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Structure and Stereochemistry of the Lycopodium Alkaloids

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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progrès dans la Chimie des Substances Organiques Naturelles

Abstract

The investigation of Lycopodium alkaloids has a very long history (20). In spite of the fact that the first Lycopodium alkaloid was isolated in the year 1881, and that the number of compounds shown to be present in various Lycopodium spp. has increased steadily since, no progress in the structure elucidation of this interesting class was achieved until the structure of annotinine was deduced in the years 1956–1957 at the University of New Brunswick. A second period of progress came in 1960 when a number of further representatives of the Lycopodium group were clarified. Also, this development was accomplished in several Canadian academic laboratories (McMaster, New Brunswick, Alberta and Ottawa). The structural relationships of the new compounds to each other and to annotinine have lent credence to the theory that the Lycopodium alkaloids are biogenetically derived by cyclization of two straight polyacetate chains (12).

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Authors and Affiliations

  1. Fredericton, New Brunswick, Canada

    Karel Wiesner

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  1. Karel Wiesner
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  1. California Institute of Technology, Pasadena, USA

    L. Zechmeister

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© 1962 Springer-Verlag in Vienna

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Wiesner, K. (1962). Structure and Stereochemistry of the Lycopodium Alkaloids. In: Zechmeister, L. (eds) Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progrès dans la Chimie des Substances Organiques Naturelles. Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progrès dans la Chimie des Substances Organiques Naturelles, vol 20. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7153-0_7

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  • DOI: https://doi.org/10.1007/978-3-7091-7153-0_7

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7155-4

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