Subdural Empyema

  • B. Williams
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 9)


Subdural empyema (SDE) has always been an uncommon manifestation of intracranial sepsis; when it presents to neurosurgeons in its commonest, spontaneous form it is usually a rapidly advancing disease with a grave outlook. The condition is commonest in the young, and adequate surgery linked to medical care should be capable of producing morbidity free survival; provided that treatment is started sufficiently early and is correctly chosen.


Brain Abscess Frontal Sinus Burr Hole Bone Flap Subdural Space 
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  1. Anagnostopoulos, D. I., Gortvai, P., 1973: Intracranial subdural abscess. Brit. J. Surg. 60, 50–52.Google Scholar
  2. Anderson, F. M., 1947: Subdural empyema secondary to frontal sinusitis. Review of clinical features and report of three cases. Ann. Otol. Rhinol. Laryngol. 56, 5–17.PubMedGoogle Scholar
  3. Van Alphen, H. A. M., Dreissen, J. J. R. 1976: Brain abscess and subdural empyema. Factors influencing mortality and results of various surgical techniques. J. Neurol. Neurosurg. Psychiat. 39, 481–490.PubMedCrossRefGoogle Scholar
  4. Bannister, G., Williams, B., Smith, S., 1981: Treatment of subdural empyema. J. Neurosurg. 55, 82–88.PubMedCrossRefGoogle Scholar
  5. Beeden, A. G., Marsden, C. D., Meadows, J. C., Michael, W. F., 1969: Intracranial complications of middle ear disease and mastoid surgery. J. Neurol. Sci. 9, 261–272.PubMedCrossRefGoogle Scholar
  6. Bell, W. E., McCormick, W. F., 1975: Neurologic infections in children, pp. 47–8. Philadelphia: Saunders.Google Scholar
  7. Bhandari, Y. S., Sarkari, N. B. S., 1970: Subdural empyema. A review of 37 cases. J. Neurosurg. 32, 35–39.PubMedCrossRefGoogle Scholar
  8. Biehl, J. P., 1955: Subdural empyema secondary to acute frontal sinusitis. A neglected but curable emergency complication. J. A. M. A. 158, 721–724.Google Scholar
  9. Borzone, M., Capuzzo, T., Rivano, C., Tortori-Donati, P., 1980: Subdural empyema: fourteen cases surgically treated. Surg. Neurol. 13, 449–452.Google Scholar
  10. Botterell, E. H., Drake, C. G., 1952: Localised encephalitis, brain abscess and subdural empyema. J. Neurosurg. 9, 348–366.Google Scholar
  11. Coonrod, J. D., Dans, P. E., 1972: Subdural empyema. Amer. J. Med. 53, 85–91.CrossRefGoogle Scholar
  12. Courville, C. B., 1944: Subdural empyema secondary to purulent frontal sinusitis. A clinicopathological study of forty-two cases verified at autopsy. Arch. Otolaryngol. 39, 211–230.Google Scholar
  13. Cowie, R., Williams, B., 1982: Morbidity after subdural empyema. In preparation.Google Scholar
  14. Delgado-Escueta, A. V., Wasterlain, C., Treiman, D. M., Porter, R. J., 1982: Management of status epilepticus. N. Eng. J. Med. 306, 1337–1340.CrossRefGoogle Scholar
  15. Van Dellen, J. R., Boles, D. M., Van Den Heever, C. M., 1977: Interhemispheric subdural empyema. S. Afr. Med. J. 52, 266–269.PubMedGoogle Scholar
  16. Despert, F., Santini, J. J., Ployet, M. J., Chantepie, A., Fauchier, Cl., Combe, P., 1981: L’empyème sous-durai: Une complication rare des infections O. R. L. chez l’enfant. Ann. Paediat. 28,591–595.Google Scholar
  17. Dumville, A. W., 1858: Remarks in trephining the skull. Illustrated by a case. Brit. Med. J. 2, 743.Google Scholar
  18. Farmer, T. W., Wise, G. R., 1973: Subdural empyema in infants, children and adults. Neurology 23, 254–261.PubMedGoogle Scholar
  19. Galbraith, J. G., Barr, V. W., 1974: Epidural abscess and subdural empyema, In: Infectious Diseases of the Central Nervous System. Advances in Neurology, Vol. 6 (Thompson, R. A., Green, J. R., eds.), pp.257 267. New York: Raven Press.Google Scholar
  20. Gardner, W. J., 1933: Subdural abscess in relation to sterile purulent leptomeningitis. Ohio State Med. J. 29, 235–238.Google Scholar
  21. Garfield, J., 1969: Management of supratentorial intracranial abscess: a review of 200 cases. Brit. Med. J. 2, 7–11.PubMedCrossRefGoogle Scholar
  22. Genest, A. S., Bingham, W. G., Hamilton, R. D., 1963: Bilateral subdural empyema. Report of case with arteriograms. J. Neurosurg. 20, 524–526.PubMedCrossRefGoogle Scholar
  23. Glass, R. L., 1947: Osteoplastic flap method in treatment of subdural abscess. J. Neurosurg. 4, 391–393.PubMedCrossRefGoogle Scholar
  24. Griffith, H. B., 1968: Factors in the mortality of cerebellar abscess. J. Neurol. Neurosurg. Psychiat. 31, 89.Google Scholar
  25. Gross, S. W., 1873: An examination of the causes, diagnosis and operative treatment of compression of the brain, as met with in Army practice. Amer. J. Med. Sei. 66, 40–74.CrossRefGoogle Scholar
  26. Gross, S. W., 1946: Osteomyelitis of the frontal bone and subdural empyema with recovery. Amer. J. Surg. 71, 828–831.CrossRefGoogle Scholar
  27. Gurdjian, E. S., Thomas, L. M., 1969: Surgical treatment of cranial and intracranial suppuration. Springfield: Thomas.Google Scholar
  28. Gurdjian, E. S., Thomas, L. M. Webster, J. E., 1948: Modern surgical treatment of acute subdural abscess. Arch. Surg. 57, 411–426.PubMedGoogle Scholar
  29. Hankinson, J., Amador, L. V., 1956: Infected subdural effusions. Brit. Med. J. 11, 122–126.CrossRefGoogle Scholar
  30. Hatanaka, M., Ishii, M., Oda, N., Iwabuchi, T., 1981: Multiple subdural abscess including one in the interhemisphere. No Shinkei Geka 9, 1053–1058.PubMedGoogle Scholar
  31. Hilton, C. M., 1981: Twelve year review of intracranial abscesses. Personal communication.Google Scholar
  32. Hitchcock, E., Andreadis, A., 1964: Subdural empyema: a review of 29 cases. J. Neurol. Neurosurg. Psychiat. 27, 422–434.PubMedCrossRefGoogle Scholar
  33. Hockley, A. D., 1982: Personal communication.Google Scholar
  34. Hollin, S. A., Hayashi, H., Gross, S. W., 1967: Intracranial abscesses of odontogenic origin. Oral Surg. 23, 277–293.PubMedCrossRefGoogle Scholar
  35. Jacobson, S. A., Kane, C. A., 1954: Purulent subdural collection. Neurology 4, 558–562.PubMedGoogle Scholar
  36. Jefferson, G., 1947: The surgery of intracranial abscess. In: Modern Operative Surgery (Turner, G. G., ed.), pp. 1266–1273. London: Cassell.Google Scholar
  37. Joubert, M. J., Stephanov, S., 1977: Computerized tomography and surgical treatment in intracranial suppuration. Report of 30 consecutive unselected cases of brain abscess and subdural empyema. J. Neurosurg. 47, 73–78.PubMedCrossRefGoogle Scholar
  38. Kalbag, R. M., Woolf, A. L., 1967: Cerebral venous thrombosis. London-New York-Toronto: Oxford U. P.Google Scholar
  39. Kaufman, D. M., Miller, M. H., Steigbigel, N. H., 1975: Subdural empyema; analysis of 17 recent cases and review of the literature. Medicine 54, 485–498.PubMedCrossRefGoogle Scholar
  40. Keith, W. S., 1949: Subdural empyema. J. Neurosurg. 6, 127–139.PubMedCrossRefGoogle Scholar
  41. Kiser, J. L., Kendig, J. H., 1963: Intracranial suppuration. A review of 139 consecutive cases with electron-microscopic observations on three. J. Neurosurg. 20, 494–511.PubMedCrossRefGoogle Scholar
  42. Klastersky, J.. Kahan-Coppens, L., Brihaye, J., 1979: Infections in neurosurgery. In: Advances and Technical Standards in Neurosurgery, Vol. 6 (Krayenbühl, H., et al. eds.), pp. 39–54. Wien-New York: Springer.Google Scholar
  43. Kubik, C. S., Adams. R. D., 1943: Subdural empyema. Brain 68, 18–42.CrossRefGoogle Scholar
  44. La Peyronie, F. G. De, 1744: Hist. dé L’Acad. Roy. des Sciences. Sabatier, Médecine Opératoire, p. 212.Google Scholar
  45. Le Beau, J., 1949: Traitement chirurgical de l’empyème sous-durai et sous-arachnoidien. Rev. Neurol. 81, 828–851.Google Scholar
  46. Le Beau, J. Creissard, P., Harispe, L., Redondo, A., 1973: Surgical treatment of brain abscess and subdural empyema. J. Neurosurg. 38, 198–203.Google Scholar
  47. List, C. F., 1950: Interhemispheral subdural suppuration. J. Neurosurg. 7, 313–324.PubMedCrossRefGoogle Scholar
  48. List, C. F. 1955: Diagnosis and treatment of acute subdural empyema. Neurology 5, 663–670.PubMedGoogle Scholar
  49. Luken, M. G. III., Whelan, M. A., 1980: Recent diagnostic experience with subdural empyema. J. Neurosurg. 52, 764–771.PubMedCrossRefGoogle Scholar
  50. Macewen, W., 1893: Pyogenic diseases of the brain and spinal cord. Glasgow: McLehose.Google Scholar
  51. McLaurin, R. L., 1969: Subdural infection. In: Surgical treatment of cranial and intracranial suppuration (Gurdjian, E. S., Thomas, L. M., eds.), pp. 73–88. Springfield: Thomas.Google Scholar
  52. Milhorat, T. H., 1978: Peadiatric Neurosurgery. Philadelphia: Davis.Google Scholar
  53. Mincy, J. E., Peck, F. C. Jr., 1966: Actinomycotic subdural empyema. Survival following surgical draining and antibiotic treatment. N. Y. State J. Med. 66, 2155–2157.PubMedGoogle Scholar
  54. Murphy, J. P., Wilkes, J. D., 1968: Subdural abscess diagnosed by brain scanning. South Med. J. 61, 564–611.PubMedCrossRefGoogle Scholar
  55. Niebeling, H. G., 1959: Subdural empyema. Neurochirurgia 2, 47–54.PubMedGoogle Scholar
  56. Northfield, D. W. C., 1973: The surgery of the central nervous system. Oxford: Blackwell.Google Scholar
  57. Osgood, C. P., Dujovny, M., Holm, E., Postic, B., 1975: Delayed post-traumatic subdural empyema.. J. Trauma 15, 916–921.PubMedCrossRefGoogle Scholar
  58. Pelc, S., 1976: Subdural empyema. Acta Univ. Carol. (Med. Monogr.) 75, 174–175.Google Scholar
  59. Pool, J. L., Potanos, J. N., Krueger, E. G., 1962: Osteomas and rnucocoeles of the frontal paranasal sinuses. J. Neurosurg. 19, 130–135.PubMedCrossRefGoogle Scholar
  60. Post, E. M., Modesti, L. M., 1981: “Subacute” post operative subdural empyema. J. Neurosurg. 55, 761–765.PubMedCrossRefGoogle Scholar
  61. Purdom, D. R., Salmon, M. V., Williams, B., 1976: False positive immuno-fluorescence test for herpes simplex in tuberculous meningitis. Lancet 1, 1235–1236.CrossRefGoogle Scholar
  62. Reynaudin, J. W., Frazee, J., 1980: Subdural empyema importance of early diagnosis. Neurosurgery 7, 477–479.CrossRefGoogle Scholar
  63. Schiller, F., Cairns, H., Russell, D. S., 1948: Treatment of purulent pachymeningitis and subdural suppuration with special reference to penicillin. J. Neurol. Neurosurg. Psychiat. 11, 143–182.PubMedCrossRefGoogle Scholar
  64. Stephanov, S., Joubert, M. J., Welchman, J. M., 1979: Combined convexity and parafalx subdural empyema. Surg. Neurol. 11, 147–151.Google Scholar
  65. Stephens, J., Welch, K., 1956: Subdural abscess with retinal thrombophlebitis. Neurology 6, 889–890.Google Scholar
  66. Stern, W. E., Boldrey, E., 1952: Subdural purulent collections. Surg. Gynec. Obstet. 95, 623–630.Google Scholar
  67. Swaiman, K. F., Gold, L. H. A., 1977: An unusual computed tomographie appearance of a subdural empyema. J. Pediatr. 91, 945–947.PubMedCrossRefGoogle Scholar
  68. Torres, H., Yarzagaray, L., West, C., 1970: Subdural empyema, angiographie and clinic considerations. Neurochirurgia 13, 201–210.PubMedGoogle Scholar
  69. Tovi, F., Sidi, Z., Cohen, A., Tribron, P., 1980: Subdural empyema complicating acute paranasal sinusitis. Harefuah. 99, 371–373.PubMedGoogle Scholar
  70. Verdura, J., White, R. J., Resnikoff, S., et al. 1975: Interhemispheric subdural empyema; angiographie diagnosis and surgical treatment. Surg. Neurol. 3, 89–92.Google Scholar
  71. Watson, P. H., 1870: Case of intracranial abscess following injury successfully treated by trephining. Edinb. Med. J. 16, 43.Google Scholar
  72. Weinman, D., Samarasinghe, H. H. R., 1972: Subdural empyema. Aust. NZ. J. Surg. 41, 324–330.Google Scholar
  73. Whittam, D. E., Pickard, B. H., Wilson, T. D. H., 1968: Brain abscess and otitis media. Acta Otorhinolary ngol. Belg. 23, 375–383.Google Scholar
  74. Williams, B., 1981: Subdural empyema. Hospital Update 8, 111–126.Google Scholar
  75. Williams, B., 1982: The neurosurgery of oto-rhinological sepsis. Clin. Otolaryngol., in press.Google Scholar
  76. Wood, P. H., 1952: Diffuse subdural suppuration. J. Laryngol. Otol. 66, 496--515.PubMedGoogle Scholar
  77. Woodhall, B., 1967: Osteomyelitis and epi-, extra, and subdural abscesses. Clin. Neurosurg. 14, 239–255.Google Scholar
  78. Wright, R. L., 1969: Septic complications of intracranial surgery. In: Surgical treatment of cranial and intracranial suppuration (Gurdjian, E. S., Thomas, L. M., eds.), pp. 93–112. Springfield: Thomas.Google Scholar
  79. Yoshikawa, T. T., Chow, A. W., Guze, L. B., 1975: Role of anaerobic bacteria in subdural empyema. Report of four cases and review of 327 cases from the English literature. Amer. J. Med. 58, 99–104.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag/Wien 1982

Authors and Affiliations

  • B. Williams
    • 1
  1. 1.The Midland Centre for Neurosurgery, NeurologySmethwick, WarleyGreat Britain

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