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Abstract

The investigation of Lycopodium alkaloids has a very long history (20). In spite of the fact that the first Lycopodium alkaloid was isolated in the year 1881, and that the number of compounds shown to be present in various Lycopodium spp. has increased steadily since, no progress in the structure elucidation of this interesting class was achieved until the structure of annotinine was deduced in the years 1956–1957 at the University of New Brunswick. A second period of progress came in 1960 when a number of further representatives of the Lycopodium group were clarified. Also, this development was accomplished in several Canadian academic laboratories (McMaster, New Brunswick, Alberta and Ottawa). The structural relationships of the new compounds to each other and to annotinine have lent credence to the theory that the Lycopodium alkaloids are biogenetically derived by cyclization of two straight polyacetate chains (12).

Keywords

Keto Group Asymmetric Center Tetrahedron Letter Hydroxy Ester Oxide Ring 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag in Vienna 1962

Authors and Affiliations

  • Karel Wiesner
    • 1
  1. 1.FrederictonCanada

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