Brain Edema pp 249-258 | Cite as

Morphological Substrate of the Blood-Brain Barrier in Human Brain Tumors

  • K. A. Hossmann


It is a well-established fact that in human brain tumors the so-called blood-brain barrier system is severely affected. This has been proved by the use of indicator substances such as dyes (3, 6) or radioactive isotopes (2, 19, 25). Gamma-encephalography, a current diagnostic method, is based on this principle (25).


Malignant Glioma Collagen Fibril Normal Brain Tissue Perivascular Space Human Brain Tumor 
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© Springer-Verlag New York Inc. 1967

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  • K. A. Hossmann

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