Skip to main content
SpringerLink
Log in

Der Nachweis menschenpathogener Virusarten mittels der Gewebekultur

  • Chapter
Handbuch der Virusforschung

Zusammenfassung

Durch die Untersuchungen von Carrel (34) mit dem Rousschen Hühnersarkom und die von Maitland und Maitland (184) mit dem Vaccinevirus wurde die Gewebekulturtechnik in die Virologie eingeführt. Schwierigkeiten der Technik wie auch die Fragestellungen, mit denen diese und auch spätere Untersuchungen durchgeführt wurden, verhinderten jedoch zunächst eine allgemeine Anwendung. Durch die überwiegende Verwendung der modifizierten Maitland-Technik war es nicht möglich, die Methode der Gewebekultur als solche selbsttragend zu gestalten. Der Nachweis der Virusvermehrung in der Gewebekultur mußte fast immer mittels des Tierversuches geführt werden. Die Fragestellung beschränkte sich, abgesehen von morphologischen Untersuchungen, die zum Studium der Viruszellbeziehungen durchgeführt wurden, weitgehend darauf, festzustellen, welche Gewebearten einer bestimmten Tierspecies einer gegebenen Virusart Vermehrungsmöglichkeiten bieten, die äußeren Kulturbedingungen festzulegen und die Veränderungen, die eine Virusart durch serienweise Gewebekulturpassagen erfährt, zu erfassen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Ackermann, W., A. Rabson and H. Kurtz: Growth characteristics of poliomyelitis virus in HeLa cell cultures: lack of parallelism in cellular injury and virus increase. Jour. Exp. Med. 100, 437 (1954).

    CAS  Google Scholar 

  2. Anderson, S. G.: Rubella virus in tissue culture. Lancet. 267, 1107 (1954).

    PubMed  CAS  Google Scholar 

  3. Andrewes, C. H., D. M. Chaproniere, A. E. H. Gompels, H. G. Pereira and A. T. Roden: Propagation of common cold virus in tissue cultures. Lancet, Sept. 12, p. 546 (1953).

    Google Scholar 

  4. Andrewes, C. H.: Virus III in tissue cultures. II. Further observations on the formation of inclusion bodies. III. Experiments bearing on immunity. Brit. J. Exp. Path. 10, 273 (1929).

    Google Scholar 

  5. Andrewes, C. H., F. B. Bang and F. M. Burnet: A short description of the myxovirus group. (Influenza and related viruses.) Virology 1, 176 (1955).

    PubMed  CAS  Google Scholar 

  6. Balducci, D., E. Zaiman and D. A. J. Tyrrell: Laboratory studies of APC and influenza C viruses. Brit. J. Exp. Path. 37, 205 (1956).

    PubMed  CAS  Google Scholar 

  7. Bang, F. B. and G. O. Gey: Comparative susceptibility of cultured cell strains to the virus of eastern equine encephalomyelitis. Bull. Johns Hopkins Hospital 91, 427 (1952).

    CAS  Google Scholar 

  8. — Pathology of the cell infected with virus. Morphological and biochemical aspects. Fed. Proc. 14, 619 (1955).

    PubMed  CAS  Google Scholar 

  9. Barer, R. and S. Joseph: Refractometry of living cells. Part III. Technical and optical methods. (Optical problems and interpretation.) Quart. J. Microsc. Sc. 96, 423 (1955).

    CAS  Google Scholar 

  10. Barer, R.: Phase contrast and interference microscopy in cytology. In “Physical techniques in biological research. Vol. III., Cells and tissues”. New York, Academic Press (1956).

    Google Scholar 

  11. Barski, G., J. Maurin et P. Lépine: Lésions nucléaires dans la culture du tissu nerveux et d’autre tissues embryonaires de poulet infectés avec le virus de l’herpès. Ann. Inst. Pasteur 76, 221 (1949).

    Google Scholar 

  12. Barski, G., et J. Maurin: Inclusions négriformes en culture de tissu nerveux en l’absence du virus rabique. Ann. Inst. Pasteur 78, 411 (1950).

    CAS  Google Scholar 

  13. Barski, G., P. Lépine, V. Monaci et G. de Brion: Culture in vitro du virus de la poliomyélite en présence de tissu tonsillaire humain. Ann. Inst. Pasteur 84, 825 (1953).

    CAS  Google Scholar 

  14. Barski, G., M. Endo et V. Monaci: Etude préliminaire des lésions cellulaires de la poliomyélite en culture in vitro sur une souche de fibroblastes humains. Ann. Inst. Pasteur 85, 264 (1953).

    CAS  Google Scholar 

  15. Barski, G., P. de Souza, V. Monaci, M. Endo et P. Lépine: Résultats de la culture in vitro du virus poliomyélitique sur différentes souches cellulaires d’origine humaine. Ann. Inst. Pasteur 85, 576 (1953).

    CAS  Google Scholar 

  16. Barski, G., R. Robineaux and M. Endo: Phase contrast cinematography of cellular lesion produced by poliomyelitis virus in vitro. Proc. Soc. Exp. Biol. Med. 88, 57 (1955).

    PubMed  CAS  Google Scholar 

  17. Baumeister, J. and C. A. Miller: The preparation of poliomyelitis complementfixing antigens from infected tissue culture fluids. J. Infect. Dis. 98, 27 (1956).

    PubMed  CAS  Google Scholar 

  18. Beale, A. J. and H. C. Hair: Rapid diagnosis of the herpetic variety of Kaposi’s varicelliform eruption by tissue culture methods. Canad. Med. Ass. Jour. 74, 443 (1956).

    CAS  Google Scholar 

  19. Beale, A. J., P. F. Stevens, N. Davis, W. Stackiw and A. J. Rhodes: The development of inclusions in tissue cultures of monkey kidney epithelial cells infected with poliomyelitis virus. Canad. J. Microbiol. 2, 298 (1956).

    CAS  Google Scholar 

  20. Bedson, S. P. and J. O. W. Bland: Morphological study of psittacosis virus, with description of a developmental cycle. Brit. J. Exp. Path. 13, 461 (1932).

    Google Scholar 

  21. Bell, J. A., W. P. Rowe, J. I. Engler, R. H. Parrott and R. J. Huebner: Pharyngo conjunctival fever. Epidemiological studies of a recently recognized disease entity. J. Am. Med. Ass. 157, 1083 (1955).

    CAS  Google Scholar 

  22. Benedek, A. L. and C. H. Kempe: Effect of vaccinia on cells grown in tissue culture. Proc. Soc. Exp. Biol. Med. 82, 520 (1953).

    PubMed  CAS  Google Scholar 

  23. Berge, T. O., B. England, C. Mauris, H. E. Shuey and E. H. Lennette: Etiology of acute respiratory disease among service personnel at Fort Ord, California, Am. J. Hyg. 62, 283 (1955).

    PubMed  CAS  Google Scholar 

  24. Berman, L. and C. S. Stulberg: Eight culture strains (Detroit) of human epithelial-like cells. Proc. Soc. Exp. Biol. Med. 92, 730 (1956).

    PubMed  CAS  Google Scholar 

  25. Black, F. L.: Poliomyelitis complement-fixing antibodies and their demonstration. Ann. New York Acad. Sci. 61(Art. 4), 781 (1955).

    CAS  Google Scholar 

  26. Black, F. L. and J. L. Melnick: Micro-epidemiology of poliomyelitis and herpes-B infections. Spread of the viruses within tissue cultures. J. Immunol. 74, 236 (1955).

    PubMed  CAS  Google Scholar 

  27. Black, F. L. and J. L. Melnick: The specificity of the complement fixation test in poliomyelitis. Yale J. Biol. Med. 26, 385 (1954).

    PubMed  CAS  Google Scholar 

  28. Black, F. L., M. Reissig and J. L. Melnick: Propagation of measles virus in a strain of human epidermoid cancer cells (Hep-2). Proc. Soc. Exp. Biol. Med. 93, 107 (1956).

    PubMed  CAS  Google Scholar 

  29. Bland, J. O. W. and R. G. Canti: The growth and development of psittacosis virus in tissue culture. Jour. Path. Bact. 40, 231 (1935).

    Google Scholar 

  30. Bland, J. O. W. and C. F. Robinow: The inclusion bodies of vaccinia and their relationship of the elementary bodies studied in cultures of rabbits cornea. Jour. Path. Bact. 48, 381 (1939).

    Google Scholar 

  31. Bodian, D.: Simplified method of dispersion of monkey cells with trypsin. Virology 4, 575 (1956).

    Google Scholar 

  32. Borysko, E. and P. Sapranaus: A new technique for comparative phasecontrast and electron microscope studies of cells grown in tissue culture, with an evaluation of the technique by means of time-lapse cinemicrographs. Bull. Johns Hopkins Hospital 95, 68 (1954).

    CAS  Google Scholar 

  33. Brown, G. C.: Virus excretion and antibody response in clinical and subclinical cases of poliomyelitis. Ann. New York Acad. Sci. 61(Art. 4), 989 (1955).

    CAS  Google Scholar 

  34. Bryant, J. C., W. R. Earle and E. V. Peppers: The effect of ultracentrifugation and hyaluronidase on the filtrability of chick-embryo extract for tissue culture. J. Nat. Cancer Inst. 14, 189 (1953).

    PubMed  CAS  Google Scholar 

  35. Bucciante, L.: zit. bei Levi, G.

    Google Scholar 

  36. Buchsbaum, R. and J. A. Kuntz: The effects of certain stimulants and depressants on individual fibroblasts in a perfusion chamber. Ann. New York Acad. Sci. 58(Art. 7), 1303 (1954).

    CAS  Google Scholar 

  37. Buckley, S. M., E. Whitney and F. Rapp: Identification by fluorescent antibody of developmental forms of psittacosis virus in tissue culture. Proc. Soc. Exp. Biol. Med. 90, 226 (1955).

    PubMed  CAS  Google Scholar 

  38. Buckley, S. M.: Visualization of poliomyelitis virus by fluorescent antibody. Arch. Virusforschg. 6, 388 (1956).

    CAS  Google Scholar 

  39. Burnet, F. M.: Principles of animal virology. New York, Academic Press (1955).

    Google Scholar 

  40. Burr, M. M., M. E. Campbell, J. F. Morgan and F. P. Nagler: Studies on the propagation of influenza and mumps viruses in tissue culture with chemically defined media. Canad. J. Microbiol. 1, 158 (1954).

    CAS  Google Scholar 

  41. Cameron, G.: Tissue culture technique. New York, Academic Press (1950).

    Google Scholar 

  42. Carrel, A.: Some conditions of the reproduction in vitro of the Rous virus. Jour. Exp. Med. 43, 647 (1926).

    CAS  Google Scholar 

  43. Casals-Ariet, J. and L. T. Webster: Characteristics of a strain of lymphocytic choriomeningitis virus encountered as a contaminant in tissue cultures of rabies virus. Jour. Exp. Med. 71, 147 (1940).

    CAS  Google Scholar 

  44. Chambers, V., W. M. Smith and C. A. Evans: Growth of neurotropic viruses in extraneural tissues. II. MM virus in various tissues of hamsters and mice. J. Immunol. 65, 605 (1950).

    PubMed  CAS  Google Scholar 

  45. — Neurotropic viruses in extraneural tissues. III. MM virus in human and murine testicular tissues. Proc. Soc. Exp. Biol. Med. 76, 213 (1951).

    PubMed  CAS  Google Scholar 

  46. Chanock, R. M.: Cytopathogenic effect of newcastle virus in monkey kidney cultures and interference with poliomyelitis viruses. Proc. Soc. Exp. Biol. Med. 89, 379 (1955).

    PubMed  CAS  Google Scholar 

  47. — Association of a new type of cytopathogenic myxovirus with infantile croup. J. Exp. Med. 104, 555 (1956).

    PubMed  CAS  Google Scholar 

  48. Cohen, A. and C. Waymouth: A new histological procedure for whole tissue cultures grown. in plasma. Science 108, 480 (1948).

    PubMed  CAS  Google Scholar 

  49. Cohen, S. M., I. Gordon, F. Rapp, J. C. Macaulay and S. M. Buckley: Fluorescent antibody and complement-fixation tests of agents isolated in tissue culture from measles patients. Proc. Soc. Exp. Biol. Med. 90, 118 (1955).

    PubMed  CAS  Google Scholar 

  50. Committee on the ECHO viruses. Enteric cytopathogenic human orphan (ECHO) viruses. Science 122, 1187 (1955).

    Google Scholar 

  51. Coons, A. H. and M. H. Kaplan: Localization of antigen in tissue cells. II. Improvements in a method for the detection of antigen by means of fluorescent antibody. Jour. Exp. Med. 91, 1 (1950).

    CAS  Google Scholar 

  52. Cooper, P. D.: A method for producing plaques in agar suspensions of animal cells. Virology 1, 397 (1955).

    PubMed  CAS  Google Scholar 

  53. Crowell, R. L. and J. T. Syverton: The viral range in vitro of a malignant human epithelial cell (strain HeLa, Grey). IV. The cytopathogenicity of C viruses. J. Immunol. 74, 169 (1955).

    PubMed  CAS  Google Scholar 

  54. Cruickshank, C. N. D. and E. J. L. Lowburg: Effect of antibiotics on tissue cultures of human skin. Brit. Med. J. No: 4793, 1070 (1952).

    Google Scholar 

  55. Cushing, R. T. and H. R. Morgan: Effects of some metabolic analogs on growth of mumps and influenza viruses in tissue cultures. Proc. Soc. Exp. Biol. Med. 79, 497 (1952).

    PubMed  CAS  Google Scholar 

  56. Daniels, J. B., M. D. Eaton and M. E. Perry: Effect of glucose on the growth of influenza virus in deembryonated eggs and tissue cultures. J. Immunol. 69, 321 (1952).

    PubMed  CAS  Google Scholar 

  57. Davis, D. C. and J. L. Melnick: Association of ECHO virus type 6 with aseptic meningitis. Proc. Soc. Exp. Biol. Med. 92, 839 (1956).

    PubMed  CAS  Google Scholar 

  58. Dekking, F. and K. McCarthy: Propagation of measles virus in human carcinoma cells. Proc. Soc. Exp. Biol. Med. 93, 1 (1956).

    PubMed  CAS  Google Scholar 

  59. Demuth, F.: zit. nach G. Levi.

    Google Scholar 

  60. Division of Laboratories and Research, New York State Health Department. Annual Report 1955, Albany (1955).

    Google Scholar 

  61. Doane, F., A. J. Rhodes and H. L. ’Ormsby: Tissue culture techniques in the study of herpertic infections of the eye. Am. J. Ophth. 40, 189 (1955).

    PubMed  CAS  Google Scholar 

  62. Dubes, G. R.: Differences among strains of poliomyelitis viruses in plaque size on monkey kidney cells. Virology 2, 284 (1956).

    PubMed  CAS  Google Scholar 

  63. Dulbecco, R.: Production of plaques in monolayer tissue cultures by single particles of an animal virus. Proc. Nat. Acad. Sci. (Wash.) 38, 747 (1952).

    CAS  Google Scholar 

  64. Dulbecco, R. and M. Vogt: Some problems of animal virology as studied by the plaque technique. Cold Spring Harbor Symp. 18, 273 (1953).

    CAS  Google Scholar 

  65. — Plaque formation and isolation of pure lines with poliomyelitis viruses. Jour. Exp. Med. 99, 167 (1954).

    CAS  Google Scholar 

  66. — One-step growth of western equine encephalomyelitis virus on chicken embryo cells grown in vitro and analysis of virus yields from single cells. Jour. Exp. Med. 99, 183 (1954).

    CAS  Google Scholar 

  67. — Biological properties of poliomyelitis viruses as studied by the plaque technique. Ann. New York Acad. Sci. 61(Art. 4), 790 (1955).

    CAS  Google Scholar 

  68. Duncan, D., A.E. Franklin, W. Wood and A. J. Rhodes: Cultivation of poliomyelitis virus in tissue culture. V. Observations on virus propagation in certain animal tissues with a synthetic nutrient medium. Canad. J. Med. Sci. 31, 75 (1953).

    CAS  Google Scholar 

  69. Duncan, D., N. Silverthorne, G. A. McNaughton, C. C. R. Johnson and A. J. Rhodes: Tissue culture methods in the laboratory diagnosis of cases of poliomyelitis with observations on the behaviour of Coxsackie viruses in tissue culture. Canad. J. Publ. Health 45, 55 (1954).

    CAS  Google Scholar 

  70. Duncan, D., A. J. Rhodes, G. A. McNaughton, C. C. R. Johnson and W. Wood: Aseptic meningitis: Isolation of Coxsackie and unidentified cytopathogenic viruses from cerebro spinal fluid by tissue culture methods. Canad. J. Publ. Health 46, 1 (1955).

    CAS  Google Scholar 

  71. Dunnebacke, T. H.: Correlation of the stage of cytopathic change with the release of poliomyelitis virus. Virology 2, 399 (1956).

    PubMed  CAS  Google Scholar 

  72. Eagle, H.: Propagation in a fluid medium of a human epidermoid carcinoma, strain K. B. Proc. Soc. Exp. Biol. Med. 89, 362 (1955).

    PubMed  CAS  Google Scholar 

  73. — The specific amino acid requirements of a human carcinoma cell (strain HeLa) in tissue culture. Jour. Exp. Med. 102, 37 (1955).

    CAS  Google Scholar 

  74. — The specific amino acid requirements of a mammalian cell (strain L) in tissue culture. J. Physiol. Chem. 214, 839 (1955).

    CAS  Google Scholar 

  75. Eagle, H., K. Habel, W. P. Rowe and R. J. Huebner: Viral susceptibility of a human carcinoma cell (strain KB). Proc. Soc. Exp. Biol. Med. 91, 361 (1956).

    PubMed  CAS  Google Scholar 

  76. Eagle, H. and K. Habel: The nutritional requirements for the propagation of poliomyelitis virus by the HeLa cell. J. Exp. Med. 104, 271 (1956).

    PubMed  CAS  Google Scholar 

  77. Earle, W. R.: Production of malignancy in vitro. IV. The mouse fibroblast cultures and changes seen in the living cells. J. Nat. Cancer Inst. 4, 165 (1943).

    CAS  Google Scholar 

  78. Earle, W. R., V. J. Evans, M. F. Edward and E. Duchesne: Influence of perforation design on growth of tissue cells under perforated cellophane sheets in vitro. J. Nat. Cancer Inst. 10, 291 (1949).

    PubMed  CAS  Google Scholar 

  79. Earle, W. R., J. C. Bryant and E. L. Schilling: Certain factors limiting the size of the tissue culture and the development of massive cultures. Ann. New York Acad. Sci. 58(Art. 7), 1000 (1954).

    CAS  Google Scholar 

  80. Eaton, M. B., M. E. Perry, C. G. Levenson and I. M. Cocke: Studies on the mode of action of aromatic diamidines on influenza and mumps virus in tissue culture. J. Immunol. 68, 321 (1952).

    PubMed  CAS  Google Scholar 

  81. Enders, J. F. and A. L. Florman: Persistence of vaccinia virus and chick-embryonic cells in suspended cell tissue cultures. Proc. Soc. Exp. Biol. Med. 49, 153 (1942).

    Google Scholar 

  82. Enders, J. F., T. H. Weller and F. C. Robbins: Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues. Science 109, 85 (1949).

    PubMed  CAS  Google Scholar 

  83. Enders, J. F.: The multiplication and properties of poliomyelitis viruses in cultures on human tissue. Second Internat. Poliomyelitis Conference, Kopenhagen 1951.

    Google Scholar 

  84. Enders, J. F.: General preface to studies on the cultivation of poliomyelitis viruses in tissue culture. J. Immunol. 69, 639 (1952).

    PubMed  CAS  Google Scholar 

  85. — Bovine amniotic fluid as tissue culture medium in cultivation of poliomyelitis and other viruses. Proc. Soc. Exp. Biol. Med. 82, 100 (1953).

    PubMed  CAS  Google Scholar 

  86. — Cytopathology of virus infections. (Particular reference to tissue culture studies.) Ann. Review Microbiol. 8, 473 (1954).

    CAS  Google Scholar 

  87. — Tissue cultures in the study of immunity. Retrospection and anticipation. J. Immunol. 73, 62 (1954).

    PubMed  CAS  Google Scholar 

  88. Enders, J. F. and T. C. Peebles: Propagation in tissue culture of cytopathogenic agents from patients with measles. Proc. Soc. Exp. Biol. Med. 86 277 (1954).

    PubMed  CAS  Google Scholar 

  89. Enders, J. F., J. A. Bell, J. H. Dingle, T. Francis jr., M. R. Hilleman, R. J. Huebner and A. M. Payne: “Adenoviruses”: Group name proposal for respiratory tract viruses. Science 124, 119 (1956).

    PubMed  CAS  Google Scholar 

  90. Evaluation of 1954 field trial of poliomyelitis vaccine. Summary report. Vaccine Evaluation Center. University of Michigan, Ann Arbor (April 12, 1955).

    Google Scholar 

  91. Evans, V. J. and W. R. Earle: The use of perforated cellophane for the growth of cells in tissue culture. J. Nat. Cancer Inst. 8, 103 (1947).

    PubMed  CAS  Google Scholar 

  92. Evans, V. J., J. C. Bryant, M. C. Fioramonti, W. T. McQuilkin, K. K. Sanford and W. R. Earle: Studies of nutrient media for tissue cells in vitro. I. A protein-free chemically defined medium for cultivation of strain L cells. Cancer Research 16, 77 (1956).

    PubMed  CAS  Google Scholar 

  93. Evans, V. J., J. C. Bryant, W. T. McQuilkin, M. C. Fioramonti, K. K. Sanford, B. B. Westfall and W. R. Earle: Studies of nutrient media for tissue cells in vitro. II. An improved protein-free chemically defined medium for long-term cultivation of strain L-929 cells. Cancer Research 16, 87 (1956).

    PubMed  CAS  Google Scholar 

  94. Evans, C. A., P. H. Byatt, V. C. Chambers and W. M. Smith: Growth of neurotropic viruses in extraneural tissues. VI. Absence of in vitro multiplication of poliomyelitis virus, Type I and II, after intratesticular inoculation of monkeys and other laboratory animals. J. Immunol. 72, 348 (1954).

    PubMed  CAS  Google Scholar 

  95. Farrell, L. N., W. Wood, A. E. Franklin, E. T. Shimada, H. G. Maomorine and A. J. Rhodes: Cultivation of poliomyelitis virus in tissue culture. VI. Methods for quantity production of poliomyelitis viruses in cultures of monkey kidney. Canad. J. Publ. Health 44, 273 (1953).

    CAS  Google Scholar 

  96. Fastier, L. B.: Infectivity titrations of the viruses of Western equine encephalomyelitis and Newcastle disease by tissue culture methods. J. Immunol. 72, 341 (1954).

    PubMed  CAS  Google Scholar 

  97. Feller, A. E., J. F. Enders and T. H. Weller: The prolonged coexistence of vaccinia virus in high titre and living cells in roller tube cultures of chick embryonic tissues. Jour. Exp. Med. 72, 367 (1940).

    CAS  Google Scholar 

  98. Feller, A. E.: Technique and application of roller tube cultures. In Hdb. Virusforsch. 3. Bd. (II. Ergänzungsband) Wien, Springer (1950).

    Google Scholar 

  99. Fischer, A.: The application of soybean inhibitor in tissue culture. Science (Lancaster, Pa.) 109, 611 (1949).

    CAS  Google Scholar 

  100. Fjelde, A.: Human tumor cells in tissue culture. Cancer 8, 845 (1955).

    PubMed  CAS  Google Scholar 

  101. Fogh, J.: Adsorption, latent period and early virus release in monkey kidney and HeLa cell cultures infected with poliomyelitis. Fed. Proc. 14, 212 (1955).

    Google Scholar 

  102. — Latent period in monkey kidney and HeLa cell monolayer cultures infected with poliomyelitis virus. Proc. Soc. Exp. Biol. Med. 89, 494 (1955).

    PubMed  CAS  Google Scholar 

  103. — Relation between multiplicity of exposure, adsorption, and cytopathogenic effect of poliomyelitis virus in monkey kidney tissue cultures. Virology 1, 324 (1955).

    PubMed  CAS  Google Scholar 

  104. Fogh, J. and R. O. Lund: Plaque formation of poliomyelitis viruses on human amnion cell cultures. Proc. Soc. Exp. Biol. Med. 90, 80 (1955).

    PubMed  CAS  Google Scholar 

  105. Fogh, J.: Relation between multiplicity of exposure, adsorption, and cytopathogenic effect of poliomyelitis virus in monkey kidney tissue cultures. Virology 1, 324 (1955).

    PubMed  CAS  Google Scholar 

  106. Fowle, A. M. C., A. Cockeram and H. L. Ormsby: Virus isolations from patients with keratoconjunctivitis. Am. J. Ophth. 40, 180 (Pt. II) (1955).

    PubMed  CAS  Google Scholar 

  107. Pox, J. P.: The cultivation of yellow fever virus. I. Factors influencing the multiplication of 17 D virus in tissue culture. Am. J. Hyg. 46, 1 (1947).

    Google Scholar 

  108. Franklin, A. E., D. Duncan, W. Wood and A. J. Rhodes: Cultivation of Lansing poliomyelitis virus in tissue culture. II. Utilization of glucose in synthetic medium. Proc. Soc. Exp. Biol. Med. 79, 715 (1952).

    PubMed  CAS  Google Scholar 

  109. — Cultivation of poliomyelitis virus in tissue culture. IV. Further observation on virus propagation in human tissues with a synthetic nutrient medium. Canad. J. Med. Sci. 31, 64 (1953).

    CAS  Google Scholar 

  110. Friend, C.: Effect of 2, 6-diaminopurine on virus of Russian spring summer encephalitis in tissue culture. Proc. Soc. Exp. Biol. Med. 78, 150 (1951).

    PubMed  CAS  Google Scholar 

  111. Frisch, A. W. and V. Jentoft: Use of trypsin in preparing subcultures of monkey testicular tissue. Proc. Soc. Exp. Biol. Med. 82, 322 (1953).

    PubMed  CAS  Google Scholar 

  112. — Preservation of monkey testicular tissue with human albumin. Proc. Soc. Exp. Biol. Med. 82, 624 (1953).

    PubMed  CAS  Google Scholar 

  113. Frisch, A. W., V. Jentoft, R. Barger and E. J. Losli: A human epithelium-like cell (Maben) derived from an adenocarcinoma of lung: Isolation, continuous propagation, and effects of selected viruses. Am. J. Clin. Path. 25, 1107 (1955).

    PubMed  CAS  Google Scholar 

  114. Fulton, F. and P. Armitage: Surviving tissue suspensions for influenza virus titration. J. Hyg. 49, 247 (1951).

    PubMed  CAS  Google Scholar 

  115. Gajdusek, D. C.: Suspended cell tissue cultures for study of virus growth kinetics. Proc. Soc. Exp. Biol. Med. 83, 621 (1953).

    PubMed  CAS  Google Scholar 

  116. Gajdusek, D. C., R. O. Anslow, E. J. Hubbell and R. H. Yager: Tissue culture studies of Venezuelan equine encephalomyelitis virus. I. Propagation in human uterine tissue. J. Immunol. 72, 224 (1954).

    PubMed  CAS  Google Scholar 

  117. Gey, G. O.: An improved technique for massive tissue culture. Am. J. Cancer 17, 752 (1933).

    Google Scholar 

  118. Gey, G. O. and M. K. Gey: The maintenance of human normal cells and tumor cells in continous culture. I. Preliminary report: Cultivation of mesoblastic tumors and normal tissue and notes on methods of cultivation. Am. J. Cancer 27, 45 (1936).

    Google Scholar 

  119. Gey, G. O. and F. B. Bang: Experimental studies on cultural behaviour and the infectivity of lymphopathia venerea virus maintained in tissue culture. Bull. Johns Hopkins Hospital, 65, 393 (1939).

    Google Scholar 

  120. — Viruses and cells — a study in tissue culture applications. Trans. New York Acad. Sci. Ser. II, 14, 15 (1951).

    CAS  Google Scholar 

  121. Gey, G. O., W. D. Coffman and M. T. Kubicek: Tissue culture studies of proliferative capacity of cervical carcinoma and normal epithelium. Cancer Res. 12, 264 (1952).

    Google Scholar 

  122. Gey, G. O., F. B. Bang and M. K. Gey: Responses of a variety of normal and malignant cells to continous cultivation, and some practical applications of these responses to problems in the biology of disease. Ann. New York Acad. Sci. 58(Art. 7), 976 (1954).

    CAS  Google Scholar 

  123. — An evaluation of some comparative studies on cultured strains of normal and malignant cells of animals and man. Texas Rep. Biol. Med. 12, 805 (1954).

    CAS  Google Scholar 

  124. Ginsberg, H. S., E. Gold and W. S. Jordan: Tryptose phosphate broth as supplementary factor for maintenance of HeLa cell tissue cultures. Proc. Soc. Exp. Biol. Med. 89, 66 (1955).

    PubMed  CAS  Google Scholar 

  125. Ginsberg, H. S., E. Gold, W. S. Jordan, S. Katz, G. F. Badger and J. H. Dingle: Relation of the new respiratory agents to acute respiratory diseases. Am. J. Publ. Health 45, 915 (1955).

    CAS  Google Scholar 

  126. Ginsberg, H. S.: Characteristics of the new respiratory viruses (Adeno-viruses). I. Qualitative and quantitative aspects of the neutralization reaction. J. Immunol. 77, 271 (1956).

    PubMed  CAS  Google Scholar 

  127. Ginsberg H. S.: Characteristics of the new respiratory viruses (Adeno-viruses). II. Stability to temperature and pH alteration. Proc. Soc. Exp. Biol. Med. 93, 48 (1956).

    PubMed  CAS  Google Scholar 

  128. Granoff, A.: Plaque formation with influenza strains. Virology 1, 252 (1955).

    PubMed  CAS  Google Scholar 

  129. Grayston, J. T., P. B. Johnston, M. E. Smith and C. Loosli: An improved technique for the neutralization test with adenoviruses in HeLa cell cultures. J. Infect. Dis. 99, 188 (1956).

    PubMed  CAS  Google Scholar 

  130. Haagen, E. und B. Crodel: Untersuchungen über das japanische Enzephalitisvirus. Zbl. Bakt. I. (Orig.) 142, 269 (1938).

    Google Scholar 

  131. Haan, J. de: Die Methode der Durchströmung in der Gewebekultur. Resultate und Aussichten. Arch. exper. Zellforsch. 11, 365 (1931).

    Google Scholar 

  132. Haas, R und H. Wulff: Die Züchtung des Influenzavirus in Gewebekulturen von Frettchennieren. Giorn. Microbiol. 1, 65 (1955).

    Google Scholar 

  133. Habel, K., N. C. Gregg and W. D. McBride: Susceptibility to poliomyelitis virus of HeLa cells adapted to growth in horse serum medium. Proc. Soc. Exp. Biol. Med. 90, 87 (1955).

    PubMed  CAS  Google Scholar 

  134. Haff, R. F. and H. E. Swim: Serial propagation of 3 strains of rabbit fibroblasts; their susceptibility to infection with vaccinia virus. Proc. Soc. Exp. Biol. Med. 93, 200 (1956).

    PubMed  CAS  Google Scholar 

  135. Hallauer, C.: Die Züchtung der Virusarten außerhalb ihrer Wirte. A. Die Viruszüchtung im Gewebeexplantat. Hdb. Virusforschung. Bd. I/1 pg. 369, 1938, Wien, Julius Springer.

    Google Scholar 

  136. — Über das Verhalten von Hühnerpestvirus in der Gewebekultur. Z. Hyg. 113 61 (1931).

    Google Scholar 

  137. — Noch nicht veröffentlicht.

    Google Scholar 

  138. Hanks, J. H. and R. E. Wallace: Relation of oxygen and temperature in the preservation of tissue by refrigeration. Proc. Soc. Exp. Biol. Med. 71, 196 (1949).

    PubMed  CAS  Google Scholar 

  139. Harding, C. V., D. Harding, W. F. McLimans and G. Rake: Cytological changes accompanying the growth of poliomyelitis virus in cells of human origin (strain HeLa). Virology 2, 109 (1956).

    PubMed  CAS  Google Scholar 

  140. Hare, J. D. and H. R. Morgan: Studies on the factors essential to the initiation and maintenance of multiplication of psittacosis virus (6 BC strain) in deficient cells in tissue culture. Jour. Exp. Med. 99, 461 (1954).

    CAS  Google Scholar 

  141. Hazen, E. L. and R. Brown: Fungicidin, an antibiotic produced by a soil actinomycete. Proc. Soc. Exp. Biol. Med. 76, 93 (1951).

    PubMed  CAS  Google Scholar 

  142. Healy, G. M., D. C. Fisher and R. C. Parker: Nutrition of animal cells in tissue culture. X. Synthetic medium No. 858. Proc. Soc. Exp. Biol. Med. 89, 71 (1955).

    PubMed  CAS  Google Scholar 

  143. Henle, G., F. Deinhardt and A. Girardi: Cytolytic effects of mumps virus in tissue cultures of epithelial cells. Proc. Soc. Exp. Biol. Med. 87, 386 (1954).

    PubMed  CAS  Google Scholar 

  144. Henle, G., A. Girardi and W. Henle: A non-transmissible cytopathogenic effect of influenza virus in tissue culture accompanied by formation of non infectious hemagglutinins. Jour. Exp. Med. 101, 25 (1955).

    CAS  Google Scholar 

  145. Henle, W., S. Harris, G. Henle, T. N. Harris, M. E. Drake, F. Mangold and J. Stokes: Studies on the agent of infectious hepatitis. I. Propagation of the agent in tissue culture and in the embryonated hen’s egg. Jour. Exp. Med. 92, 271 (1950).

    CAS  Google Scholar 

  146. Hetherington, D. C. and J. S. Craig: Tissue culture growth stimulants from ground frozen-dried chick embryos. Proc. Soc. Exp. Biol. Med. 44, 282 (1940).

    Google Scholar 

  147. Hetherington, D. C.: Frozen-dried serum as a medium constituent for tissue cultures. Proc. Soc. Exp. Biol. Med. 57, 196 (1944).

    CAS  Google Scholar 

  148. — The preservation of media for the culture of bacteria and tissues. In “Biological Applications of Freezing and Drying”, ed R. J. C. Harris, 1954, New York, Academic Press.

    Google Scholar 

  149. Hilleman, M. R. and J. H. Werner: Recovery of new agent from patients with acute respiratory illness. Proc. Soc. Exp. Biol. Med. 85, 183 (1954).

    PubMed  CAS  Google Scholar 

  150. Hilleman, M. R., J. H. Werner, H. E. Dascomb and R. L. Butler: Epidemiologic investigations with respiratory disease virus RI-67. Am. J. Publ. Health 45, 203 (1955).

    CAS  Google Scholar 

  151. Hogue, M. J., R. McAllister, A. E. Greene and L. L. Corriell: The effect of poliomyelitis virus on human brain cells in tissue culture. Jour. Exp. Med. 102, 29 (1955).

    CAS  Google Scholar 

  152. Horstmann, D. and R. W. McCollum: Poliomyelitis virus in human blood during the “minor illness” and the asymptomatic infection. Proc. Soc. Exp. Biol. Med. 82, 434 (1953).

    PubMed  CAS  Google Scholar 

  153. Hotta, S. and G. A. Evans: Cultivation of mouse-adapted dengue virus (type 1) in rhesus monkey tissue culture. J. Infect. Dis. 98, 88 (1956).

    PubMed  CAS  Google Scholar 

  154. — Cultivation of type 2 dengue virus in rhesus kidney tissue culture. Proc. Soc. Exp. Biol. Med. 93, 153 (1956).

    PubMed  Google Scholar 

  155. Hsiung, G. D. and J. L. Melnick: Plaque formation with poliomyelitis, coxsackie and orphan (ECHO) viruses in bottle cultures of monkey epithelial cells. Virology 1, 533 (1955).

    PubMed  CAS  Google Scholar 

  156. Huang, C. H.: Titration and neutralization of the western strain of equine encephalomyelitis virus in tissue culture. Proc. Soc. Exp. Biol. Med. 51, 396 (1942).

    Google Scholar 

  157. — Titration of St. Louis encephalitis virus and Jungeblut-Sanders mouse virus in tissue culture. Proc. Soc. Exp. Biol. Med. 54, 158 (1943).

    CAS  Google Scholar 

  158. — A visible method for titration and neutralization of viruses on the basis of pH changes in tissue cultures. Proc. Soc. Exp. Biol. Med. 54, 160 (1943).

    CAS  Google Scholar 

  159. — Further studies on the titration and neutralization of the western strain of equine encephalomyelitis virus in tissue culture. Jour. Exp. Med. 78, 111 (1943).

    CAS  Google Scholar 

  160. Huebner, R. J., W. P. Rowe, T. G. Ward, R. H. Parrott and J. A. Bell: Adenoidal-pharyngeal-conjunctival agents. A newly recognized group of common viruses of the respiratory system. New Engl. J. Med. 251, 1077 (1954).

    PubMed  CAS  Google Scholar 

  161. Hughes, A. F. W.: The Techniquê of ciné-photo-micrography of living cells. J. Roy. Micr. Soc. 69, 53 (1949).

    PubMed  CAS  Google Scholar 

  162. Hull, R. N. and J. M. Lavelle: Further studies on the inhibition of the cytopathogenic effect of poliomyelitis viruses by antibiotic M-8450 in tissue culture. Ann. New York Acad. Sci. 58(Art. 7), 1188 (1954).

    CAS  Google Scholar 

  163. Hull, R. N., J. R. Minner and J. W. Smith: New viral agents recovered from tissue cultures of monkey kidney cells. I. Origin and properties of cytopathogenic agents S.V. 1, S.V. 2, S.V. 4, S.V. 6, S.V. 11, S.V. 12 and S.V. 15. Am. J. Hyg. 63, 204 (1956).

    PubMed  CAS  Google Scholar 

  164. Hummeler, K., D. Kirk and M. Ostapiak: Aseptic meningitis caused by Cox-sackie virus with isolation of virus from cerebro spinal fluid. J. Am. Med. Ass. 156, 676 (1954).

    CAS  Google Scholar 

  165. Hsu, T. C.: Cytological studies on HeLa strain of human cervical carcinoma. I. Observations on mitosis and chromosomes. Texas Rep. Biol. Med. 12, 833 (1954).

    CAS  Google Scholar 

  166. Jacoby, F.: The toxicity of sulphadiazine and sulphaguanidine to macrophages in vitro. Brit. J. Exp. Path. 26, 137 (1945).

    CAS  Google Scholar 

  167. Jawetz, E., S. Kimura, A, N. Nicholas, P. Thygeson and L. Hanna: New type of APC virus from epidemic Keratoconjunctivitis. Science 122, 1190 (1955).

    PubMed  CAS  Google Scholar 

  168. Jawetz, E., S. J. Kimura, L. Hanna, V. R. Coleman, P. Thygeson and A. Nicholas: Studies on the etiology of epidemic keratoconjunctivitis. Am. J. Ophth. 40, 200 (Pt. II) (1955).

    PubMed  CAS  Google Scholar 

  169. Jordan, W. S.: Human nasal cells in continuous culture. I. Establishment of two lines of epithelial-like cells. Proc. Soc. Exp. Biol. Med. 92, 867 (1956).

    PubMed  Google Scholar 

  170. — Human nasal cells in continuous culture. II. Virus susceptibilities. Proc. Soc. Exp. Biol. Med. 92, 872 (1956).

    PubMed  Google Scholar 

  171. Kanazawa, K.: Sur la culture in vitro du virus de la rage. Jap. Jour. Exp. Med. 15, 17 (1937).

    Google Scholar 

  172. Kawakita, Y.: Cultivation in vitro of the virus of Japanese encephalitis. Jap. Jour. Exp. Med. 17, 211 (1939).

    Google Scholar 

  173. Kawakita, Y. and T. Tazaki: The action of immune serum on the Japanese encephalitis virus cultivated in vitro. Jap. Med. Jour. 1, 17 (1948).

    CAS  Google Scholar 

  174. Kibrick, S.: Comparative susceptibility of roller tube cultures of different tissues to poliomyelitis viruses. Ann. New York Acad. Sci. 61(Art. 4), 822 (1955).

    CAS  Google Scholar 

  175. Kilham, L. and H. W. Murphy: Propagation of mumps virus in suckling mice and in mouse embryo tissue cultures. Proc. Soc. Exp. Biol. Med. 80, 495 (1952).

    PubMed  CAS  Google Scholar 

  176. Kirby, W. M. M. and C. A. Evans: Tissue culture isolation of Coxsackie Group B viruses in aseptic meningitis. J. Am. Med. Ass. 159, 743 (1955).

    CAS  Google Scholar 

  177. Kjellén, L. and A. Svedmyr: Studies on herpes simplex virus in tissue culture. Arch. Virusforschung 4, 373, 379 (1954).

    Google Scholar 

  178. Kjellén, L.: Studies on an unidentified group of cytopathic agents. Arch. Virusforschung 6, 45 (1955).

    Google Scholar 

  179. Kligler, I. J. and H. Bernkopf: Studies on the cultivation and antigenic characters of rabies virus. Am. J. Hyg. Sec. B. 33, 1 (1941).

    Google Scholar 

  180. Klöne, W.: unveröffentlicht.

    Google Scholar 

  181. Klöne, W. und H. H. Heunert: Einwirkung des Poliomyelitisvirus auf Gewebekulturzellen. Inst. Wiss. Film, Göttingen (1955).

    Google Scholar 

  182. Klöne, W.: Untersuchungen zur Cytopathogenität des Poliomyelitisvirus (Typ Leon). Arch. Virusforschung 6, 36 (1955).

    Google Scholar 

  183. — Untersuchungen über den zeitlichen Ablauf der Infektion und den Ausbreitungsmechanismus des Poliomyelitisvirus in Gewebekulturen. Zbl. Bakt. I. Orig. 162, 431 (1955).

    Google Scholar 

  184. — Untersuchungen über den Einfluß der Poliomyelitisvirus-Infektion auf die Teilung von Gewebekulturzellen. Exp. Cell. Res. 9, 541 (1955).

    PubMed  Google Scholar 

  185. Koprowski, H. and E. H. Lennette: Effect of in vitro cultivation on the pathogenicity of West Nile virus. Jour. Exp. Med. 84, 181 (1946).

    Google Scholar 

  186. — Effect of in vitro cultivation on the pathogenicity of Venezuelan equine encephalomyelitis virus. Jour. Exp. Med. 84, 205 (1946).

    Google Scholar 

  187. Krech, U. and I. J. Lewis: Propagation of B-virus in tissue culture. Proc. Soc. Exp. Biol. Med. 87, 174 (1954).

    PubMed  CAS  Google Scholar 

  188. Krech, U.: The antigenic potency of non infectious poliomyelitis virus as determined by its liberating effect on active virus neutralized by immune serum. Jour. Exp. Med. 101, 331 (1955).

    CAS  Google Scholar 

  189. Kret, A.: Virological diagnosis of poliomyelitis by means of a simplified technique for the propagation of the virus in cultures of strain HeLa human epithelial cells. Arch. Virusforschung 6, 60 (1955).

    CAS  Google Scholar 

  190. Kunz, L. J.: An analysis of the relationships between the antibodies reacting with certain antigens of the mumps virus. Doctoral Thesis. Harvard University (1951).

    Google Scholar 

  191. Lahelle, O.: Development of human fibroblastic subculture, and isolation of poliomyelitis viruses in subcultures. Acta Path. et Microbiol. Scand. 36, 47 (1955).

    CAS  Google Scholar 

  192. Le Bouvier, G. L.: Interference and cell protection by poliomyelitis virus in tissue culture. Nature 174, 649 (1954).

    Google Scholar 

  193. — Observations on the poliomyelitis complement-fixation test. Brit. J. Exp. Path. 34, 300 (1953).

    Google Scholar 

  194. Lebrun, J.: Cellular localization of herpes simplex virus by means of fluorescent antibody. Virology 2, 496 (1956).

    PubMed  CAS  Google Scholar 

  195. Ledinko, N., J.T. Riordan and J. L. Melnick: Differences in cellular pathogenicity of two immunologically related poliomyelitis viruses as revealed in tissue culture. Proc. Soc. Exp. Biol. Med. 78, 83 (1951).

    PubMed  CAS  Google Scholar 

  196. Ledinko, N., J. T. Riordan and J. L. Melnick: Multiplication of poliomyelitis viruses in tissue cultures of monkey testes. I. Growth curves of type 1 (Brunhilde) and type 2 (Lansing) strains and description of a quantitative neutralization test. Am. J. Hyg. 55, 323 (1952).

    PubMed  CAS  Google Scholar 

  197. Ledinko, N. and J. L. Melnick: Poliomyelitis viruses in tissue culture. III. Susceptibility of testicular tissue from immune monkeys. Proc. Soc. Exp. Biol. Med. 81, 144 (1952).

    PubMed  CAS  Google Scholar 

  198. — Interference between poliomyelitis viruses in tissue culture. Jour. Exp. Med. 100, 247 (1954).

    CAS  Google Scholar 

  199. Ledinko, N.: Production of plaques with influenza virus. Nature 175, 999 (1955).

    PubMed  CAS  Google Scholar 

  200. Leighton, J.: A sponge matrix method for tissue culture. Formation of organized aggregates of cells in vitro. J. Nat. Cancer Inst. 12, 545 (1951).

    PubMed  CAS  Google Scholar 

  201. Leighton J.: Provisional catalogue of etablished cell strains. Am. Tissue Culture Assoc., New York (1956).

    Google Scholar 

  202. Lennette, E. H. and H. Koprowski: Interference between viruses in tissue culture. Jour. Exp. Med. 83, 195 (1946).

    Google Scholar 

  203. Levi, G.: Explantation, besonders die Struktur und die biologischen Eigenschaften der in vitro gezüchteten Zellen und Gewebe. Erg. Anat. Entwicklungsgesch. 31, 363 (1934).

    Google Scholar 

  204. Lewis, M. R. and W. H. Lewis: The cultivation of tissues from chick embryos in solutions of NaCl, CaCl2, KCl and NaHCO3. Anat. Rec. 5, 277 (1911).

    Google Scholar 

  205. Li, C. P. and M. Schaeffer: A simplified method for cultivation of poliomyelitis virus in tissue culture. Science 118, 107 (1953).

    PubMed  CAS  Google Scholar 

  206. Lipton, M. M. and A. J. Steigman: A simplified colorimetric test for poliomyelitis virus and antibody. Proc. Soc. Exp. Biol. Med. 88, 114 (1955).

    PubMed  CAS  Google Scholar 

  207. — Practicability of shipping HeLa cell suspensions for use in color test for poliomyelitis antibodies. Proc. Soc. Exp. Biol. Med. 90, 367 (1955).

    PubMed  CAS  Google Scholar 

  208. Luria, S. E: General Virology, New York, John Wiley & Sons, 1953.

    Google Scholar 

  209. Luria, S.: Méthodes statistiques appliquées a l’étude du mode d’action des ultra virus. Ann. Inst. Pasteur 64, 415 (1940).

    Google Scholar 

  210. Lwoff, A., R. Dulbecco, M. Vogt and M. Lwoff: Kinetics of the release of poliomyelitis virus from single cells. Virology 1, 128 (1955).

    PubMed  CAS  Google Scholar 

  211. Lycke, E.: Cultivation of the Coxsackie virus subgroup B in cultures of human embryonic tissues. Arch. Virusforsch. 6, 412 (1956).

    PubMed  CAS  Google Scholar 

  212. Lynn, J. W. and H. R. Morgan: Cytopathogenicity of animal viruses in vitro. Arch. Path. 57, 301 (1954).

    Google Scholar 

  213. MacCallum, F. O. and G. M. Findlay: The cultivation of lymphocytic choriomeningitis in tissue culture. Brit. J. Exp. Path. 21, 110 (1940).

    Google Scholar 

  214. Magill, T. P. and Th. Francis: Studies with human influenza virus cultivated in artificial medium. Jour. Exp. Med. 63, 803 (1936).

    CAS  Google Scholar 

  215. Maitland, H. B. and M. C. Maitland: Cultivation of vaccinia virus without tissue culture. Lancet 2, 596 (1928).

    Google Scholar 

  216. Malamos, B.: Züchtung des Lymphogranuloma inguinale Virus auf Kaninchen-Kornea-Epithel-Kulturen. Zbl. Bakt. I. Orig. 143, 1 (1938).

    Google Scholar 

  217. Mason, H. C. and J. Woodie: Inhibition of poliomyelitis virus by Japanese B encephalitis (JBE) virus in HeLa tissue culture. Fed. Proc. 14, 471 (1955).

    Google Scholar 

  218. Maximow, A.: Tissue cultures of young mammalian embryos. Carnegie Inst. Wash. Publ. Contrib. Embryol. 16, No. 80, 47 (1925).

    Google Scholar 

  219. McNair Scott, T. F., C. F. Burgoon, L. L. Corriell and H. Blank: The growth of the virus of herpes simplex in rabbit corneal cells grown in tissue culture with parallel observations on the development of the intranuclear inclusion body. J. Immunol. 71, 385 (1953).

    Google Scholar 

  220. Melnick, J. L. and J. T. Riordan: Poliomyelitis viruses in tissue culture. IV. Protein-free nutrient media in stationary and roller tube cultures. Proc. Soc. Exp. Biol. Med. 81, 208 (1952).

    PubMed  CAS  Google Scholar 

  221. Melnick, J. L. and K. Ågren: Poliomyelitis and Coxsackie viruses isolated from normal infants in Egypt. Proc. Soc. Exp. Biol. Med. 81, 621 (1952).

    PubMed  CAS  Google Scholar 

  222. Melnick, J. L., J. T. Riordan, E. C. Curnen and A. D. Macrae: Tissue culture pathogenic agents other than poliomyelitis virus isolated from cases of suspected poliomyelitis. Fed. Proc. 12, 454 (1953).

    Google Scholar 

  223. Melnick, J. L.: Applications of tissue culture methods to epidemiological studies of poliomyelitis. Am. J. Publ. Health 44, 571 (1954).

    CAS  Google Scholar 

  224. Melnick, J. L. and D. D. Banker: Isolation of B-virus (Herpes group) from the central nervous system of a rhesus monkey. Jour. Exp. Med. 100, 181 (1954).

    CAS  Google Scholar 

  225. Melnick, J. L.: Tissue culture techniques and their application to original isolation, growth, and assay of poliomyelitis and orphan viruses. Ann. New York, Acad. Sci. 61(Art. 4), 754 (1955).

    CAS  Google Scholar 

  226. Melnick, J. L., C. Rappaport, D. D. Banker and P. N. Bhatt: Stabilized suspensions of monkey kidney cells suitable for intercontinental shipment. Proc. Soc. Exp. Biol. Med. 88, 676 (1955).

    PubMed  CAS  Google Scholar 

  227. Melnick, J. L. and E. M. Opton: Assay of poliomyelitis neutralizing antibody in disposable plastic panels. Bull. Wld. Hlth. Org. 14, 129 (1956).

    CAS  Google Scholar 

  228. Melnick, J. L.: Tissue culture methods for the cultivation of poliomyelitis and other viruses. In “Diagnostic procedures for virus and rickettsial diseases”. New York, Am. Publ. Health Assoc. (1956).

    Google Scholar 

  229. Miller, C. A.: Growth of poliomyelitis viruses in large stationary cultures. Proc. Soc. Exp. Biol. Med. 82, 450 (1953).

    Google Scholar 

  230. Milzer, A., S. O. Levinson, K. Vanderboom and P. Adelman: Cultivation of poliomyelitis virus (Lansing strain) in human embryonic and placental tissues. Proc. Soc. Exp. Biol. Med. 74, 136 (1950).

    PubMed  CAS  Google Scholar 

  231. Mogabgab, W. J., I. J. Green and O. C. Dierkhising: Primary isolation and propagation of influenza virus in cultures of human embryonic renal tissue. Science 120, 320 (1954).

    PubMed  CAS  Google Scholar 

  232. — Characteristics of influenza A and B viruses isolated and propagated in cultures of human embryonic tissue. J. Lab. a. Clin. Med. 44, 899 (1954).

    Google Scholar 

  233. Mogabgab, W. J., G. L. Simpson, O. C. Dierkhising and I. J. Green: Growth and cytopathogenic effect of “unadapted” influenza A and B viruses in human and monkey cell cultures. Fed. Proc. 14, 472 (1955).

    Google Scholar 

  234. Molloy, E.: Cultivation of the St. Louis encephalitis virus. Proc. Soc. Exp. Biol. Med. 44, 563 (1940).

    Google Scholar 

  235. Monaci, V. e F. Bonetti: Ricerche sulla poliomelite. Nota IV. Isolamento e tipizzazione del virus poliomelitico medinate cultura su tessuto embrionale umano e su testicolo di scimmia. Bollettino I. S. M. 33, 313 (1954).

    CAS  Google Scholar 

  236. Moore, A. E., L. Sabachewsky and H. W. Toolan: Culture characteristics of four permanent lines of human cancer cells. Cancer Res. 15, 598 (1955).

    PubMed  CAS  Google Scholar 

  237. Morann, G. L. and J. L. Melnick: Poliomyelitis virus in tissue culture. VI. Use of kidney epithelium grown on glass. Proc. Soc. Exp. Biol. Med. 84, 558 (1953).

    PubMed  CAS  Google Scholar 

  238. Morgan, H. R. and R. W. Wiseman: Growth of psittacosis virus in roller tube tissue culture; use in a vaccine. J. Infect. Dis. 79, 131 (1946).

    PubMed  CAS  Google Scholar 

  239. Morgan, J. F. and R. C. Parker: Use of antitryptic agents in tissue culture. I. Crude soybean trypsin-inhibitor. Proc. Soc. Exp. Biol. Med. 71, 665 (1949).

    PubMed  CAS  Google Scholar 

  240. Morgan, J. F., H. J. Morton and R. C. Parker: Nutrition of animal cells in tissue culture. I. Initial studies on a synthetic medium. Proc. Soc. Exp. Biol. Med. 73, 1 (1950).

    PubMed  CAS  Google Scholar 

  241. Morgan, C., S. A. Ellison, H. M. Rose and D. H. Moore: Structure and development of viruses as observed in the electron microscope. I. Herpes simplex virus. Jour. Exp. Med. 100, 195 (1954).

    CAS  Google Scholar 

  242. Morgan, J. F., M. E. Campbell and H. J. Morton: The nutrition of animal tissues cultivated in vitro. I. A survey of natural materials as supplements to synthetic medium 199. J. Nat. Cancer Inst. 16, 557 (1955)

    PubMed  CAS  Google Scholar 

  243. Morton, H., J. F. Morgan and R. C. Parker: Nutrition of animal cells in tissue culture. V. Effect of initial treatment of cultures on their survival in a synthetic medium. J. Cell a. Comp. Physiol. 38, 389 (1951).

    CAS  Google Scholar 

  244. Nauck, E. G. und C. Robinow: Untersuchungen über Guarnierische Körperchen in der Gewebekultur. Zbl. Bakt. I. Orig. 135, 437 (1935).

    Google Scholar 

  245. Neva, F. A. and J. F. Enders: Cytopathogenic agents isolated from patients during an unusual epidemic exanthem. J. Immunol. 72, 307 (1954).

    PubMed  CAS  Google Scholar 

  246. — Isolation of a cytopathogenic agent from an infant with a disease in certain respects resembling roseola infantum. J. Immunol. 72, 315 (1954).

    PubMed  CAS  Google Scholar 

  247. Noyes, W. F.: A simple technic for demonstrating plaque formation with virus of vaccinia. Proc. Soc. Exp. Biol. Med. 83, 426 (1953).

    PubMed  CAS  Google Scholar 

  248. Noyes, W. F. and B. K. Watson: Studies on the increase of vaccine virus in cultured human cells by means of the fluorescent antibody technique. Jour. Exp. Med. 102, 237 (1955).

    CAS  Google Scholar 

  249. Noyes, W. F.: Visualization of Egypt 101 virus in the mouse’s brain and in cultured human carcinoma cells by means of fluorescent antibody. Jour. Exp. Med. 102, 243 (1955).

    CAS  Google Scholar 

  250. Oddo, F. G.: Osservazioni morfologiche su cellule HeLa infettate con virus poliomelitico. Rivista dell’Istituto siero terapico italiano 3, 197 (1956).

    Google Scholar 

  251. Owens, O. H., M. K. Gey and G. O. Gey: Growth of cells in agitated fluid medium. Ann. New York Acad Sci. 58(Art. 7), 1039 (1954).

    Google Scholar 

  252. Parker, F. and R. N. Nye: Studies on filtrable viruses. II. Cultivation of herpes virus. Am. J. Path. 1, 337 (1925).

    PubMed  CAS  Google Scholar 

  253. Parker, R. C. and A. J. Hollender: Propagation of rabies virus in tissue culture. Proc. Soc. Exp. Biol. Med. 60, 94 (1945).

    PubMed  CAS  Google Scholar 

  254. Parker, R. C., J. F. Morgan and H. J. Morton: Toxicity of rubber stoppers for tissue cultures. Proc. Soc. Exp. Biol. Med. 76, 444 (1951).

    PubMed  CAS  Google Scholar 

  255. Parrott, R. H., W. P. Rowe, R. J. Huebner, H. W. Bernton and N. B. McCullough: Outbreak of febrile pharyngitis and conjunctivitis associated with type 3 adenoidal-pharyngeal-conjunctival virus infection. New Engl. J. Med. 251, 1087 (1954).

    PubMed  CAS  Google Scholar 

  256. Pearson, H. E. and J. F. Enders: Cultivation of influenza A virus in roller tubes. Proc. Soc. Exp. Biol. Med. 48, 140 (1941).

    Google Scholar 

  257. Pereira, H. G. and A. E. H. Gompels: The growth of fowl-plague and new-castle-disease viruses in roller tube cultures. J. Path. a. Bact. 67, 109 (1954).

    CAS  Google Scholar 

  258. Perry, V. P., V.J. Evans and W. R. Earle: Cultivation of large cultures of HeLa cells in horse serum. Science 121, 805 (1955).

    PubMed  CAS  Google Scholar 

  259. Plotz, H.: Un moyen simple pour déceler la présence du virus de la peste aviaire dans les cultures, sans avoir recours a l’inoculation aux animaux. C. r. Soc. biol. 118, 1400 (1935).

    Google Scholar 

  260. Plotz, H. and R. Reagan: In vitro cultivation of the street virus of rabies. Science 95, 102 (1942).

    PubMed  CAS  Google Scholar 

  261. Poleff, L.: Die neuen Ergebnisse der experimentellen Trachomforschung. Zbl. ges. Ophthal. 61, 1 (1953).

    Google Scholar 

  262. — Etat actuel des principeaux problèmes de trachomatologie expérimentale. Rev. Int. du Trachome 4, 434 (1954).

    Google Scholar 

  263. Pollard, M. and R. H. Bussell: Oncolytic effect of viruses in tissue cultures. Proc. Soc. Exp. Biol. Med. 80, 574 (1952).

    PubMed  CAS  Google Scholar 

  264. Pollard, M., R. Bussell and C. S. Snyder: The effect of viruses on human neoplasms in tissue cultures. Texas Rep. Biol. Med. 12, 336 (1954).

    CAS  Google Scholar 

  265. Pollard, M.: Cellular immunity as demonstrated in tissue cultures with viruses. Texas Rep. Biol. Med. 13, 317 (1955).

    CAS  Google Scholar 

  266. Pomerat, C. M.: Methods in Medical research, Vol. IV (1951). Year Book Publishers.

    Google Scholar 

  267. Pomerat, C. M. and C. D. Leake: Short term cultures for drug assays: General considerations. Ann. New York Acad. Sci. 58(Art. 7), 1110 (1954).

    CAS  Google Scholar 

  268. Porter, K. R. and F. L. Kallman: Significance of cell participates as seen by electron microscopy. Ann. New York Acad. Sci. 54, 882 (1952).

    CAS  Google Scholar 

  269. Puck, Th. T., Ph. I. Marcus and St. J. Ciectura: Clonal growth of mammalian cells in vitro. Growth characteristics of colonies from single HeLa cells with and without a “feeder” layer. Jour. Exp. Med. 103, 273 (1956).

    CAS  Google Scholar 

  270. Ramos-Alvarez, M. and A. B. Sabin: Characteristics of poliomyelitis and other enteric viruses recovered in tissue culture from healthy American children. Proc. Soc. Exp. Biol. Med. 87, 655 (1954).

    PubMed  CAS  Google Scholar 

  271. — Intestinal viral flora of healthy children demonstrable by monkey kidney tissue culture. Am. J. Public Health 46, 295 (1956).

    CAS  Google Scholar 

  272. Randall, Ch. C.: Adaptation of HeLa cells (Gey) to horse serum. Fed. Proc. 14, 416 (1955).

    Google Scholar 

  273. Rappaport, C.: Trypsinization of monkey-kidney tissue: An automatic method for the preparation of cell suspensions. Bull. Wld. Hlth. Org. 14, 147 (1956).

    CAS  Google Scholar 

  274. Reissig, M. and J. L. Melnick: The cellular changes produced in tissue cultures by Herpes B virus correlated with the concurrent multiplication of the virus. Jour. Exp. Med. 101, 341 (1955).

    CAS  Google Scholar 

  275. Reissig, M., D. W. Howes and J. L. Melnick: Sequence of morphological changes in epithelial cell cultures infected with poliovirus. J. Exp. Med. 104, 289 (1956).

    PubMed  Google Scholar 

  276. Rhodes, A. J., W. Wood and D. Duncan: The present place of virus laboratory tests in the diagnosis of poliomyelitis. World Health Organization. Monograph Series No. 26, p. 237 (1955).

    PubMed  CAS  Google Scholar 

  277. Richter, K. M. and N. W. Woodward: A versatile type of perfusion chamber for long term maintenance and direct microscopic observations of tissues in culture. Exp. Cell Res. 9, 585 (1955).

    PubMed  CAS  Google Scholar 

  278. Rightsel, W. A., R. A. Keltsch, F. M. Tekushan and I. W. McLean jr.: Tissue-culture cultivation of cytopathogenic agents from patients with clinical hepatitis. Science 124, 226 (1956)

    PubMed  CAS  Google Scholar 

  279. Rightsel, W. A., P. Schultz, D. Muething and I. W. McLean jr.: Use of vinyl plastic containers in tissue cultures for virus assays. J. Immunol. 76, 464 (1956)

    PubMed  CAS  Google Scholar 

  280. Riordan, J. T., N. Ledinko and J. L. Melnick: Multiplication of poliomyelitis viruses in tissue cultures of monkey testes. II. Direct isolation and typing of strains from human stools and spinal cords in roller tubes. Am. J. Hyg. 55, 339 (1952).

    PubMed  CAS  Google Scholar 

  281. Rivers, T. M., E. Haagen and R. S. Muckenfuss: Development in tissue cultures of the intracellular changes characteristic of vaccinal and herpetic infection. Jour. Exp. Med. 50, 665 (1929)

    CAS  Google Scholar 

  282. Robbins, F. C. and J. F. Enders: Tissue culture techniques in the study of animal viruses. Am. J. Med. Sci. 220, 316 (1950).

    PubMed  CAS  Google Scholar 

  283. Robbins, F. C., J. F. Enders and T. H. Weller: Cytopathogenic effect of poliomyelitis viruses in vitro on human embryonic tissues. Proc. Soc. Exp. Biol. Med. 75, 370 (1950).

    PubMed  CAS  Google Scholar 

  284. Robbins, F. C., J. F. Enders, T. H. Weller and G. L. Florentino: Studies on the cultivation of poliomyelitis viruses in tissue culture. V. The direct isolation and serologie identification of virus strains in tissue culture from patients with non-paralytic and paralytic poliomyelitis. Am. J. Hyg. 54, 286 (1951).

    PubMed  CAS  Google Scholar 

  285. Robbins, F. C., T. H. Weller and J. F. Enders: Studies on the cultivation of poliomyelitis viruses in tissue culture. II. The propagation of the poliomyelitis viruses in roller-tube cultures of various human tissues. J. Immunol. 69, 673 (1952).

    PubMed  CAS  Google Scholar 

  286. Robertson, H. E., K. T. Brunner and J. T. Syverton: Propagation in vitro of poliomyelitis viruses. VII. pH change of HeLa cell cultures for assay. Proc. Soc. Exp. Biol. Med. 88, 119 (1955).

    PubMed  CAS  Google Scholar 

  287. Rose, G.: A separable and multipurpose tissue culture chamber. Texas Rep. Biol. Med. 12, 1074 (1954).

    CAS  Google Scholar 

  288. Rous, P. and F. S. Jones: A method for obtaining suspensions of living cells from the fixed tissues and for the plating out of individual cells. Jour. Exp. Med. 23, 549 (1916).

    CAS  Google Scholar 

  289. Rowe, W. P., R. J. Huebner, L. K. Gilmore, R. H. Parrott and T. G. Ward: Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc. Soc. Exp. Biol. Med. 84, 570 (1953).

    PubMed  CAS  Google Scholar 

  290. Rowe, W. P., R. J. Huebner, J. W. Hartley, T. G. Ward and R. H. Parrott: Studies of the adenoidal-pharyngeal-conjunctival (APC) group of viruses. Am. J. Hyg. 61, 197 (1955).

    Google Scholar 

  291. Rowe, W. P., J. W. Hartley and R. J. Huebner: Additional serotypes of the APC virus group. Proc. Soc. Exp. Biol. Med. 91, 260 (1956).

    PubMed  CAS  Google Scholar 

  292. Rowe, W. P., J. W. Hartley, S. Waterman, H. C. Turner and R. J. Huebner: Cytopathogenic agent resembling human salivary gland virus recovered from tissue cultures of human adenoids. Proc. Soc. Exp. Biol. Med. 92, 418 (1956).

    PubMed  CAS  Google Scholar 

  293. Rubin, H., M. Baluda and J. E. Hotchin: The maturation of western equine encephalomyelitis virus and its release from chick embryo cells in suspension. Jour. Exp. Med. 101, 205 (1955).

    CAS  Google Scholar 

  294. Rustigian, R., P. Johnston and H. Reihart: Infection of monkey kidney tissue cultures with virus-like agents. Proc. Soc. Exp. Biol. Med. 88, 8 (1955).

    PubMed  CAS  Google Scholar 

  295. Sacerdote de Lustig, E. et A. E. Paradi: Action du virus A d’influenza sur la cellule normale et tumorale cultivée in vitro. C. R. Soc. Biol. 146, 612 (1952).

    Google Scholar 

  296. — Action du virus de coxsackie sur le muscle d’embryon de poulet cultivé in vitro. C. R. Soc. Biol. 148, 1648 (1954).

    CAS  Google Scholar 

  297. Sabin, A. B. and P. K. Olitsky: Cultivation of poliomyelitis virus in vitro in human embryonic nervous tissue. Proc. Soc. Exp. Biol. Med. 34, 357 (1936).

    CAS  Google Scholar 

  298. Sabin, A. B.: Noncytopathogenic variants of poliomyelitis viruses and resistance to superinfection in tissue culture. Science 120, 357 (1954).

    PubMed  CAS  Google Scholar 

  299. Sabin, A. B., W. A. Hennessen and J. Winsser: Studies on variants of poliomyelitis virus. I. Experimental segregation and properties of avirulent variants of 3 immunologie types. Jour. Exp. Med. 99, 551 (1954).

    CAS  Google Scholar 

  300. Sabin, A. B.: Insectborne virus diseases of military importance. Military Medicine 116, 245 (1955).

    PubMed  CAS  Google Scholar 

  301. — Recent advances in our knowledge of dengue and sandfly fever. Am. J. Trop. Med. a. Hyg. 4, 198 (1955).

    CAS  Google Scholar 

  302. — Characteristics and genetic potentialities of experimentally produced and naturally occuring variants of poliomyelitis virus. Ann. New York Acad. Sci. 61(Art. 4), 924 (1955).

    CAS  Google Scholar 

  303. Salk, J. E.: Studies in human subjects on active immunization against poliomyelitis. J. Am. Med. Ass. 151, 1081 (1953).

    CAS  Google Scholar 

  304. Salk, J. E., J. S. Youngner and E. N. Ward: Use of colorchange of phenol red as the indicator in titrating poliomyelitis virus or its antibody in a tissue-culture system. Am. J. Hyg. 60, 214 (1954).

    PubMed  CAS  Google Scholar 

  305. Sanders, M.: Studies on the cultivation of the virus of lymphogranuloma venerum. Jour. Exp. Med. 71, 113 (1940).

    CAS  Google Scholar 

  306. Sanders, M. and E. Molloy: Cultivation of virus of equine encephalomyelitis in serum ultrafiltrate and buffered salt solutions (Simms). Proc. Soc. Exp. Biol. Med. 45, 327 (1940).

    Google Scholar 

  307. Sanders, M. and C. W. Jungeblut: Studies in rodent poliomyelitis. II. Cultivation of the murine strain of SK poliomyelitis virus. Jour. Exp. Med. 75, 631 (1942).

    CAS  Google Scholar 

  308. Sanders, M. and R. C. Alexander: Epidemic keratoconjunctivitis. I. Isolation and identification of a filterable virus. Jour. Exp. Med. 77, 71 (1943).

    CAS  Google Scholar 

  309. Sanders, M., I. Kiem and D. Lagunoff: Cultivation of viruses. Arch. Path. 56, 148 (1953).

    CAS  Google Scholar 

  310. Sanford, K. K., W. R. Earle and G. D. Likely: The growth in vitro of single isolated tissue cells. J. Nat. Cancer Inst. 9, 229 (1948).

    PubMed  CAS  Google Scholar 

  311. Sanford, K. K., W. R. Earle, V. J. Evans, H. K. Waltz and J. E. Shannon: The measurement of proliferation in tissue cultures by enumeration of cell nuclei. J. Nat. Cancer Inst. 11, 773 (1951).

    PubMed  CAS  Google Scholar 

  312. Scherer, W. F.: Agglutination of a pure strain of mammalian cells (L strain, Earle) by suspensions of vaccinia virus. Proc. Soc. Exp. Biol. Med. 80, 598 (1952).

    PubMed  CAS  Google Scholar 

  313. Scherer, W. F. and J. T. Syverton: Studies on the propagation in vitro of poliomyelitis viruses. II. A description of the growth curve and its relation to the cytopathogenicity of poliomyelitis virus. Jour. Exp. Med. 96, 369 (1952).

    Google Scholar 

  314. — Studies on the propagation in vitro of poliomyelitis viruses. III. The propagation of poliomyelitis viruses in tissue cultures devoid of nerve cells. Jour. Exp. Med. 96, 389 (1952).

    Google Scholar 

  315. Scherer, W. F.: Hostcell-virus relationship in vitro studied with a pure strain of mammalian cell (L strain, Earle). Fed. Proc. 12, 401 (1953).

    Google Scholar 

  316. — The utilization of a pure strain of mammalian cells (Earle) for the cultivation of viruses in vitro. I. Multiplication of pseudo-rabies and herpes simplex viruses. Am. J. Path. 29, 113 (1953).

    PubMed  CAS  Google Scholar 

  317. Scherer, W. F., J. T. Syverton and G. O. Gey: Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix. Jour. Exp. Med. 97, 695 (1953).

    CAS  Google Scholar 

  318. Scherer, W. F. and J. T. Syverton: The viral range in vitro of a malignant human epithelial cell (strain HeLa, Gey). I. Multiplication of herpes simplex, pseudo-rabies and vaccinia virus. Am. J. Path. 30, 1057 (1954).

    PubMed  CAS  Google Scholar 

  319. — The viral range in vitro of a malignant human epithelial cell (strain HeLa, Gey). II. Studies with encephalitis viruses of the eastern, western, West Nile, St. Louis and Japanese B Types. Am. J. Path. 30, 1075 (1954).

    PubMed  CAS  Google Scholar 

  320. Scherer, W. F. and A. C. Hoogasian: Preservation at subzero temperatures of mouse fibroblasts (strain L) and human epithelial cells (strain HeLa). Proc. Soc. Exp. Biol. Med. 87, 480 (1954).

    PubMed  CAS  Google Scholar 

  321. Scherer, W. F.: Studies on the propagation in vitro of poliomyelitis viruses. VI. Effect on virus yield of cell population, virus inoculum and temperature of incubation. J. Immunol. 73, 331 (1954).

    PubMed  CAS  Google Scholar 

  322. — Comparative susceptibility of cells of the same type to infection by poliomyelitis virus. Ann. New York Acad. Sci. 61(Art. 4), 806 (1955).

    CAS  Google Scholar 

  323. Scherer, W. F. and J. T. Syverton: The viral range in vitro of a malignant human epithelial cell (strain HeLa, Gey). III. Studies with pseudo-lymphocytic choriomeningitis virus. General discussion. Am. J. Path. 31, 31 (1955).

    PubMed  CAS  Google Scholar 

  324. Schilling, E. L., W. R. Earle and V. J. Evans: Use of perforated cellophane substrate in slide preparation tissue cultures. J. Nat. Cancer Inst. 10, 883 (1950).

    PubMed  CAS  Google Scholar 

  325. Schultz, E. W. and G.F. Williams: Cultivation of rabies virus. Proc. Soc. Exp. Biol. Med. 37, 372 (1937).

    Google Scholar 

  326. Shannon, J. E. and W. R. Earle: Qualitative comparison of the growth of chick-heart and strain L fibroblasts planted as suspensions on pyrex glass and perforated cellophane substrates. J. Nat. Cancer Inst. 12, 155 (1951).

    PubMed  Google Scholar 

  327. Shannon, J. E., W. R. Earle and H. K. Waltz: Massive tissue cultures prepared from whole chick embryos planted as a cell suspension on glass substrate. J. Nat. Cancer Inst. 13, 349 (1952).

    PubMed  Google Scholar 

  328. Shaw, M.: Cultivation of Coxsackie virus in embryonated eggs and in chick tissue cultures. Proc. Soc. Exp. Biol. Med. 79, 718 (1952).

    Google Scholar 

  329. Shean, D. B. and E. M. Schultz: Comparative tissue expiant requirements of Columbia-SK, C (M) and MM viruses and of Theiler’s encephalomyelitis virus. Proc. Soc. Exp. Biol. Med. 73, 622 (1950).

    PubMed  CAS  Google Scholar 

  330. Shih-Man, Chang R.: Continous subcultivation of epithelial-like cells from normal human tissues. Proc. Soc. Exp. Biol. Med. 87, 440 (1955).

    Google Scholar 

  331. Sickles, G. M., P. Feorino and H. Plager: Isolation and type determination of Coxsackie virus, group B, in tissue culture. Proc. Soc. Exp. Biol. Med. 88, 22 (1955).

    PubMed  CAS  Google Scholar 

  332. Sickles, G. M., M. Mutterer, P. Feorino and H. Plager: Recently classified types of Coxsackie virus, group A. Behavior in tissue culture. Proc. Soc. Exp. Biol. Med. 90, 529 (1955).

    PubMed  CAS  Google Scholar 

  333. Simms, H. S. and N. P. Stillman: Substances affecting adult tissue in vitro. I. The stimulating action of trypsin on fresh adult tissues. J. Gen. Physiol. 20, 603 (1937).

    PubMed  CAS  Google Scholar 

  334. Simms, H. S. and M. Sanders: Use of serum ultrafiltrate in tissue cultures for studying deposition of fat and for propagation of viruses. Arch. Path. 33, 619 (1942).

    CAS  Google Scholar 

  335. Slater, E. A. and J. T. Syverton: The cultivation of Coxsackie virus. Proc. Soc. Exp. Biol. Med. 74, 509 (1950).

    PubMed  CAS  Google Scholar 

  336. Smith, M. G.: Propagation in tissue cultures of a cytopathogenic virus from human salivary gland virus (SGV) disease. Proc. Soc. Exp. Biol. Med. 92, 424 (1956).

    PubMed  CAS  Google Scholar 

  337. Smith, W., V. C. Chambers and C. A. Evans: Growth of neurotropic viruses in extraneural tissues. Preliminary report on the propagation of poliomyelitis virus (Lansing and Hof strains) in cultures of human testicular tissue. Northwest Med. (Seattle) 49, 368 (1950).

    CAS  Google Scholar 

  338. — Growth of neurotropic viruses in extraneural tissues. IV. Poliomyelitis virus in human testicular tissue in vitro. Proc. Soc. Exp. Biol. Med. 76, 696 (1951).

    PubMed  CAS  Google Scholar 

  339. Smith, W. M. and C. A. Evans: Growth of neurotropic viruses in extraneural tissues. VII. Cultivation of MM and western equine encephalitis viruses in cultures of rhesus testicular tissue. J. Immunol. 72, 353 (1954).

    PubMed  CAS  Google Scholar 

  340. Smorodintseff, A. A.: The spring-summer tick-borne encephalitis. Arch. Virusforschung 1, 468 (1940).

    Google Scholar 

  341. Sosa-Martïnez, J., L. Guitierrez-Villegas and R. M. Sosa: Propagation of herpes simplex virus in tissue cultures of rabbit kidney. J. Bact. 70, 391 (1955).

    PubMed  Google Scholar 

  342. Southam, C. S. and V. I. Babcock: Propagation of Bunyamwera, West Nile, Ilheus and Br. I viruses in human cells in tissue culture. Proc. Soc. Exp. Biol. Med. 86, 180 (1954).

    PubMed  CAS  Google Scholar 

  343. Steigman, A. J., U. P. Kokko and R. J. Silverberg: Mack virus. Serum and gamma globulin neutralization of unidentified agent isolated from suspected nonparalytic poliomyelitis. Proc. Soc. Exp. Biol. Med. 83, 200 (1953).

    PubMed  CAS  Google Scholar 

  344. Stoler, M. and M. K. Gey: Destruction of a human fibrosarcoma strain (AFi) in tissue cultures following the growth of poliomyelitis viruses: A preliminary report. Bull. Johns Hopkins Hospital 92, 385 (1953).

    CAS  Google Scholar 

  345. Stulberg, C. S., R. Schapira and C. R. Eidam: Virus growth in tissue culture fibroblasts. II. Coxsackie virus (group B) in cultures of mouse fat tissue. Proc. Soc. Exp. Biol. Med. 81, 642 (1952).

    PubMed  CAS  Google Scholar 

  346. Stulberg, C. S. and R. Schapira: Virus growth in tissue culture fibroblasts. I. Influenza A and herpes simplex viruses. J. Immunol. 70, 51 (1953).

    PubMed  CAS  Google Scholar 

  347. Stulberg, C. S., R. Schapira and C. R. Eidam: Comparative characteristics of two Coxsackie viruses in tissue culture. J. Immunol. 72, 107 (1954).

    PubMed  CAS  Google Scholar 

  348. Stulberg, C. S., L. Berman and F. H. Ruddle: Detroit-6 strain of human epithelial-like cells: virus susceptibilities. Proc. Soc. Exp. Biol. Med. 89, 438 (1955).

    PubMed  CAS  Google Scholar 

  349. Svedmyr, A., J. F. Enders and A. Holloway: Complement fixation with Brunhilde and Lansing poliomyelitis viruses propagated in tissue culture. Proc. Soc. Exp. Biol. Med. 79, 296 (1952).

    PubMed  CAS  Google Scholar 

  350. — Complement fixation with the three types of poliomyelitis viruses propagated in tissue culture. Am. J. Hyg. 57, 60 (1953).

    PubMed  CAS  Google Scholar 

  351. Swim, H. E. and R. F. Parker: Method for establishing human cells in culture: Susceptibility to poliomyelitis after prolonged cultivation. Proc. Soc. Exp. Biol. Med. 83, 577 (1953).

    PubMed  CAS  Google Scholar 

  352. — Nonbicarbonate buffers in cell culture media. Science 122, 466 (1955).

    PubMed  CAS  Google Scholar 

  353. — Preservation of cell cultures at 4° C. Proc. Soc. Exp. Biol. Med. 89, 549 (1955).

    PubMed  CAS  Google Scholar 

  354. Symposium on the laboratory propagation and detection of the agent of hepatitis. New York, March 31st. (1954).

    Google Scholar 

  355. Syverton, J. T., W. F. Scherer and G. Butorac: Propagation of poliomyelitis virus in cultures of monkey and human testicular tissues. Proc. Soc. Exp. Biol. Med. 77, 23 (1951).

    PubMed  CAS  Google Scholar 

  356. Syverton, J. T. and W. F. Scherer: Studies on the propagation in vitro of poliomyelitis viruses. I. Viral multiplication in tissue cultures employing monkey and human testicular cells. Jour. Exp. Med. 96, 355 (1952).

    Google Scholar 

  357. — Studies on the propagation in vitro of poliomyelitis viruses. V. The application of strain HeLa human epithelial cells for isolation and typing. J. Lab. a. Clin. Med. 43, 286 (1954).

    CAS  Google Scholar 

  358. Takemori, N., M. Nakano, M. Hemmi, H. Ikeda, S. Yanagida and M. Kitaoka: Destruction of tumor cells by Rift Valley fever virus. Nature 174, 698 (1954).

    PubMed  CAS  Google Scholar 

  359. Takemori, N., M. Nakano, M. Hemmi and M. Kitaoka: Propagation of Rift Valley fever virus in ascites hepatoma cells of the rat: production of a new variant of the virus. Virology 1, 58 (1955).

    PubMed  CAS  Google Scholar 

  360. Takemori, N., M. Nakano and M. Hemmi: Plaque formation with Rift Valley fever virus. Virology 1, 250 (1955).

    PubMed  CAS  Google Scholar 

  361. Takemoto, K. K., R. K. Lynt, W. P. Rowe, R. J. Huebner, J. A. Bell, G. W. Mellin and D. J. Davis: Primary isolation of influenza A, B and C viruses in monkey kidney tissue cultures. Proc. Soc. Exp. Biol. Med. 89, 308 (1955).

    PubMed  CAS  Google Scholar 

  362. Taylor, C. E.: Interference between influenza and equine encephalitis viruses in tissue culture. J. Immunol. 71, 125 (1953).

    PubMed  CAS  Google Scholar 

  363. Theiler, M., and H. H. Smith: The effect of prolonged cultivation in vitro upon the pathogenicity of yellow fever virus. Jour. Exp. Med. 65, 767 (1937).

    CAS  Google Scholar 

  364. Thicke, J. C., D. Duncan, W. Wood, A. E. Franklin and A. J. Rhodes: Cultivation of poliomyelitis virus in tissue culture. I. Growth of the Lansing strain in human embryonic tissue. Canad. J. Med. Sci. 30, 231 (1952).

    CAS  Google Scholar 

  365. Thompson, R. L. and M. S. Coates: The effect of temperature upon the growth and survival of myxoma, herpes and vaccinia viruses in tissue culture. J. Infect. Dis. 71, 83 (1942).

    Google Scholar 

  366. Toolan, H. W. and A. E. Moore: Oncolytic effect of Egypt virus on a human epidermoid carcinoma grown in X-irradiated rats. Proc. Soc. Exp. Biol. Med. 79, 697 (1952).

    PubMed  CAS  Google Scholar 

  367. Tyrrell, D. A. J.: New tissue culture systems for influenza, Newcastle disease and vaccinia virus. J. Immunol. 74, 293 (1955).

    PubMed  CAS  Google Scholar 

  368. Ulloa-Gregori, O., T. G. Blocker, W. W. Nowinski and C. M. Pomerat: The effect of ascitic fluid and of blood serum on the outgrowth of epidermal cells from the human skin in tissue culture. Texas Rep. Biol. a. Med. 8, 400 (1950).

    CAS  Google Scholar 

  369. Vogelaar, J. P. M. and E. Erlichman: Contributions to tissue culture technic. Am. J. Cancer 35, 510 (1939).

    Google Scholar 

  370. Warren, J., R. G. Wittler and M. Vincent: The cultivation of tissues in small sealable dishes. J. Lab. a. Clin. Med. 46, 144 (1955).

    CAS  Google Scholar 

  371. Watson, B. K.: Distribution of mumps virus in tissue cultures as determined by fluorescein-labeled antiserum. Proc. Soc. Exp. Biol. Med. 79, 222 (1952).

    PubMed  CAS  Google Scholar 

  372. Watson, B. K. and F. S. Cheever: Further studies on the behaviour of mumps virus in Maitland type of tissue cultures. J. Immunol. 75, 161 (1955).

    PubMed  CAS  Google Scholar 

  373. Webster, L. T. and A. D. Clow: Propagation of rabies virus in tissue culture. Journ. Exp. Med. 66, 125 (1937).

    CAS  Google Scholar 

  374. Webster, L. T. and M. S. Johnson: Comparative virulence of St. Louis encephalitis virus cultured with brain tissue from innately susceptible and innately resistant mice. Jour. Exp. Med. 74, 489 (1941).

    CAS  Google Scholar 

  375. Weinstein, H. J., C. Alexander, G. M. Yoshihara and W. M. M. Kirby: Preparation of human amnion tissue cultures. Proc. Soc. Exp. Biol. Med. 92, 535 (1956).

    PubMed  Google Scholar 

  376. Weller, T. H. and J. F. Enders: Production of hemagglutinin by mumps and influenza A viruses in suspended cell tissue cultures. Proc. Soc. Exp. Biol. Med. 69, 124 (1948).

    PubMed  CAS  Google Scholar 

  377. Weller, T. H., F. C. Robbins and J. F. Enders: Cultivation of poliomyelitis virus in cultures of human foreskin and embryonic tissues. Proc. Soc. Exp. Biol. Med. 72, 153 (1949).

    PubMed  CAS  Google Scholar 

  378. Weller, T. H. and M. B. Stoddard: Intranuclear inclusion bodies in cultures of human tissue inoculated with varicella vesicle fluid. J. Immunol. 68, 311 (1952).

    PubMed  CAS  Google Scholar 

  379. Weller, T. H., J. F. Enders, F. C. Robbins and M. B. Stoddard: Studies on the cultivation of poliomyelitis viruses in tissue culture. I. The propagation of poliomyelitis viruses in suspended cell cultures of various human tissues. J. Immunol. 69, 645 (1952).

    PubMed  CAS  Google Scholar 

  380. Weller, T. H., F. C. Robbins and M. B. Stoddard: Cultivation of Coxsackie viruses in human tissues. Fed. Proc. 11, 486 (1952).

    Google Scholar 

  381. Weller, T. H., F. C. Robbins, M. B. Stoddard and G. L. Florentino: Propagation of Coxsackie viruses in cultures of human tissues. J. Immunol. 71, 92 (1953).

    PubMed  CAS  Google Scholar 

  382. Weller, T. H.: The application of tissue-culture methods to the study of poliomyelitis. New Engl. J. Med. 249, 186 (1953).

    PubMed  CAS  Google Scholar 

  383. — Serial propagation in vitro of agents producing inclusion bodies derived from varicella and herpes zoster. Proc. Soc. Exp. Biol. Med. 83, 340 (1953).

    PubMed  CAS  Google Scholar 

  384. — The diagnosis of virus infections employing tissue culture methods. In “The dynamics of virus and rickettsial infections”. New York, Blakiston (1954).

    Google Scholar 

  385. Weller, T. H. and A. H. Coons: Fluorescent antibody studies with agents of varicella and herpes zoster propagated in vitro. Proc. Soc. Exp. Biol. Med. 86, 789 (1954).

    PubMed  CAS  Google Scholar 

  386. Wenner, H. A. and C. A. Miller: Comparison of methods for recovering poliomyelitis viruses from human sources. Proc. Soc. Exp. Biol. Med. 86, 11 (1954).

    PubMed  CAS  Google Scholar 

  387. Wenner, H. A.: Some comparative observation on the behaviour of poliomyelitis viruses in animals and in tissue cultures. Ann. New York Acad. Sci. 61(Art. 4), 840 (1955).

    CAS  Google Scholar 

  388. White, P. R.: Cultivation of animal and plant cells. 1954. New York, The Ronald Press Comp.

    Google Scholar 

  389. Winkel, R., GmbH, Göttingen: Schrifttumverzeichnis zur Phasenkontrast-mikroskopie. Druckschrift ZW 511-S, Juni 1954.

    Google Scholar 

  390. Wirth, J.: La culture des virus in vitro. In Levadi, G. et P. Lépine: Les ultravirus des maladies humaines. 2 ed. Paris, Librairie Maloine (1948).

    Google Scholar 

  391. Wood, W., A. E. Franklin, E. M. Clark, D. Duncan and A. J. Rhodes: Cultivation of poliomyelitis virus in tissue culture. III. Synthetic medium in roller tube cultures. Proc. Soc. Exp. Biol. Med. 81, 434 (1952).

    PubMed  CAS  Google Scholar 

  392. Wood, W. and F. T. Shimada: Isolation of strains of virus B from tissue cultures of cynomolgus and rhesus kidney. Canad. J. Publ. Health 45, 509 (1954).

    CAS  Google Scholar 

  393. Woolridge, R. L., J. T. Grayston, J. E. Whiteside, C. G. Loosli, M. Friedman and W. E. Pierce: Studies on acute respiratory illness in naval recruits, with emphasis on the adenoviruses (APC-RI). J. Infect. Dis. 99, 182 (1956).

    PubMed  Google Scholar 

  394. Yanamura, H. Y. and K. F. Meyer: Studies on the virus of psittacosis cultivated in vitro. J. Infect. Dis. 68, 1 (1941).

    Google Scholar 

  395. Youngner, J. S., E. N. Ward and J. E. Salk: Studies on poliomyelitis viruses in cultures of monkey testicular tissue. I. Propagation of virus in roller tubes. Am. J. Hyg. 55, 291 (1952).

    PubMed  CAS  Google Scholar 

  396. — Studies on poliomyelitis viruses in cultures of monkey testicular tissue. II. Differences among strains in tissue culture infectivity with preliminary data on the quantitative estimation of virus and antibody. Am. J. Hyg. 55, 301 (1952).

    PubMed  CAS  Google Scholar 

  397. Youngner, J. S.: Monolayer tissue cultures. I. Preparation and standardization of suspensions of trypsin-dispersed monkey kidney cells. Proc. Soc. Exp. Biol. Med. 85, 202 (1954).

    PubMed  CAS  Google Scholar 

  398. — Monolayer tissue cultures. II. Poliomyelitis virus assay in roller tube cultures of trypsin-dispersed monkey kidney. Proc. Soc. Exp. Biol. Med. 85, 527 (1954).

    PubMed  CAS  Google Scholar 

  399. — Monolayer tissue cultures. III. Propagation of poliomyelitis viruses in cultures of trypsin-dispersed monkey kidney cells. J. Immunol. 73, 392 (1954).

    PubMed  CAS  Google Scholar 

  400. — Virus yield per cell in monkey kidney cultures inoculated with different strains of poliomyelitis virus. J. Immunol. 76, 50 (1956).

    PubMed  CAS  Google Scholar 

  401. — Virus adsorption and plaque formation in monolayer cultures of trypsin-dispersed monkey kidney. J. Immunol. 76, 288 (1956).

    PubMed  CAS  Google Scholar 

  402. Zinsser, H. and E. B. Schoenbach: Studies on the physiological conditions prevailing in tissue cultures. Jour. Exp. Med. 66, 207 (1937).

    CAS  Google Scholar 

  403. Zinsser, H., F. Fitz Patrick and H. Wei: A study of rickettsiae grown on agar tissue cultures. Jour. Exp. Med. 69, 179 (1939).

    CAS  Google Scholar 

  404. Zitger, E. M., J. Fogh and T. H. Dunnebacke: Human amnion cells for large scale production of poliomyelitis virus. Science 122, 30 (1955).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratorium der Stiftung zur Erforschung der spinalen Kinderlähmung und Neurologische Universitätsklinik, Hamburg-Eppendorf, Deutschland

    Wilhelm Klöne

Authors
  1. Wilhelm Klöne
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Bern, Switzerland

    C. Hallauer

  2. San Francisco, USA

    K. F. Meyer

Rights and permissions

Reprints and permissions

Copyright information

© 1958 Springer-Verlag Wien

About this chapter

Cite this chapter

Klöne, W. (1958). Der Nachweis menschenpathogener Virusarten mittels der Gewebekultur. In: Hallauer, C., Meyer, K.F. (eds) Handbuch der Virusforschung. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7885-0_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-7885-0_6

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7886-7

  • Online ISBN: 978-3-7091-7885-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation