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Advances and Technical Standards in Neurosurgery pp 75–122Cite as

Profound Arterial Hypotension (MAP ≤50 mm Hg) Induced with Neuroleptanalgesia and Sodium Nitroprusside (Series of 531 Cases). Reference to Vascular Autoregulation Mechanism and Surgery of Vascular Malformations of the Brain

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Part of the book series: Advances and Technical Standards in Neurosurgery ((NEUROSURGERY,volume 8))

Abstract

The concept of the use of arterial hypotension as an adjuvant in neuro-surgery was first proposed by Cushing in 1917: he observed that in the locally anaesthetized patient haemorrhage during operation was followed by arterial vasoconstriction and subsequently a dry operating field. This observation was radically different from that of Bayliss (1902) who had noticed that arterial hypotension in animals under general anaesthesia was followed by dilatation of the arteries of the brain.

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Authors and Affiliations

  1. Clinique Neuro-Chirurgicale, Laboratoire de Médecine Nucléaire, Service d’Anesthésie-Réanimation, Hôpital de la Pitié, Université Paris, Paris, France

    B. Pertuiset, D. Ancri & A. Lienhart

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  1. B. Pertuiset
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  2. D. Ancri
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Editors and Affiliations

  1. Zürich, Switzerland

    H. Krayenbühl  & M. G. Yaşargil  & 

  2. Bruxelles, Belgium

    J. Brihaye

  3. Homburg/Saar, Germany

    F. Loew

  4. London, UK

    V. Logue  & L. Symon  & 

  5. Padova, Italy

    S. Mingrino

  6. Paris, France

    B. Pertuiset

  7. Helsinki, Finland

    H. Troupp

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Pertuiset, B., Ancri, D., Lienhart, A. (1981). Profound Arterial Hypotension (MAP ≤50 mm Hg) Induced with Neuroleptanalgesia and Sodium Nitroprusside (Series of 531 Cases). Reference to Vascular Autoregulation Mechanism and Surgery of Vascular Malformations of the Brain. In: Krayenbühl, H., et al. Advances and Technical Standards in Neurosurgery. Advances and Technical Standards in Neurosurgery, vol 8. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7046-5_2

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