Pain pp 50-63 | Cite as

Evaluation of Antinociceptive, Reinforcing and Aversive Properties of Psychotropic Agents and Analgesics in Animals: Models for Prediction of Their Analgesic Activity and Dependence Liability

  • Friedrich Hoffmeister
Conference paper
Part of the Acta Neurochirurgica Supplementum book series (NEUROCHIRURGICA, volume 38)


Current pharmacotherapy of pain is limited by side effects of analgesics rather than by their lack of pain- alleviating potency. If administered in appropriate doses, the most potent analgesics presently available extinguish, for a brief period, even the most severe states of pain.


Rhesus Monkey Acetylsalicylic Acid Withdrawal Symptom Saline Infusion Progressive Ratio 
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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • Friedrich Hoffmeister
    • 1
  1. 1.EP-FE Leitung, Bayer AGWuppertal 1Federal Republic of Germany

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