Dorsal Root Entry Zone (DREZ) Thermocoagulation

  • D. G. T. Thomas
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 15)


Dorsal root entry zone thermocoagulation, that is DREZ lesioning, is useful in the treatment of pain associated with deafferentation. The procedure can control, in many cases, pain caused by avulsion of the brachial plexus, by herpes zoster infection of the spinal dorsal root ganglia, and pain due to traumatic paraplegia. All these conditions are difficult to control by other means including drug treatment, or by surgical methods like sympathectomy, rhizotomy, cordotomy or neurostimulation. The precise anatomical and physiological basis for the success of procedure is not known, but it is probably due to destruction of pain generating centers within the spinal cord as well as to the readjustment of inhibitory and excitatory inputs and the interruption of ascending and descending local reflex pathways.


Dorsal Horn Brachial Plexus Postherpetic Neuralgia Substantia Gelatinosa Herpes Zoster Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag/Wien 1987

Authors and Affiliations

  • D. G. T. Thomas
    • 1
  1. 1.Department of Neurological SurgeryInstitute of Neurology, The National HospitalLondonUK

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