The Macula pp 123-131 | Cite as

Cataract extraction in age-related macular degeneration: the ECAM-Study — an ongoing trial

  • Simon Brunner
  • C. I. Falkner
  • I. Krebs
  • A. Abri
  • S. Binder


At the end of the Millennium 6.5% of the population were older than 75 years [26], that means 500.000 people for Austria and 5.3 million for Germany, respectively.


Cataract Surgery Contrast Sensitivity Cataract Extraction Senile Cataract Extracapsular Cataract Extraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References (ECAM-1)

  1. 1.
    Klein R, Klein BEK, Jensen SC, Mares-Perlman JA, Cruickshanks KJ, Palta M (1999) Age-related maculopathy in a multiracial United States population. Ophthalmology 106: 1056–65PubMedCrossRefGoogle Scholar
  2. 2.
    Sperduto RD, Seigel D (1980) Senile lens and senile macular changes in a population-based sample. Am J Ophthalmol 90: 86–91PubMedGoogle Scholar
  3. 3.
    Klein R, Wang Q, Klein BEK, Moss SE, Meuer SM (1995) The relationship of age-related maculopathy, cataract and glaucoma to visual acuity. Invest Ophthalmol Vis Sci 36: 18–91Google Scholar
  4. 4.
    De la Paz MA (1998) Age-related macular degeneration: update and controversies. Advanced vitreous surgery course in: Duke University Eye CenterGoogle Scholar
  5. 5.
    Young RW (1988) Solar radiation and age-related macular degeneration. Sury Ophthalmol 32: 252–69CrossRefGoogle Scholar
  6. 6.
    Gjessing HGA (1953) Gibt es einen Antagonismus zwischen Cataracta senilis and Haabscher seniler Makulaveränderungen? Acta Ophthalmol 31: 401–21Google Scholar
  7. 7.
    Liu IY, White L, LaCroix AZ (1989) The association of age-related macular degeneration and lens opacities in the aged. Am J Public Health 79: 765–9PubMedCrossRefGoogle Scholar
  8. 8.
    Klein R, Klein BEK, Wang Q, Moss SE (1994) Is age-related maculopathy associated with cataracts? Arch Ophthalmol 112: 191–6PubMedCrossRefGoogle Scholar
  9. 9.
    Stolba U, Binder S, Velikay M (1989) Does cataract surgery with lens implantation influence the course of age-related macular degeneration? J Fr Ophthalmol 12: 897–901Google Scholar
  10. 10.
    Pollack A, Markovich A, Bukelman A, Oliver M (1996) Age-related macular degeneration after extracapsular cataract extraction with intraocular lens implantation. Ophthalmology 103: 1546–54PubMedGoogle Scholar
  11. 11.
    Van der Schaft TL, Mooy CM, de Bruijn WC, Mulder PGH, Pameyer JH, de Jong PTVM (1994) Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens. Br J Ophthalmol 78: 441–5PubMedCrossRefGoogle Scholar
  12. 12.
    Klein R, Klein BEK, Jensen SC, Cruickshanks KJ (1998) The relationship of ocular factors to the incidence and progression of age-related maculopathy. Arch Ophthalmol 116: 506–13PubMedGoogle Scholar
  13. 13.
    Vingerling JR, Klaver CCW, Hofman A, de Jong PTVM (1997) Cataract extraction and age-related macular degeneration: the Rotterdam study. Invest Ophthalmol Vis Sci 38 (4): 472Google Scholar
  14. 14.
    Shuttleworth GN, Luhishi EA, Harrad RA (1998) Do patients with age related maculopathy and cataract benefit from cataract surgery? Br J Ophthalmol 82: 611–16PubMedCrossRefGoogle Scholar
  15. 15.
    Chylack LT, Leske MC, Sperduto R, Khu P, McCarthy D (1988) Lens opacities classification system. Arch Ophthalmol 106: 330–4PubMedCrossRefGoogle Scholar
  16. 16.
    Vanden Bosch MA, Wall M (1997) Visual acuity scored by the letter-by-letter or probit methods has lower retest variability than the line assignment method. Eye 11: 411–17CrossRefGoogle Scholar
  17. 17.
    Halliday BL, Ross JE (1983) Comparison of 2 interferometers for predicting visual acuity in patients with cataract. Br J Ophthalmol 67: 273–7PubMedCrossRefGoogle Scholar
  18. 18.
    Klein RK, Davis MD, Magli YL, Segal P, Klein BEK, Hubbard L (1991) The Wisconsin age-related maculopathy grading system. Ophthalmology 98: 1128–34PubMedGoogle Scholar
  19. 19.
    Shin DS, Javornik NB, Berger JW (1999) Computer-assisted, interactive fundus image processing for macular drusen quantitation. Ophthalmology 106: 1119–25PubMedCrossRefGoogle Scholar
  20. 20.
    Kirkpatrick JNP, Spencer T, Manivannan A, Sharp A (1995) Quantitative image analysis of macular drusen from fundus photographs and scanning laser ophthalmoscope images. Eye 9: 48–55PubMedCrossRefGoogle Scholar
  21. 21.
    Blair CJ, Ferguson J (1979) Exacerbation of senile macular degeneration following Cataract extraction. AJO 87: 77–83Google Scholar
  22. 22.
    Barrett BT, Davison PA, Eustace P (1995) Clinical comparison of three techniques for evaluating visual function behind cataract. Eye 9: 722–7PubMedCrossRefGoogle Scholar
  23. 23.
    Munier A, Gunning T, Kenny D, O’Keefe M (1998) Causes of blindness in the adult population of the Republic of Ireland. Br J Ophthalmol 82 (6): 630–3PubMedCrossRefGoogle Scholar
  24. 24.
    Ho T, Law MN, Goh LG, Yoong T (1997) Eye diseases in the elderly in Singapore. Singapore Med J 38 (4): 149–55PubMedGoogle Scholar
  25. 25.
    Reidy A, Minassian DC, Vafidis G, Joseph J, Farrow S, Wu J, Desai P (1998) Prevalence of serious eye disease and visual impairment in a north London population: population-based, cross-sectional study. BMJ 316 (7145): 1643–6PubMedCrossRefGoogle Scholar
  26. 26.
    Armbrecht AM, Findlay C, Kaushal S, Aspinall P, Hill AR (2000) Is cataract surgery justified in patients with age related macular degeneration? A visual function and quality of life assessment. Br J Ophthalmol 84 (12): 1343–8PubMedCrossRefGoogle Scholar
  27. 27.
    Steinberg EP, Tielsch JM, Schein OD, Javitt JC, Sharkey P, Cassard SD (1994) The VF-14 — An Index of functional impairment in patients with cataract. Arch Ophthalmol 112: 630–8PubMedCrossRefGoogle Scholar
  28. 28.
    Linder M, Chang TS, Scott IU, Hay D, Chambers K, Sibley LM, Weis E (1999) Validity of the Visual Function Index (VF-14) in patients with retinal disease. Arch Ophthalmol 117: 1611–16PubMedGoogle Scholar
  29. 29.
    Early Treatment Diabetic Retinopathy Study (1985) Manual of Operations, Chapter 12Google Scholar
  30. 30.
    Radner W, Willinger U, Obermayer W, Mudrich C, Velikay-Parel M, Eisenwort B (1998) A new reading chart for simultaneous determination of reading vision and reading speed. Klin Monatsbl Augenheilkd 213 (3): 174–81PubMedCrossRefGoogle Scholar
  31. 31.
    Vingerling JR, Dielemans I, Hofman A, Grobbee DE, Hijmering M (1995) The prevalence of age-related maculopathy in the Rotterdam study. Ophthalmology 102 (2): 205–10PubMedGoogle Scholar
  32. 32.
    Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis M, Jong PT, Klaver CC, Klein BE, Klein R, et al (1995) An international classification System for age-related maculopathy and age-related macular degeneration. The international ARM Epidemiological Study Group. Sury Ophthalmol 39 (5): 367–74CrossRefGoogle Scholar
  33. 33.
    Chylack LT, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL (1993) The Lens Opacities Classification System Ill. Arch Ophthalmol 111: 831–6PubMedCrossRefGoogle Scholar
  34. 34.
    Dickinson At, Sparrow JM, Duke AM, Thompson JR, Gibson JM (1997) Prevalence of age-related maculopathy at two points in time in an elderly British population. Eye 11 (Pt 3): 301–14PubMedCrossRefGoogle Scholar
  35. 35.
    Klaver CC, Vingerling JR (1997) Epidemiologie. In: Holz FG, Pauleikhoff D (Hrsg) Altersabhängige Makuladegeneration. Berlin, Heidelberg: SpringerGoogle Scholar
  36. 36.
    Barraquer J, Troutman RC, Rutllan (1965) Die Chirurgie des vorderen Augenabschnittes, vol I. Stuttgart: Ferd. Enke VerlagGoogle Scholar
  37. 37.
    Wilkinson CP (1982) The natural course of CME occurring in pseudophakic eyes. 24th International Congress of Ophthalmology. San FranciscoGoogle Scholar
  38. 38.
    Falcone PM (1996) Vitreomacular traction syndrome confused with pseudophakic cystoid macular edema. Ophthalmic Surg Lasers 27 (5): 392–4PubMedGoogle Scholar
  39. 39.
    Vinores SA, Amin A, Derevjanik NL (1994) Immunhistochemical localisation of blood-retinal barrier and breakdown sites associated with post-surgical macular edema. Histochem J 26 (8): 655–65PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag/Wien 2004

Authors and Affiliations

  • Simon Brunner
    • 1
  • C. I. Falkner
    • 1
  • I. Krebs
    • 1
  • A. Abri
    • 1
  • S. Binder
    • 1
  1. 1.The Rudolph Foundation Hospital in Vienna, Department of OphthalmologyThe Ludwig-Boltzmann-Institute for Retinology and Biomicroscopic Laser SurgeryViennaAustria

Personalised recommendations