Chronic Adult Hydrocephalus

  • J. Philippon
  • D. Ancri
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 1)


During the past ten years, adult hydrocephalus has been the subject of extensive work, mainly due to a better understanding of CSF hydrodynamics. At the same time, the description of neurological disorders associated with hydrocephalus and normal CSF pressure, curable by a CSF shunt, has renewed the interest in therapeutics. The best known of these syndromes is the one described by Hakim in 196428, and called “normal pressure” hydrocephalus (NPH).


Subarachnoid Space Ventricular Dilatation None None Obstructive Hydrocephalus Basal Cistern 
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  1. 1.
    Abbott, M., Alksne, J. F., 1968: Transport of intrathecal 125 I-RISA to circulating plasma. A test for communicating hydrocephalus. Neurology (Minneap.) 18–870.Google Scholar
  2. 2.
    Adams, R. D., Fisher, C. M., Hakim, S., Ojemann, R. G., Sweet, W. H., 1965: Symptomatic occult hydrocephalus with “normal” cerebrospinal fluid pressure: a treatable syndrom. New Eng. J. Med. 273, 117–126.CrossRefGoogle Scholar
  3. 3.
    Adams, R. D., Fisher, C. M., Hakim, S., Ojemann, R. G., Sweet, W. H., 1966: Further observations on normal pressure hydrocephalus. Proc. Roy. Soc. Med. 59, 1135–1140.PubMedGoogle Scholar
  4. 4.
    Ancri, D., Fohanno, D., 1972: Données radio-isotopiques qualitatives sur la circulation du liquide céphalo-rachidien. Minerva Neurochirurgica 16, 171–174.Google Scholar
  5. 5.
    Ancri, D., Fohanno, D., 1973: La gammagraphie du LCR dans son segment rachidien. Yie Médicale 23.Google Scholar
  6. 6.
    Appenzeller, O., Salmon, J. H., 1967: Treatment of parenchymatous degeneration of the brain by ventriculo-atrial shunting of CSF. J. Neurosurg. 26, 478–482.PubMedCrossRefGoogle Scholar
  7. 7.
    Atkinson, J. R., Foltz, E. L., 1962: Intraventricular “RISA” as a diagnostic aid in pre and postoperative hydrocephalus. J. Neurosurg. 19, 159–166.PubMedCrossRefGoogle Scholar
  8. 8.
    Bannister, R., Gilford, E., Kocen, R., 1967: Isotope encephalography in the diagnosis of dementia due to communicating hydrocephalus. Lancet 2, 1014–1017.PubMedCrossRefGoogle Scholar
  9. 9.
    Benson, D. F., Le May, M., Patten, D.H., Rubens, A.B., 1970: Diagnosis of normal pressure hydrocephalus. New Eng. J. Med. 283, 609–615.CrossRefGoogle Scholar
  10. 10.
    Bering, E. A., 1955: Choroid plexus and arterial pulsation of cerebrospinal fluid. Arch. Neurol. Psychiat. 73, 165–172.Google Scholar
  11. 11.
    Block, J. D., 1971: Visual impairment in low pressure hydrocephalus. J. Neurol. Neurosurg. Psychiat. 34, 107.PubMedCrossRefGoogle Scholar
  12. 12.
    Curl, F.D., Harbert, J. C., McCullough, D. C., 1972: Quantitative cisternography: an aid to diagnosis. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  13. 13.
    De Blanc, H. J., Natarajan, T. K., James, A. E., Wagner, H. N., 1972: Computer-assisted quantitative cisternography and ventriculography. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  14. 14.
    De Land, F. H., 1971: Cisternography with 169 Yt DTPA. J. Nucl. Med. 12, 683–689.Google Scholar
  15. 15a.
    Di Chiro, G., 1964: New radiographic and isotopie procedures in neurological diagnosis. JAMA 188, 524–529.Google Scholar
  16. 15b.
    Di Chiro, G., 1964: Movement of the cerebrospinal fluid in human beings. Nature (Lond.) 204, 290–291.CrossRefGoogle Scholar
  17. 15c.
    Di Chiro, G., Reames, P. M., Mattews, W. B., Jr., 1964: RISA-ventriculography and RISA cisternography. Neurology (Minneap.) 14, 185–191.Google Scholar
  18. 16.
    Di Chiro, G., 1966: Observation on the circulation of the cerebrospinal fluid. Acta Radiol. (Diagn.) (Stockholm) 5, 988–1002.Google Scholar
  19. 17.
    Fleming, J. F. R., Sheppard, R. H., Turner, V.M. A., 1971: CSF scanning in evaluation of hydrocephalus. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  20. 18.
    Foltz, E. L., Ward, A. A., 1956: Communicating hydrocephalus from subarachnoid bleeding. J. Neurosurg. 13, 546–556.PubMedCrossRefGoogle Scholar
  21. 19.
    Fox, J. L., McCullough, D. C., Green, R. C., 1973: Effects of cerebrospinal fluid shunts on cerebrospinal dynamics. J. Neurol. Neurosurg. Psychiat. 36, 302–312.PubMedCrossRefGoogle Scholar
  22. 20.
    Frigeni, G., Gaini, S. M., Paoletti, P., Villani, R., 1972: La cisternographie iso- topique dans l’étude des altérations de la dynamique du LCR, après traitement neurochirurgical. Minerva Neurochirurgica 16, 186–191.Google Scholar
  23. 21.
    Front, D., Beks, J. W. F., Georganas, Ch. L., Beekhuis, H., Penning, L., 1972: Abnormal patterns of cerebrospinal fluid flow and absorption after head injuries: diagnosis by isotopie cisternography. Neuroradiology 4, 613.PubMedCrossRefGoogle Scholar
  24. 22.
    Galera, R., Greitz, T., 1970: Hydrocephalus in the adult secondary to the rupture of intracranial arterial aneurysms. J. Neurosurg. 32, 634–670.PubMedCrossRefGoogle Scholar
  25. 23.
    Garretson, H. D., Brindle, G. P., 1972: Effects on ventriculo-atrial shunting on CSF dynamics. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  26. 24.
    Geschwind, N., 1968: The mechanism of normal pressure hydrocephalus. J. Neurol. Sci. 7, 481–483.PubMedCrossRefGoogle Scholar
  27. 25.
    Glasauer, F. E., Alker, G. J., Jr., Leslie, E. V., Nicol, C.F., 1968: Isotope cisternography in hydrocephalus with normal pressure. Case report and technical note. J. Neurosurg. 29, 555–561.CrossRefGoogle Scholar
  28. 26a.
    Greitz, T., 1969: An effect of brain distension on cerebral circulation. The Lancet 26, 863–865.CrossRefGoogle Scholar
  29. 26b.
    Greitz, T., 1969: Cerebral blood flow in occult hydrocephalus studies with angiography and the xenon 133 clearance method. Acta Radiol. (Diagn.) (Stockholm) 8, 376–384.Google Scholar
  30. 26c.
    Greitz, T., Ekbom, F., Kukelberg, Breig, A., 1969: Occult hydrocephalus due to ectasia of basilar artery. Acta Radiol. (Diagn.) (Stockholm) 9, 310316.Google Scholar
  31. 26d.
    Greitz, T., Grepe, A. Q. L., Kalmer, M.S., Lopez, J., 1969: Pre and post-operative evaluation of cerebral blood flow in low pressure hydrocephalus. J. Neurosurg. 31, 644–651.PubMedCrossRefGoogle Scholar
  32. 27.
    1970: Encephalography in the diagnosis of convexity block hydrocephalus. Acta Radiol. (Diagn.) (Stockholm) 11, 232–242.Google Scholar
  33. 28.
    Hakim, S., 1964: Algunas observationes sobre la presión del LCR Sindrome hidrocefalico en el adulto con “presión normal” del LCR. Tesis de grado. Universidad Javeriana, Bogota, Columbia.Google Scholar
  34. 29.
    Hakim, S., Adams, R. D., 1965: The special problem of symptomatic hydrocephalus with normal CSF pressure. J. Neurol. Sci. 2, 307–327.PubMedCrossRefGoogle Scholar
  35. 30.
    Hakim, S., 1972: Biomechanics of hydrocephalus. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  36. 31.
    Heck, A., Hameroff, S., Hornick, R., 1971: Chronic listeria monocytogenes meningitis and normotensive hydrocephalus. Neurology 21, 263–271.PubMedGoogle Scholar
  37. 32.
    Heinz, E. R., Davis, D. O., Karp, H. R., 1970: Abnormal isotope cisternography in symptomatic occult hydrocephalus. A correlative isotopic radiological study in 130 subjects. Radiology 95, 109–120.PubMedGoogle Scholar
  38. 33.
    Hill, M. E., Lougheed, W. M., Barnett, H. J., 1967: A treatable form of dementia due to normal pressure hydrocephalus. Canada Med. Ass. J. 97, 1309–1320.Google Scholar
  39. 34.
    Hochwald, G. M., Lux, E. W., Sahar, A., Ransohoff, J., 1972: Experimental hydrocephalus. Changes in cerebrospinal fluid dynamics as a function of time. Arch. Neurol. 26, 120 - 129.PubMedGoogle Scholar
  40. 35.
    Hussey, F., Schanzer, B., Katzman, R., 1970: A simple constant infusion mano- metric test for measurement of CSF absorption; II: Clinical studies. Neurology (Minneap.) 20, 655–680.Google Scholar
  41. 36.
    Illingworth, R. D., Logue, Y., Symon, L., Vemura, K., 1971: The ventricle caval shunt in the treatment of adult hydrocephalus. Result and complication in 101 patients. J. Neurosurg. 35, 681–685.PubMedCrossRefGoogle Scholar
  42. 37.
    Illingworth, R. D., Logue, Y., Symon, L., Vemura, K., 1972: Subdural haematomas after the treatment of chronic hydrocephalus by ventriculo-caval shunt. J. Neurol. Neurosurg. Psychiat. 33, 95–99.CrossRefGoogle Scholar
  43. 38.
    James, A. E., New, P. F. J., Heinz, E. R., Hodges, F. J., De Land, F. H., 1972: A cisternographic classification of hydrocephalus. Am. J. Roentgen. 115, 40–49.Google Scholar
  44. 39.
    Katzman, R., Hussey, F., 1970: A simple constant infusion manometric test for measurement of CSF absorption. I: Rational and method. Neurology (Minneap.) 20, 534–544.Google Scholar
  45. 40.
    Le May, M., New, P. F. J., 1970: Radiological diagnosis of occult normal pressure hydrocephalus. Radiology 96, 347–358.Google Scholar
  46. 41.
    Lerner, M. A., 1968: Everted anterior medullary velum as a pneumographie criterious of hydrocephalus. Clin. Radiol. 88, 334–336.CrossRefGoogle Scholar
  47. 42.
    Lewin, W., 1968: Preliminary observations on external hydrocephalus after severe head injury. Brit. J. Surg. 55, 747–751.PubMedCrossRefGoogle Scholar
  48. 43.
    Lin, J. P., Goodkin, R., Tong, E. C. K, Epstein, F. J., Vinciguerra, E., 1968: Radioiodinated serum albumin (RISA) cisternography in the diagnosis of incisural block and occult hydrocephalus. Radiology 90, 36–41.PubMedGoogle Scholar
  49. 44.
    Lorenzo, A. V., Page, L. K., Watters, G. V., 1970: Relationship between cerebrospinal fluid formation absorption and pressure in human hydrocephalus. Brain 93, 679–692.PubMedCrossRefGoogle Scholar
  50. 45.
    Lundberg, N., 1960: Continuous recording and control of ventricular fluid pressure in neurosurgical practice. Acta Psychiat. Scand. (Suppl. 149 ) 36, 1–193.Google Scholar
  51. 46.
    Lying-Tunnel, IL, Bergqvist, D., Bohmar, G., Malmlund, H. O., Marions, O., Sôderborg, B., 1970: Studies in presenile dementia. Acta Neurol. Scand. (Suppl. 43 ) 46, 90–92.Google Scholar
  52. 47.
    McCullough, D. C., Harbert, J. C., di Chiro, G., Ommaya, A. K., 1970: Prognosis criteria for CSF shunting from cisternography in communicating hydrocephalus. Neurology (Minneap.) 20, 594–598.Google Scholar
  53. 48.
    McHugh, P. R., Goodell, H., 1966: Hydrocephalic dementia: differential diagnosis, psychometric tests and responses to treatment. Neurology (Minneap.) 16, 635–649.Google Scholar
  54. 49.
    Martins, A. N., 1973: Resistance to drainage of cerebrospinal fluid: clinical measurement and significance. J. Neurol. Neurosurg. Psychiat. 36, 313–318.PubMedCrossRefGoogle Scholar
  55. 50.
    Nelson, J. R., Goodman, S. J., 1971: An evaluation of the cerebrospinal fluid infusion test for hydrocephalus. Neurology (Minneap.) 21, 1037–1053.Google Scholar
  56. 51.
    Ojemann, R. G., Fisher, C. M., Adams, R. D., Sweet, W. M., New, P. F. J., 1969: Further experience with the syndrome of “normal” pressure hydrocephalus. J. Neurosurg. 31, 279–294.PubMedCrossRefGoogle Scholar
  57. 52.
    Ojemann, R. G., Fisher, C. M., Adams, R. D., Sweet, W. M., New, P. F. J., 1971: Normal pressure hydrocephalus. Clin. Neurosurg. 18, 337–370.PubMedGoogle Scholar
  58. 53.
    Ommaya, A. R., Mets, M., Post, K. D., 1972: Observations on the mechanics of hydrocephalus. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  59. 54.
    Patten, H. D., Benson, D. F., 1968: Diagnosis of normal pressure hydrocephalus by CSF iodine 131 RISA scanning. J. Nucl. Med. 9, 457–461.PubMedGoogle Scholar
  60. 55.
    Pertuiset, B., Houtteville, J. P., George, B., Margent, P., 1972: Dilatation ventri- ulaire précoce et hydrocéphalies consécutives à la rupture d’anévrismes artériels sus-tentoriels. Neurochirurgia (Stuttgart) 15, 113–126.Google Scholar
  61. 56.
    Philippon, J., Ancri, D., Pertuiset, B., 1971: Hydrocéphalie à pression normale. (Enregistrement de la pression, étude radiologique, transit isotopique.) Rev. Neurol. 125, 347–358.PubMedGoogle Scholar
  62. 57.
    Philippon, J., Ancri, D., Pertuiset, B., George, B., Metzger, J., 1974: Variations of intraventricular pressure during pneumoencephalography. J. Neurosurg. 40 101–106.Google Scholar
  63. 58.
    Ricou, Ph., 1972: Contribution à l’étude de l’hydrocephalie à pression normale. Thesis, Faculty of Medicine of Paris.Google Scholar
  64. 59.
    Rovit, R. L., Schechter, M. W., Ortega, B., Brinker, R., 1972: Progressive ventricular dilatation following pneumoencephalography. A radiological sign of occult hydrocephalus. J. Neurosurg. 36, 50–59.PubMedCrossRefGoogle Scholar
  65. 60.
    Sahar, A., Hochwald, G. M., Sadik, A. R., Ransohoff, J., 1969: Alternate pathway for CSF absorption in animals with experimental obstructive hydrocephalus. Exp. Neurol. 25, 200–206.PubMedCrossRefGoogle Scholar
  66. 61.
    Ransohoff, J., 1970: Experimental hydrocephalus CSF formation and ventricular size as a function of intraventricular pressure. J. Neurol. Sci. 11, 81–91.CrossRefGoogle Scholar
  67. 62.
    Salmon, J. H., 1972: Adult hydrocephalus. Evaluation of shunt therapy in 80 patients. J. Neurosurg. 37, 423–428.PubMedCrossRefGoogle Scholar
  68. 63.
    Samuelson, S., Long, D. M., Chou, S. N., 1972: Subdural hematoma’ as a complication of shunting procedure for normal pressure hydrocephalus. J. Neurosurg. 37, 548–551.PubMedCrossRefGoogle Scholar
  69. 64.
    Sjaastab, O., Skalpe, I. O., Engeset, A., 1969: The width of the temporal horn in the differential diagnosis between pressure hydrocephalus and hydrocephalus ex vacuo. Neurology (Minneap.) 19, 1087–1093.Google Scholar
  70. 65.
    Staab, E. V., Allen, J. H., Young, A. B., Soper, B. A., Meachen, W., 1972: 131 I-HSA cisternograms and pneumoencephalograms in evaluation of hydrocephalus. In Cisternography and Hydrocephalus. A symposium, J. C. Harbert (Ed.). Springfield, Ill.: Ch. C Thomas.Google Scholar
  71. 66.
    Stein, B. M., Tenner, M. S., Fraser, A. R., 1972: Hydrocephalus following removal of cerebellar astrocytomas in children. J. Neurosurg. 36, 763–768.PubMedCrossRefGoogle Scholar
  72. 67.
    Symon, L., Dorsch, N. W. C., Stephens, R. J., 1972: Long term measurement of extradural pressure in “low pressure hydrocephalus”. In Intracranial Pressure, M. Brock and H. Dietz (Eds.). Berlin-Heidelberg-New York: Springer.Google Scholar
  73. 68.
    Tator, C. H., Fleming, J. F. R., Sheppard, R. H., Turner, V. M. A., 1968: Radioisotopic test for communicating hydrocephalus. J. Neurosurg. 28, 327–340.PubMedCrossRefGoogle Scholar
  74. 69.
    Taveras, J. M., 1968: Low-pressure hydrocephalus. In Neuro-ophthalmology, J. L. Smith (Ed.), 293–309.Google Scholar
  75. 70.
    Weller, R. O., Wisniewski, H., Shulman, K., Terry, D., 1971: Experimental hydrocephalus in young dogs. Histological and ultras true tural study of the brain tissue damage. J. Neuropath. Exp. Neurology 30, 613–626.CrossRefGoogle Scholar
  76. 71.
    Wolinsky, J., Barnes, B., Margolis, Th., 1972: Experience with the spinal infusion test in suspected normal pressure hydrocephalus. Neurology (Minneap.) 22, 402.Google Scholar

Copyright information

© Springer-Verlag/Wien 1974

Authors and Affiliations

  • J. Philippon
    • 1
  • D. Ancri
    • 1
  1. 1.Neurosurgical Clinic and Department of Nuclear MedicineHôpital de la PitiéParisFrance

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