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Brain Edema pp 569-589 | Cite as

Fine Structure of Cerebral Fluid Accumulation

X. A Review of Experimental Edema in White Matter
  • Asao Hirano
  • H. M. Zimmerman
  • Seymour Levine

Abstract

Although cerebral edema has been studied for many years, conclusive evidence as to the precise origin, location and morphological nature of the edema fluid had to await both the advent of the electron microscope and improved techniques of preservation. The development of better techniques has permitted us to carry out a series of studies which, we feel, provide some information clarifying the edema process. Edema is a condition which affects primarily white matter. Therefore, in our experiments we studied several different types of white matter injury. One type of injury followed implantation into the brain of the relatively bland polysaccharide isolated from Cryptococcus neoformans. Another type of injury followed implantation of the powerfully necrotizing chemical agent, silver nitrate. A third type of injury was of systemic, auto-immune origin, that is, experimental allergic encephalomyelitis (EAE).

Keywords

White Matter Silver Nitrate Cerebral Edema Experimental Allergic Encephalomyelitis Edema Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1967

Authors and Affiliations

  • Asao Hirano
  • H. M. Zimmerman
  • Seymour Levine

There are no affiliations available

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