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Zusammenfassung

Die Zeit nach der ersten Synthese eines Peptidwirkstoffes, des Oxytocins, durch du Vigneaud im Jahre 1953, ist mit mannigfaltigen Bemühungen angefüllt, die präparativen Methoden der Peptidchemie zu vervollkommnen. Stimulierend für diese Bemühungen waren die Fortschritte bei der Isolierung und Strukturaufklärung einer Vielzahl von Naturstoffen mit Peptidstruktur und der Wunsch nach eindeutigen und rationellen Synthesen der neuen biologisch aktiven Substanzen. Mit der Zugänglichkeit von Peptidwirkstoffen durch Synthese wurden eingehende pharmakologische und medizinische Untersuchungen ermcht, die viel zum heutigen Verständnis über die physiologische Bedeutung der verschiedensten Polypeptidwirkstoffe beigetragen haben. In einigen Fällen konnten mit synthetischen Produkten sogar therapeutische Anwendungsmchkeiten erschlossen werden.

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Copyright information

© Springer-Verlag / Wien 1968

Authors and Affiliations

  • E. Schröder
    • 1
  • K. Lübke
    • 1
  1. 1.BerlinGermany

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