Travel-related vector-borne virus infections in Germany

  • T. F. Schwarz
  • G. Jäger
  • S. Gilch
  • C. Pauli
  • M. Eisenhut
  • H. Nitschko
  • B. Hegenscheid
Part of the Archives of Virology Supplement II book series (ARCHIVES SUPPL, volume 11)


Laboratory diagnosis of imported, vector-borne virus diseases during a 22-month-period in Munich, Germany, is summarized. In 13/317 Germans returning from the Mediterranean with suspected sandfly fever, acute sandfly fever, serotype Toscana, was confirmed serologically: 84.6% of the infections were acquired in Italy. Of 249 German tourists with febrile disease returning from the tropics, acute infection with dengue virus was diagnosed serologically in 26 (10.4%): most infections were acquired in Thailand (57.7%). In a seroepidemiological study of 670 German aid workers who had spent two years in the tropics, 49 (7.3%) were positive for antibodies to dengue, 9 (1.3%) to Chikungunya, and 1 (0.1%) to Sindbis virus. Of 17 Middle Eastern patients with suspected viral haemorrhagic fever, genomic Crimean-Congo haemorrhagic fever virus RNA was amplified in 4 (23.5%) by semi-nested reverse transcriptase polymerase chain reaction, and confirmed by molecular characterization of nucleic acid. With the increase in travel to and from endemic areas, imported vector-borne virus infections are increasingly important in Germany.


Dengue Virus Dengue Fever Haemorrhagic Fever Dengue Haemorrhagic Fever Chikungunya Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag/Wien 1996

Authors and Affiliations

  • T. F. Schwarz
    • 1
  • G. Jäger
    • 1
  • S. Gilch
    • 1
  • C. Pauli
  • M. Eisenhut
    • 1
  • H. Nitschko
    • 1
  • B. Hegenscheid
    • 2
  1. 1.Max von Pettenkofer Institute for Hygiene and Medical MicrobiologyLudwig Maximilians UniversityMunichFederal Republic of Germany
  2. 2.Institute of Tropical MedicineBerlinFederal Republic of Germany

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