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Applications of Positron Emission Tomography to Neurosurgery

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Advances and Technical Standards in Neurosurgery

Part of the book series: Advances and Technical Standards in Neurosurgery ((NEUROSURGERY,volume 10))

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Abstract

The introduction a decade ago of X-ray computerised tomography has proved a boon to both patient and neurosurgeon alike. The importance of this advance is apparent from the number of CT scanners installed in centres around the world, the huge literature that has accumulated over their application and use, and the recent award of a Nobel Prize to Hounsfield.

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References

  1. Phelps, M. E., Mazziotta, J. C., Huang, S. C., 1982: Study of cerebral function with positron computed tomography. J. Cereb. Blood Flow Metabol. 2, 113–162.

    Article  CAS  Google Scholar 

  2. Phelps, M. E., Hoffman, E. J., Mullani, N. A., Ter-Pogossian, M. M., 1975: Application of annihilation coincidence detection to transaxial reconstruction tomography. J. Nucl. Med. 16, 210–223.

    PubMed  CAS  Google Scholar 

  3. Muehllehner, G., Colsher, J. O., 1982: Positron emission tomography: instrumentation. In: Computed Emission Tomography (Ell, P. J., Holman, B. L., eds.), pp.3-41. Oxford University Press.

    Google Scholar 

  4. Reivich, M., Jehle, J., Sokoloff, L., Kety, S. S., 1969: Measurement of regional cerebral blood flow with antipyrine-14C in awake cats. J. Appl. Phys. 27, 296–300.

    CAS  Google Scholar 

  5. Sokoloff, L., 1981: Localization of functional activity in the central nervous system by measurement of glucose utilization with radioactive deoxyglucose. J. Cereb. Blood Flow Metabol. 1, 7–36.

    Article  CAS  Google Scholar 

  6. Yamamoto, Y. L., Thompson, C. J., Meyer, E., Robertson, J. S., Feindel, W., 1977: Dynamic positron emission tomography for study of cerebral haemodynamics in cross section of the head using position-emitting 68Ga-EDTA and 77Kr. J. Comput. Assist. Tomogr. 1, 43–56.

    Article  PubMed  CAS  Google Scholar 

  7. Yen, C.-K., Yano, Y., Budinger, T. F., Friedland, R. P., Derenzo, S. E., Huesman, R. H., O’Brien, H. A., 1982: Brain tumour evaluation using Rb-82 and positron emission tomography. J. Nucl. Med. 23, 532–537.

    PubMed  CAS  Google Scholar 

  8. Frackowiak, R. S. J., Lenzi, G. L., Jones, T., Heather, J. D., 1980: Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: theory, procedure, and normal values. J. Comput. Assist. Tomogr. 4, 727–736.

    Article  PubMed  CAS  Google Scholar 

  9. Lammertsma, A. A., Jones, T., Frackowiak, R. S. J., Lenzi, G. L., 1981: A theoretical study of the steady-state model for measuring regional cerebral blood flow and oxygen utilisation using oxygen-15. J. Comput. Assist. Tomogr. 5, 544–550.

    Article  PubMed  CAS  Google Scholar 

  10. Raichle, M. E., Markham, J., Larson, K., Grubb, R. L., Welch, M. J., 1981: Measurement of local cerebral blood flow in man with positron emission tomography. J. Cereb. Blood Flow Metabol. 1(Suppl. 1), S19–S20.

    Google Scholar 

  11. Raichle, M. E., Larson, K. B., Markham, J., Depresseux, J.-C., Grubb, R. L., Ter-Pogossian, M. M., 1981: Measurement of regional oxygen consumption by positron emission tomography. J. Cereb. Blood Flow Metabol. 1(Suppl. 1), S7–S8.

    Google Scholar 

  12. Phelps, M. E., Huang, S. C., Hoffman, E. J., Selin, C., Sokoloff, L., Kuhl, D. E., 1979: Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18) 2-fluoro-2-deoxy-D-glucose: validation of method. Ann. Neurol. 6, 371–388.

    Article  PubMed  CAS  Google Scholar 

  13. Sokoloff, L., Reivich, M., Kennedy, C., des Rosiers, M. H., Patlak, C. S., Pettigrew, K. D., Sakurada, O., Shinohara, M., 1977: The (14C) deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897–916.

    Article  PubMed  CAS  Google Scholar 

  14. Vyska, K., Freundlieb, C., Hvck, A., Becker, V., Feinendegen, L. E., Kloster, G., Stöcklin, G., Traupe, H., Heiss, W.-D., 1981: The assessment of glucose transport across the blood brain barrier in man by the use of 3-(11C)-methyl-D-glucose. J. Cereb. Blood Flow Metabol. 1(Suppl. 1), S42–S43.

    Google Scholar 

  15. Phelps, M. E., Huang, S. C., Hoffman, E. J., Kuhl, D. E., 1978: Validation of tomographic measurement of cerebral blood volume with C-11 labelled carboxyhaemoglobin. J. Nucl. Med. 20, 328–334.

    Google Scholar 

  16. Bustany, P., Sargent, T., Saudubray, J. M., Henry, J. F., Comar, D., 1981: Regional human brain uptake and protein incorporation of 11C-L-methionine studied in vivo with PET. J. Cereb. Blood Flow Metabol. 1(Suppl. 1), S17–S18.

    Google Scholar 

  17. Comar, D., Maziere, M., Gadot, J. M., Berger, G., Soussaline, F., 1979: Visualisation of 11C-flunitrazepan displacement in the brain of the live baboon. Nature 280, 329–331.

    Article  PubMed  CAS  Google Scholar 

  18. Baron, J. C., Roeda, D., Munari, C., Crouzel, C., Stoffels, C., Chodkiewicz, J. P., Comar, D., 1982: Brain regional pharmaco-kinetics of 11C-diphenylhyantoin: positron emission tomography in man. Nuclear Medicine and Biology, Vol.11 (Raynaud, C., ed.), pp. 1748–1751. Oxford: Pergamon Press.

    Google Scholar 

  19. Diksic, M., Farrokhzad, S., Yamamoto, L., Feindel, W., 1982: Labeling of BCNU with 11C and 13N and its in vivo pharmacokinetics study with PET. Nuclear Medicine and Biology, Vol.11 (Raynaud, C., ed.), pp.2285–2286. Oxford: Pergamon Press.

    Google Scholar 

  20. Hübner, K. F., Purvis, J. T., Mahaley, S. M., Robertson, J. T., Rogers, S., Gibbs, W. D., King, P., Partain, C. L., 1982: Brain tumour imaging by positron emission computed tomography using 11C-labelled amino acids. J. Comput. Assist. Tomogr. 6, 544–550.

    Article  PubMed  Google Scholar 

  21. Fukuda, H., Matsuzawa, T., Abe, Y., Endo, S., Yamada, K., Kubota, K., Hatazawa, J., Sato, T., Ito, J., Takahashi, H., Iwata, R., Ido, T., 1982: Cancer detection by F-18 fluorinated glucose analogs. Nuclear Medicine and Biology, Vol.11 (Raynaud, C., ed.), pp. 1996–1999. Oxford: Pergamon Press.

    Google Scholar 

  22. Erickson, K., Bergström, M., Eriksson, L., 1980: Positron emission tomography in the evaluation of subdural haematomas. J. Comput. Assist. Tomogr. 4, 737–745.

    Article  Google Scholar 

  23. Baron, J. C., Comar, D., Bousser, M. G., Soussaline, F., Crouzel, C., Plummer, D., Kellershohn, C., Castaigne, P., 1978: Etude tomographique chez l’homme, du débit sanguine et de la consommation d’oxygène du cerveau par inhalation continue d’oxygène 15. Rev. Neurol. (Paris) 134, 545–556.

    CAS  Google Scholar 

  24. Ackerman, R. H., Correia, J. A., Alpert, N. M., Baron, J. C., Gouliamos, A., Grotta, J. C., Brownell, G. L., Taveras, J. M., 1981: Positron imaging in ischemic stroke disease using compounds labelled with oxygen-15: initial results of clinicophysiologic correlations. Arch. Neurol. 38, 537–543.

    PubMed  CAS  Google Scholar 

  25. Lenzi, G. L., Frackowiak, R. S. J., Jones, T., 1982: Cerebral oxygen metabolism and blood flow in human cerebral ischemic infarction. J. Cereb. Blood Flow Metabol. 2, 321–335.

    Article  CAS  Google Scholar 

  26. Meyer, J. S., 1958: Circulatory changes following occlusion of the middle cerebral artery and their relation to function. J. Neurosurg. 15, 653–673.

    Article  PubMed  CAS  Google Scholar 

  27. Feindel, W., Perot, P., 1965: Red cerebral veins: a report on cerebral tumours and cerebral scars. J. Neurosurg. 22, 315–325.

    Article  PubMed  CAS  Google Scholar 

  28. Wise, R. J. S., Bernardi, S., Frackowiak, R. S. J., Legg, N. J., Jones, T., 1983: Serial observations on the pathophysiology of acute stroke: the transition from ischaemia to infarction as reflected in regional oxygen extraction. Brain 106, 197–222.

    Article  PubMed  Google Scholar 

  29. Barnett, H. J. M., McCormick, C. W., 1980: The collaborative study on STA-MCA anastomosis: a progress report. Surg. Neurol. 13, 409–412.

    PubMed  CAS  Google Scholar 

  30. Lassen, N. A., 1959: Cerebral blood flow and oxygen consumption in man. Physiol. Rev. 39, 183–238.

    PubMed  CAS  Google Scholar 

  31. Grubb, R. L., Phelps, M. E., Raichle, M. E., Ter-Pogossian, M. M., 1973: The effects of arterial blood pressure on the regional cerebral blood volume by X-ray fluorescence. Stroke 4, 390–399.

    Article  PubMed  Google Scholar 

  32. Fog, M., 1938: The relationship between the blood pressure and the tonic regulation of the pial arteries. J. Neurol. Psychiat, 1, 187–197.

    Article  CAS  Google Scholar 

  33. Martin, W. R. W., Grubb, R. L., Raichle, M. E., 1984: Assessment of cerebrovascular reserve in cerebral ischemia with positron emission tomography. Acta neurochir. (Wien) (in press).

    Google Scholar 

  34. Grubb, R. L., Ratcheson, R. A., Raichle, M. E., Kliefoth, A. B., Gado, M. H., 1979: Regional cerebral blood flow and oxygen utilization in superficial temporal-middle cerebral artery anastomosis patients: an exploratory definition of clinical problems. J. Neurosurg. 50, 733–741.

    Article  PubMed  Google Scholar 

  35. Baron, J. C., Bousser, M. G., Rey, A., Guillard, A., Comar, D., Castaigne, P., 1981: Reversal of focal “misery-perfusion syndrome” by extra-intracranial arterial bypass in hemodynamic cerebral ischemia: a case study with 15O position emission tomography. Stroke 12, 454–459.

    Article  PubMed  CAS  Google Scholar 

  36. Weber, G. 1977: Enzymology of cancer cells. X. Engl. J. Med. 296, 486–493 and 441-551.

    CAS  Google Scholar 

  37. Di Chiro, G., de la Paz, R,, Smith, B., Kornblith, P., Sokoloff, L., Brooks, R., Blasberg, R., Cummins, C., Icessler, R., Wolf, A., Fowler, J., London, W., Sever, J., 1981: 18F-2-fluoro-2-deoxyglucose positron emission tomography of human cerebral gliomas. J. Comput. Assist. Tomogr. 5, 937–938.

    Article  Google Scholar 

  38. Ito, M., Lammertsma, A. A., Wise, R. J. S., Bernardi, S., Frackowiak, R. S. J., Heather, J. D., McKenzie, C. G., Thomas, D. G. T., Jones, T., 1982: Measurement of regional cerebral blood flow and oxygen utilisation in patients with cerebral tumours using 15O and positron emission tomography: analytical techniques and preliminary results. Neuroradiology 23, 63–74.

    Article  PubMed  CAS  Google Scholar 

  39. Vaupel, P., 1979: Oxygen supply to malignant tumours. In: Tumour Blood Circulation (Peterson, H.-J., ed.), pp. 143–168. Florida: CRC Press, Inc.

    Google Scholar 

  40. Lammertsma, A. A., Wise, R. J. S., Jones, T., 1983: In vivo measurements of regional cerebral blood flow and blood volume in patients with brain tumours using positron emission tomography. Acta neurochir. (Wien) 69, 5–13.

    Article  CAS  Google Scholar 

  41. Baron, J. C., Bousser, M. G., Comar, D., Castaigne, P., 1980: “Crossed cerebellar diaschisis” in human supratentorial infarction. Ann. Neurol. 8, 128–135.

    Google Scholar 

  42. Lammertsma, A. A., Wise, R. J. S., Jones, T., 1983: Regional cerebral blood flow and oxygen utilization in edema associated with cerebral tumours. In: Recent Progress in the Study and Therapy of Brain Edema (Go, K. G., Baethmann, A. J., eds.). New York-London: Plenum (in press).

    Google Scholar 

  43. Rhodes, C. G., Wise, R. J. S., Hatazawa, J., Frackowiak, R. S. J., Palmer, A. J., Jones, T., 1982: Mismatching between cerebral oxygen and glucose metabolism in patients with cerebral glioma and stroke. Nuclear Medicine and Biology, Vol. II (Raynaud, C., ed.), pp. 2000–2003. Oxford: Pergamon Press.

    Google Scholar 

  44. Warburg, O., 1956: On the origin of cancer cells. Science 123, 309–314.

    Article  PubMed  CAS  Google Scholar 

  45. Diksic, M., Farrokhzad, S., Yamamoto, L., Feindel, W., 1982: Synthesis of “no carrier added” 1,3-bis-(2-chloroethyl) nitrosurea (BCNU). J. Nucl. Med. 23, 895–898.

    PubMed  CAS  Google Scholar 

  46. Kuhl, D. E., Engel, J., Phelps, M. E., Selin, C., 1980: Epileptic patterns of local cerebral metabolism and perfusion in humans determined by emission computed tomography of 18FDG and 13NH3. Ann. Neurol. 8, 348–360.

    Article  PubMed  CAS  Google Scholar 

  47. Engel, J., Rausch, R., Lieb, J. P., Kuhl, D. E., Crandall, P. H., 1981: Correlation of criteria used for localizing epileptic foci in patients considered for surgical therapy of epilepsy. Ann. Neurol. 9, 215–244.

    Article  PubMed  Google Scholar 

  48. Grubb, R, L., Raichle, M. E., Eichung, J. O., Gado, M. H., 1977: Effects of subarachnoid hemorrhage on cerebral blood volume, blood flow and oxygen utilization in humans. J. Neurosurg. 46, 446–453.

    Article  PubMed  Google Scholar 

  49. W. R. W., Baker, R. P., Grubb, R. L., Raichle, M. E., 1984 Cerebral blood volume changes in subarachnoid hemorrhage. Acta neurochir. Wien (in press).

    Google Scholar 

  50. Montgomery, E. B., Grubb, R. L., Raichle, M. E., 1981: Cerebral hemodynamics and metabolism in postoperative cerebral vasospasm and treatment with hypertensive therapy. Ann. Neurol. 9, 502–506.

    Article  PubMed  Google Scholar 

  51. Pickard, J. D., Matheson, M., Patterson, J., Wyper, D., 1980: Prediction of late ischemic complications after cerebral aneurysm surgery by the intraoperative measurement of cerebral blood flow. J. Neurosurg. 53, 305–308.

    Article  PubMed  CAS  Google Scholar 

  52. Farrar, J. K., Gamache, F. W., Ferguson, G. G., Drake, C. G., 1981: Cerebral blood flow (CBF) in profound intraoperative hypotension: correlation with pre-and postoperative measurements. J. Cereb. Blood Flow Metabol. 1(Suppl. 1), S520–S521.

    Google Scholar 

  53. Engel, J., jr., Kuhl, D. E., Phelps, M. E., Mazziotta, J. C., 1982: Interictal cerebral glucose metabolism in partial epilepsy and its relation to EEG changes. Ann. Neurol. 12, 510–517.

    Article  PubMed  Google Scholar 

  54. Engel, J., jr., Brown, J., Kuhl, D. E., Phelps, M. E., Mazziotta, J. C., Crandall, P. H., 1982: Pathological findings underlying focal temporal lobe hypometabolism in partial epilepsy. Ann. Neurol. 12, 518–528.

    Article  PubMed  Google Scholar 

  55. Engel, J., jr., Kuhl, D. E., Phelps, M. E., Crandall, P. H., 1982: Comparative localization of epileptic foci in partial epilepsy by PCT and EEG. Ann. Neurol. 12, 529–537.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. MRC Cyclotron Unit, Hammersmith Hospital, London, UK

    R. J. S. Wise & R. S. J. Frackowiak

  2. III Cattedra di Clinica Neurologica, Università di Roma, Italy

    G. L. Lenzi

  3. National Hospital for Nervous Diseases, London, UK

    R. S. J. Frackowiak

Authors
  1. R. J. S. Wise
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  2. G. L. Lenzi
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  3. R. S. J. Frackowiak
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Editor information

Editors and Affiliations

  1. Zürich, Switzerland

    H. Krayenbühl  & M. G. Yaşargil  & 

  2. Bruxelles, Belgium

    J. Brihaye

  3. Homburg/Saar, Germany

    F. Loew

  4. Padova, Italy

    S. Mingrino

  5. Paris, France

    B. Pertuiset

  6. London, UK

    L. Symon

  7. Helsinki, Finland

    H. Troupp

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© 1983 Springer-Verlag/Wien

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Wise, R.J.S., Lenzi, G.L., Frackowiak, R.S.J. (1983). Applications of Positron Emission Tomography to Neurosurgery. In: Krayenbühl, H., et al. Advances and Technical Standards in Neurosurgery. Advances and Technical Standards in Neurosurgery, vol 10. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7027-4_1

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  • DOI: https://doi.org/10.1007/978-3-7091-7027-4_1

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7029-8

  • Online ISBN: 978-3-7091-7027-4

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