Structure and Function of the Genome
The genome of poliovirus is a single-stranded molecule of RNA of messenger RNA polarity. Since significant amounts of viral RNAs can be conveniently obtained in high purifies, the RNA of poliovirus and other picornaviruses has in the past been used as a model for studying the translation of eukaryotic mRNA (Smith, 1975; Fellner, 1979). With more detailed structural investigations of the viral RNAs, however, it has become clear that they possess some special features, which in part have not been encountered in other eukaryotic mRNAs.
KeywordsPoliovirus Type Poliovirus Genome Sabin Vaccine Strain Poliovirus Protein
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