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Sandfly fever viruses in Italy

  • L. Nicoletti
  • M. G. Ciufolini
  • P. Verani
Conference paper
Part of the Archives of Virology Supplement II book series (ARCHIVES SUPPL, volume 11)

Summary

Two serologically distinct agents, the sandfly fever Sicilian and the sandfly fever Naples viruses, were isolated by Sabin from blood samples taken during an Italian epidemic of febrile illness. Since then, several different viruses have been isolated from sandflies and/or humans in both the Old and New World. Toscana virus, a new virus closely antigenically related to sandfly fever Naples virus, was isolated in 1971 from the sandfly Phlebotomus perniciosus in Italy. Extensive studies on the importance of Toscana virus as a human pathogen demonstrated its association with acute neurologic diseases. A serosurvey for the presence of antibodies to sandfly fever Sicilian, sandfly fever Naples and Toscana viruses indicated that, as in other Mediterranean areas, both sandfly fever Sicilian and sandfly fever Naples viral infections decreased or disappeared after the 1940s in countries performing insecticide-spraying malaria eradication campaigns. In contrast, clinical cases of aseptic meningitis or meningoencephalitis caused by Toscana virus are observed annually in Central Italy during the summer. Toscana virus may be present in other Mediterranean countries where sandflies of the genus Phlebotomus are present.

Keywords

Aseptic Meningitis Bull World Health Organ Transovarial Transmission Toscana Virus Infeetious Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1996

Authors and Affiliations

  • L. Nicoletti
    • 1
  • M. G. Ciufolini
    • 1
  • P. Verani
    • 1
  1. 1.Laboratory of VirologyIstituto Superiore di SanitàRomeItaly

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