Travel-related vector-borne virus infections in Germany
Laboratory diagnosis of imported, vector-borne virus diseases during a 22-month-period in Munich, Germany, is summarized. In 13/317 Germans returning from the Mediterranean with suspected sandfly fever, acute sandfly fever, serotype Toscana, was confirmed serologically: 84.6% of the infections were acquired in Italy. Of 249 German tourists with febrile disease returning from the tropics, acute infection with dengue virus was diagnosed serologically in 26 (10.4%): most infections were acquired in Thailand (57.7%). In a seroepidemiological study of 670 German aid workers who had spent two years in the tropics, 49 (7.3%) were positive for antibodies to dengue, 9 (1.3%) to Chikungunya, and 1 (0.1%) to Sindbis virus. Of 17 Middle Eastern patients with suspected viral haemorrhagic fever, genomic Crimean-Congo haemorrhagic fever virus RNA was amplified in 4 (23.5%) by semi-nested reverse transcriptase polymerase chain reaction, and confirmed by molecular characterization of nucleic acid. With the increase in travel to and from endemic areas, imported vector-borne virus infections are increasingly important in Germany.
KeywordsDengue Virus Dengue Fever Haemorrhagic Fever Dengue Haemorrhagic Fever Chikungunya Virus
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- 2.Burney MI, Ghafoor A, Saleen M, Webb PA, Casals J (1976) Nosocomial outbreak of viral hemorrhagic fever caused by Crimean hemorrhagic fever-Congo virus in Pakistan, January 1976. Am J Trop Med Hyg 29: 941–947Google Scholar
- 4.Butenko AM, Chumakov MP (1990) Isolation of Crimean-Congo hemorrhagic fever virus from patients and from autopsy specimens. Arch Virol [Suppl] 1: 295–301Google Scholar
- 6.Centers for Disease Control and Prevention (1981) Imported dengue-United States, 1990. Morb Mort Wkly Rep 40: 519–520Google Scholar
- 7.Centers for Disease Control and Prevention (1993) Imported dengue-United States, 1991. Dengue Surveill Summ 66: 1–4Google Scholar
- 8.Centers for Disease Control and Prevention (1984) Dengue fever among U.S. military personnel-Haiti, September-November, 1994. Morb Mort Wkly Rep 43: 845–848Google Scholar
- 9.Centers for Disease Control and Prevention (1995) Imported dengue-United States, 1993–1994. Morb Mort Wkly Rep 44: 353–356Google Scholar
- 18.Hayes CG, O’Rourke TF, Fogelman V, Leavengood DD, Crow G, Albersmeyer MM (1989) Dengue fever in American military personnel in the Philippines: clinical observations on the hospitalized patients during a 1984 epidemic. Southeast Asian J Trop Med Pub Health 20: 1–8Google Scholar
- 23.Nicoletti L, Verani P, Caciolli S, Ciufolini MG, Renzi A, Bartolozzi D, Paci P, Leoncini F, Padovani P, Traini E, Baldereschi M, Balducci M (1991) Central nervous system involvement during infection by phlebovirus Toscana of residents in natural foci in central Italy (1977–1988). Am J Trop Med Hyg 45: 429–434PubMedGoogle Scholar
- 32.Swanepoel R (1987) Viral haemorrhagic fevers in South Africa: history and national strategy. S Afr J Sci 83: 80–88Google Scholar
- 33.Van Tongeren HAE (1981) Imported virus diseases in the Netherlands out of tropical areas 1977–1980 (30 months). Tropenmed Parasit 32: 205Google Scholar