the Indole Series. X. Yohimbine, Part 2. The Synthesis of Yobyrine, Yobyrone and “Tetrahydroyobyrine”. J. Amer. chem. Soc. 70, 180 (1948).CrossRefGoogle Scholar
  73. 63.
    Karrer, P. und P. Enslin: Die Konstitution des „Alstyrins“. Hely. chim. Acta 33, 100 (1950).Google Scholar
  74. 63 a.
    Karrer, P. und P. Enslin: Untersuchungen übèr Corynanthein. Rely. chim. Acta 32, 1390 (1949).Google Scholar
  75. 64.
    Karrer, P., R. Schwyzerund A. Flam: Die Konstitution des Corynantheins und Dihydro-corynantheins. Heiv. chim. Acta 35, 851 (1952).Google Scholar
  76. 65.
    Karrer, P., R. Schwyzer, A. Flamund R. Saemann: Dehydrierung von Yohimbylalkohol mit Selen und Palladium-Kohle. Heir. chim. Acta 35, 865 (1952).Google Scholar
  77. 66.
    Karschulin, M.: Spectrographic Investigation of Yohimbine. Arch. Hemiju i. Farm. (Yougosl.) 5, 227 (1931).Google Scholar
  78. 67.
    Kharasch, M.S., D.W. Stanger, M.A. Bloodgoodand R. R. Legault: Spectroscopic Similarity Between Ergot (Lysergic Acid) and the Yohimbine Alkaloids. Science (New York) 83, 36 (1936).CrossRefGoogle Scholar
  79. 68.
    Kirtikar, R.K. and B.D. Basu: Indian Medicinal Plants. II. Bahadurganj, Allahabad (India). 1918, p. 777 (in English).Google Scholar
  80. 69.
    Koepfli, J.B.: Chemical Investigation of Rauwolfia caftra. I. Rauwolfine. J. Amer. chem. Soc. 54, 2412 (1932).CrossRefGoogle Scholar
  81. 70.
    Leonard, N.J. and R.C. Elderfield: Alstonia Alkaloids. I. Degradation of Alstonine to ß-Carboline Bases and the Reduction of Tetrahydroalstonine with Sodium and Butyl Alcohol. J. org. Chemistry 7, 556 (1942).Google Scholar
  82. 70 a.
    Levy, P.R. and R. Robinson: Calycanthidine. Festschrift KARRER, S. 39 (1949)Google Scholar
  83. 71.
    Mendlik, F. und J.P. Wibaut: Die Dehydrierung des Yohimbins. (Vorl. Mitt.). Recueil Tray. chim Pays-Bas 48, 191 (1929).CrossRefGoogle Scholar
  84. 72.
    Mendlik, F. und J.P. Wibaut: Über Yohimbin (2. Mitt.). Recueil Tray. chim. Pays-Bas 50, 91 (1931).CrossRefGoogle Scholar
  85. 72 a.
    Merrill, D.E.: The Upper Burma Plants Collected by Captain F Kingdon Ward on the Vernay-Cutting Expedition, 1938–1939. Brittonia 4, 20 (1941).CrossRefGoogle Scholar
  86. 72 b.
    Müller, JM, E. Schlittler und H.J. Bein: Reserpin, der sedative Wirkstoff aus Rauwolfia serpentina BENTH. Experientia 8, 338 (1952).CrossRefGoogle Scholar
  87. 73.
    Mukerji, B., B.K. Ghosh and L.B. Siddons: Search for Antimalarial Drug in the Indigenous Materia Medica. I. Alstonia scholaris F. BR. Indian med. Gaz. 77, 723 (1942).Google Scholar
  88. 74.
    Mukherji, D., R. Robinson and E. Schlittler: Chemistry of Ajmaline. Rauwolfine of van Itallie and Steenhauer. Experientia 5, 215 (1949).CrossRefGoogle Scholar
  89. 75.
    Mukherjee, J.: Studies on the Pharmacology of Rauwolscine, the Alkaloid of Rauwolfia canescens LINN. Science and Culture (India) 18, 6 (1952).Google Scholar
  90. 76.
    Mukherjee, J.: Studies on the Action of Rauwolscine Hydrochloride, the Alkaloid of Rauwolfia canescens LINN., on the Amphibian and Heart Muscles. Indian J. Physiol. and allied Sci. 6, 4 (1953)Google Scholar
  91. 77.
    Prain, D.: Index Kewensis. Oxford: Clarendon Press. Suppl. III, 149 (i9or1905).Google Scholar
  92. 78.
    Prain, D.: Index Kewensis. Suppl. IV. 198 (1906–1910).Google Scholar
  93. 78 a.
    Prain, D.: Index Kewensis Suppl. V, 214 (1911–1915).Google Scholar
  94. 79.
    Prelog, V.: Über das Sempervirin. Hely. chim. Acta 31, 588 (1948).Google Scholar
  95. 80.
    Raymond-Hamet: Ajmalinine, the Alkaloid from Ophioxylum serpentanum WILLD. of Selective Paralyzing Action on Vasoconstrictors Reactive to Adrenaline. Bull. Sci. pharmacol. 43, 364 (1936).Google Scholar
  96. 81.
    Raymond-Hamet: Sur un nouveau faux Iboga pharmacologiquement actif. C. R. hébd. Séances Acad. Sci. 210, 789 (194o).Google Scholar
  97. 82.
    Raymond-Hamet: Sur quelques propriétés pharmacologiques d’une drogue alexitère et antimalarique du Guatemala: le chalchupa. C. R. Séances Soc. biol. 129, 462 (1938).Google Scholar
  98. 82 a.
    Rindl, M. and P.W.G. Groenewoud: The Chemistry of Rauwolfianatalensis. Trans. Roy. Soc. South Africa 21, 55 (1932).CrossRefGoogle Scholar
  99. 82 b.
    Robinson, R. and H. Suginome: Experiments on the Synthesis of Physostigmine (Eserine). Part II. Synthesis of a Base which is Believed to be dl-• Noreserethole. J. Chem. Soc. ( London ) 1932, 304.Google Scholar
  100. 83.
    Rossi, L., A. Del Boca and R. Lobo: Analytical Studies of Yohimbine. IV. A New Colour Reaction for the Recognition of Yohimbine. Anal. farm. bioquim. (Buenos Aires) 3, 51 (1932).Google Scholar
  101. 84.
    Schlemmer, F. und, H. Schmitt: Spektrographische Untersuchungen über Mutterkorn. I. Die wirksamen Inhaltsstoffe des Mutterkorns. Arch. Pharmaz. u. Ber. dtsch. pharmaz. Ges. 270, 15 (1932).Google Scholar
  102. 85.
    Schlittler, E. und H. Schwarz: Über das Alkaloid Serpentin aus Rauwolfia serpentina Benth. Helv. chim. Acta 33, 1463 (1950).Google Scholar
  103. 86.
    Schlittler, E., H. Schwarzund F. Bader: IsolieIung VOn AlstOnin aus afrikanischen Rauwolfia-Arten. Helv. chim. Acta 35, 271 (1952).Google Scholar
  104. 87.
    Schömer, A.: Estimation of Yohimbine in Corynanthe yohimbi. Pharm. Zentralh. 63, 385 (1922).Google Scholar
  105. 88.
    Schwarz, H. und E. Schlittler: Über die Konstitution natürlicher und synthetischer quaternärer ß-Carboline, ihre Absorptionsspektren und die Konstitutionsermittlung ihrer Hydrierungsprodukte. Helv. chim Acta 34, 629 (1951).CrossRefGoogle Scholar
  106. 89.
    Sharp, T.M.: The Alkaloids of Alstonia Barks. I. A. constricta F. MUELL. J. chem. Soc. ( London ) 1934, 287.Google Scholar
  107. 90.
    Sharp, T.M.: The Alkaloids of Alstonia Barks. III. Alstonine. J. chem. Soc. ( London ) 1938, 1353.Google Scholar
  108. 91.
    Siddiqui, S.: A Note on the Alkaloids of Rauwolfia serpentine BENTH. J. Indian chem. Soc. 16, 421 (1939).Google Scholar
  109. 92.
    Siddiqui, S. and P.P. Pillay: The Alkaloids of Holarrhena antidysenterica. I. Three New Alkaloids from the Bark of Indian Holarrhena and New Methods of Isolation and Further Purification of Conessine. J. Indian chem. Soc. 9, 553 (1932).Google Scholar
  110. 93.
    Siddiqui, S. and R.H. Siddiqui: The Alkaloids of Holarrhena antidysenterica. III. Studies in the Action of BrCN on Conessine and its N-Demethylation to iso-Conessimine and Conimine. J. Indian chem. Soc. 11, 787 (1934)Google Scholar
  111. 94.
    Siddiqui, S. and R.H. Siddiqui: Chemical Examination of the Roots of Rauwolfia serpentine BENTH. J. Indian chem. Soc. 8, 667 (1931).Google Scholar
  112. 95.
    Siddiqui, S. and R.H. Siddiqui: The Alkaloids of Rauwolfia serpentins BENTH. I. J. Indian chem. Soc. 9, 539 (1932)Google Scholar
  113. 96.
    Siddiqui, S. and R.H. Siddiqui: The Alkaloids of Rauwolfia serpentins BENTH. II. Studies in the Ajmaline Series. J. Indian chem. Soc. 12, 37 (1935)Google Scholar
  114. 97.
    Stoll, A., J. Renz und W. Kreis: k-Strophanthosid, das Hauptglucosid der Samen von Strophanthus hombé. Hely. chim. Acta 20, 1484 (1937).Google Scholar
  115. 98.
    Thiselton-Dyer, W.T.: Index Kewensis. Oxford: Clarendon Press. Suppl. III, 156 (1901–1905).Google Scholar
  116. 99.
    Webb, L.J.: Guide to the Medicinal and Poisonous Plants of Queensland. Council for sci. and ind. Res., Australia, Bull. No. 232, 19 (1948).Google Scholar
  117. 100.
    Wehmer, C.: Die Pflanzenstoffe. II. Jena: G. Fischer. 1931, p. 99o.Google Scholar
  118. 100.
    Wehmer, C.: Die Pflanzenstoffe. II. Jena: G. Fischer. 1931, p. 99o.Google Scholar
  119. 101.
    Wibaut, J.P. und A.J.P. Van Gastel: Über Yohimbin (3. Mitt.). Recueil Tray. chim. Pays-Bas 54, 85 (1935).CrossRefGoogle Scholar
  120. 102.
    Witkop, B.: Zur Konstitution des Yohimbins und seiner Abbauprodukte. Liebigs Ann. Chem. 654, 83 (1943).Google Scholar
  121. 103.
    Witkop, B.: On the Stereochemistry of Yohimbine. J. Amer. chem. Soc. 71, 2559 (1949).CrossRefGoogle Scholar
  122. 104.
    Wokes, F. and H. Crocker: Biological and Spectroscopic Tests on Ergot Alkaloids with Notes on the Maurice Smith Colour Test. Quart. J. Pharmac. Pharmacol. 4, 420 (1931).Google Scholar
  123. 105.
    Woodward, R.B.: Biogenesis of Strychnos Alkaloids. Nature (London) 162, 155 (1948)CrossRefGoogle Scholar
  124. 106.
    Woooward, R.B. and W.M. Mclamore: The Synthesis of Sempervirine Methochloride. J. Amer. chem. Soc. 71, 379 (1949)Google Scholar
  125. 107.
    Woodward, R.B. and B. Witkop: The Structure of Sempervirine. J. Amer. chem. Soc. 71, 379 (1949)Google Scholar

Copyright information

© Springer-Verlag Wien 1953

Authors and Affiliations

  • Asima Chatterjee
    • 1
  1. 1.CalcuttaIndia

Personalised recommendations