Translation of cytoskeletal interactions and assembly/disassembly processes into useful activities such as cell translocation, shape changes, adhesion, or contact formation requires physical connections between the cytoskeleton and the plasma membrane. Because of their fundamental importance, associations between membranes and the cytoskeleton have been intensely studied in the past decade. A specific impetus was the discovery in many cell types of proteins related to the cytoskeleton of the erythrocyte, a cell that has long been a useful model for the study of cell membranes. This section examines the basic principles of membrane-cytoskeleton interactions from a general perspective; details of all the relevant model systems can not be considered here.
KeywordsActin Filament Intermediate Filament Brush Border Integral Membrane Protein Adherens Junction
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