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Abstract

In a review on terminal amino acids in peptides and proteins published in 1944 Fox (132) was able to give the position of only one amino acid, phenylalanine, in one protein, insulin, with some degree of certainty [Jensen and Evans (185)]. In the intervening period great advances in our knowledge of amino acid sequences in peptides and proteins have been made. It is now possible to write the complete structural formula for insulin and for many naturally occurring, short-chain polypeptides, two of which, oxytocin and vasopressin, have been synthesised. Much progress has also been made in elucidating the structure of proteins larger than insulin.

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Thompson, E.O.P., Thompson, A.R. (1955). Paper Chromatography in the Study of the Structure of Peptides and Proteins. In: Zechmeister, L. (eds) Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelŀes. Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelŀes, vol 12. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7166-0_6

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