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Some Current Concepts of the Chemical Nature of Antigens and Antibodies

  • Chapter
Fortschritte der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles

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Abstract

The basic principles of immunological phenomena have developed to a point where antigen-antibody reactions are an integral part of fundamental biochemistry and an important tool for the physical chemist. This unique position of immunochemistry is due to the work of a large group of investigators during the past fifty years but particularly to Landsteiner for studies of specificity, Heidelberger and colleagues for the development and emphasis of quantitative aspects of immunochemical reactions, and Pauling and his collaborators for the development and investigation of stimulating theoretical concepts. It is somewhat paradoxical that at present these studies have contributed as much if not more to our understanding of the physical nature of proteins than to an understanding of immunity mechanisms. Many of our present concepts may be erroneous or oversimplified but nevertheless furnish a useful basis for investigation of biological phenomena and reactions of proteins.

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Authors and Affiliations

  1. Pasadena, California, USA

    Dan H. Campbell & N. Bulman

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  1. Dan H. Campbell
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  2. N. Bulman
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  1. California Institute of Technology, Pasadena, USA

    L. Zechmeister

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© 1952 Wien · Springer-Verlag

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Campbell, D.H., Bulman, N. (1952). Some Current Concepts of the Chemical Nature of Antigens and Antibodies. In: Zechmeister, L. (eds) Fortschritte der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles. Fortschritte der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles, vol 9. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7169-1_10

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  • DOI: https://doi.org/10.1007/978-3-7091-7169-1_10

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7171-4

  • Online ISBN: 978-3-7091-7169-1

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