Advertisement

Asthma pp 104-114 | Cite as

Bronchial asthma. Definition and prognosis

  • H. Matthys
  • C. Kroegel
  • Chr. Virchow
Conference paper

Summary

Prof. H. Matthys attempts to define the “asthmatic disorder” during the life span of the patient. He points out the more less well defined differences between several forms of asthma and COPD also concerning the natural course and consequences of therapeutic regimes. The author also refers to previous contributions on this subject during this sympo­sium, and thus creates a timely synopsis. He emphasizes the need of taking a reliable history of the patient, exact investigation and definition of the functional disorder, and all this taken together as the basis for consequent treatment.

Keywords

Chronic Obstructive Pulmonary Disease Airway Obstruction Airway Inflammation Chronic Bronchitis Nasal Polyp 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Bronchialasthma: Definition und Prognose

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Agosti M, Sprenger ID, Lum IG, Wilherspoon RP, Fischer LD, Hendersen WR (1988) Transfer of allergen specific IgE mediated hypersensitivity with allogenic bone marrow transplantation. N Engl J Med 319: 1623PubMedCrossRefGoogle Scholar
  2. 2.
    American Thoracic Society (1987) Chronic bronchitis asthma and pulmonary emphysema. Am Rev Respir Dis 136: 224–225Google Scholar
  3. 3.
    Curschmann H (1883) Bronchiolitis exsudativa und ihr Verhältnis zum Asthma nervosum. Dtsch Arch KIM Med 32: 1Google Scholar
  4. 4.
    Ehrlich P (1979) Über die spezifischen Granulationen des Blutes. Arch Anat Physiol 3: 571Google Scholar
  5. 5.
    Kroegel C (1992) Mechanisms of chronic inflammation. The eosinophil leucocyte as effector cell in the pathogenesis of inflammatory disease, its phenotypical and functional properties and modulation by cytokines. Habilitation Thesis, FreiburgGoogle Scholar
  6. 6.
    Kroegel C, Virchow C jr, Matthys H (1993) Cell biology and effector functions of the eosinophil leucocyte in bronchial asthma. In: Kummer F (ed) Asthma–Immunopathology and Immunotherapy/Immunopathologie und Immunotherapie. Wien, New York: Springer, pp 34–54Google Scholar
  7. 7.
    Matthys H, Herceg R, Eltschka R (1989) Is hyperreactivity correlated with the degree of airway inflammation? Intrinsic Asthma, Agents and Agents [Suppl] 28: 225–231Google Scholar
  8. 8.
    Matthys H (1979) Inhalative provocation test — when is it positive? Scand J Resp Dis [Suppl] 103: 208–211Google Scholar
  9. 9.
    Matthys H, Vastag E, Köhler D, Daikeler G, Fischer J (1983) Mucociliaiy clearance in patients with chronic bronchitis and bronchial carcinoma, Respiration 44: 329–337PubMedCrossRefGoogle Scholar
  10. 10.
    Matthys H (1990) Definition and assessment of asthma. Lung [Suppl] 1: 51–56CrossRefGoogle Scholar
  11. 11.
    International Consensus Report on Diagnosis and Treatment of Asthma National Heart Lung, and Blood Institute, NIH Publication No 92–3091 March 1992Google Scholar
  12. 12.
    Schatz M, Harden K, Forsyth A et al (1988) The course of asthma during pregmancy post partum and with successive pregnancies: A prospective analysis. J Allergy Clin Immunol 81: 509–517Google Scholar
  13. 13.
    Schmidt W, Flech K (1992) Haben operative Maßnahmen im Hals-RachenRaum einen Einfluß auf den Verlauf des Asthma bronchiale? Atemw-Lungenkrkh 18: 66–74Google Scholar
  14. 14.
    Sears MR, Taylor DR, Pruit CG, Lake DC, Li Q, Flannery EM, Yates DE, Lucas MK, Herbison GP (1990) Regular inhaled beta-agonist treatment in bronchial asthma. Lancet 336: 1391–1396PubMedCrossRefGoogle Scholar
  15. 15.
    Spitzer WO, Suissa S, Ernst P, Horwitz RI, Habbick B, Cockcroft D et al (1992) The use of (β-agonists and the risk of death and near death from asthma. N Engl J Med 326 (8): 501–506PubMedCrossRefGoogle Scholar
  16. 16.
    Vastag F, Matthys H, Köhler D, Gronbeck L, Daikeler G (1985) Mucociliary clearance and airway obstruction in smokers, ex smokers and normal subjects who never smoked. Eur J Respir Dis 66: 93–100Google Scholar
  17. 17.
    Virchow C jr, Hoelscher U, Hage U, Kortsik C, Kroegel C, Virchow C sen, Matthys H (1993) Die Konzentration von Eosinophilem Cationischen Protein (ECP) im Sputum von Patienten mit Asthma korreliert mit Lungenfunktionsparametern. Pneumol (in press)Google Scholar
  18. 18.
    Virchow JC jr, Boer L, Bode E, Hansel TT, Bloser K, Walker C (1992) Redistribution from naive CD45RA to memory CD45RO T helper cells and evidence for differential V-Beta T cell receptor usage in nonallergic asthma. ARRD 145: A21Google Scholar
  19. 19.
    Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC jr (1992) Allergic and nonallergic asthmatics have distinct patterns of T cell activation and cytokine production in peripheral blood and BAL. ARRD 146: 109–115Google Scholar

Copyright information

© Springer-Verlag/Wien 1993

Authors and Affiliations

  • H. Matthys
    • 1
  • C. Kroegel
    • 1
  • Chr. Virchow
    • 1
  1. 1.Division of Pneumology, Department of Internal MedicineUniversity Hospital FreiburgFederal Republic of Germany

Personalised recommendations