Composition and Structure of the Virion
studies on the overall virion architecture by electron microscopy and X-ray crystallography
the isolation and characterization of the component parts — the genomic RNA and the different polypeptide building blocks
the determination of the primary structures of RNA and protein
discoveries and partial elucidation of stepwise processes of assembly and disassembly
studies on the type of bonds involved in maintaining capsid integrity
indirect examinations of the relative spatial localization and surface exposure of component parts, and
speculations on the correlation of spatial arrangements and observed functions.
KeywordsCapsid Protein Viral Capsid Antigenic Site Empty Shell Native Virion
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