Travel-related vector-borne virus infections in Germany

  • T. F. Schwarz
  • G. Jäger
  • S. Gilch
  • C. Pauli
  • M. Eisenhut
  • H. Nitschko
  • B. Hegenscheid
Part of the Archives of Virology Supplement II book series (ARCHIVES SUPPL, volume 11)


Laboratory diagnosis of imported, vector-borne virus diseases during a 22-month-period in Munich, Germany, is summarized. In 13/317 Germans returning from the Mediterranean with suspected sandfly fever, acute sandfly fever, serotype Toscana, was confirmed serologically: 84.6% of the infections were acquired in Italy. Of 249 German tourists with febrile disease returning from the tropics, acute infection with dengue virus was diagnosed serologically in 26 (10.4%): most infections were acquired in Thailand (57.7%). In a seroepidemiological study of 670 German aid workers who had spent two years in the tropics, 49 (7.3%) were positive for antibodies to dengue, 9 (1.3%) to Chikungunya, and 1 (0.1%) to Sindbis virus. Of 17 Middle Eastern patients with suspected viral haemorrhagic fever, genomic Crimean-Congo haemorrhagic fever virus RNA was amplified in 4 (23.5%) by semi-nested reverse transcriptase polymerase chain reaction, and confirmed by molecular characterization of nucleic acid. With the increase in travel to and from endemic areas, imported vector-borne virus infections are increasingly important in Germany.


Dengue Virus Dengue Fever Haemorrhagic Fever Dengue Haemorrhagic Fever Chikungunya Virus 


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Copyright information

© Springer-Verlag/Wien 1996

Authors and Affiliations

  • T. F. Schwarz
    • 1
  • G. Jäger
    • 1
  • S. Gilch
    • 1
  • C. Pauli
  • M. Eisenhut
    • 1
  • H. Nitschko
    • 1
  • B. Hegenscheid
    • 2
  1. 1.Max von Pettenkofer Institute for Hygiene and Medical MicrobiologyLudwig Maximilians UniversityMunichFederal Republic of Germany
  2. 2.Institute of Tropical MedicineBerlinFederal Republic of Germany

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