Abstract
The shortage of human donor organs for transplantation has induced a resurgence of interest in xenotransplantation. For this approach vascularized transplants (heart, kidney, liver) and tissue (islet cells) are considered [1]. Moreover, it became clear that HIV infection cannot be controlled by classical ways of treatment modalities. Hematopoiesis from animal donors resistent to HIV, which would allow human survival, is a fascinating indication for xenotransplantation to humans [8].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Auchincloss H (1988) Xenogeneic transplantation. A review. Transplantation 45: 1–20
Bach FH, Blakely ML, Van der Werft WJ, Vanhove B, Stuhlmeier K, de Martin R, Winkler H (1994) Xenotransplantation: problems posed by endothelial cell activation. Transplant Proc 26: 1029–1030
Langford GA, Yannoutsos N, Cozzi E, Lancaster R, Elsome K, Chen P, Richards A, White DJG (1994) Production of pigs transgenic for human decay accelarating factor. Transplant Proc 26: 1400–1401
Loveland BE, Syokolai K, Johnstone RW, McKenzie IFC (1994) Coordinate functions of multiple complement regulating molcules, CD46, CD5 5, and CD59-Transplant Proc 26: 1070–1071
Panzer S, Geller RL, Bach FH (1990) Purified human T cells stimulated with cross-linked anti-CD3 monoclonal antibody OKT/3:rIL-l is a co-stimulatory factor for CD4+CD29+CD45RA-T cells. Scand J Immunol 32: 359–371
Panzer S, Madden M, Matsuki K (1993) Interaction of IL-l(3, IL-6 and tumor necrosis factor-alpha ( TNF-OC) in human T cells activated by murine antigens. Clin Exp Immunol 93: 471–478
Piatt JL, Vercerlotti GM, Dalmasso AP, Mata AJ, Bolman RM, Najarian JS, Bach FH (1990) Transplantation of discordant xenografts: a review of progress. Immunology today 11: 450–57
Ricordi C, Tzakis AG, Rybka WB, Fontes P, Ball ED, Trucco M, Kocova M, Triulzi D, McMichael J, Dozle H, Gupta P, Fung JJ, Starzl TE (1994) Xenotransplantation of hematopietic cells resistent to HIV as a potential treatment for patients with AIDS. Transplant Proc 26: 1302–1303
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag/Wien
About this chapter
Cite this chapter
Panzer, S. (1995). Tolerance is a condition sine qua non in life: its relation to transplantation. In: Kleinberger, G., Lenz, K., Ritz, R., Schuster, HP., Stockenhuber, F. (eds) Transplantation. Intensivmedizinisches Seminar, vol 8. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7678-8_7
Download citation
DOI: https://doi.org/10.1007/978-3-7091-7678-8_7
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82648-5
Online ISBN: 978-3-7091-7678-8
eBook Packages: Springer Book Archive