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Aktuelle Perspektiven der Biologischen Psychiatrie pp 24–33Cite as

„Nicht-Amyloid“-Hypothesen zur Ätiopathogenese der Demenz vom Alzheimer Typ (DAT)

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Zusammenfassung

Demographische Betrachtungen. Der Altersaufbau der Bevölkerung Deutschlands hat sich im letzten Jahrhundert stark verändert. Nach koordinierten Vorausberechnungen hält dieser Trend an und es werden im Jahr 2030 die am stärksten besetzten Altersjahrgänge im siebten Lebensjahrzehnt zu finden sein (Bundesrat 1984, Sommer 1992). 1989 waren etwa drei Fünftel der Bevölkerung der Bundesrepublik Deutschland zwischen 20 und 60 Jahren alt. Der Anteil der Jüngeren und der Alteren betrug jeweils etwa ein Fünftel. Im Jahre 2030 soll ein Drittel der Bevölkerung 60 Jahre oder älter sein. Die Entwicklung der Altersstruktur zur immer älter werdenden Bevölkerung bedingt weitreichende Konsequenzen für viele Lebensbereiche. Mit Blick auf die Gesundheitsfürsorge ist zu beachten, daß alterskorrelierte chronische Erkrankungen überproportional zunehmen werden. Eine besondere Herausforderung stellen Hirnabbauerkrankungen im Alter dar, die besonders pflegeintensiv sind. Bisher stehen für die Therapie noch keine Strategien und Konzepte zur Verfügung, die als überzeugend gelten können, da ausreichende Erkenntnisse zu Ursachen, Entstehungsbedingungen und verlaufsbestimmenden Faktoren noch nicht vorhanden sind.

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Authors and Affiliations

  1. Klinische Neurochemie, Universitäts-Nervenklinik, Universität Würzburg, Deutschland

    Prof. Dr. Dipl.-Ing. W. Gsell, D. Blum-Degen, Y. Taneli, L. Frölich, M. E. Götz, G. Münch, K. W. Lange, H. Beckmann & P. Riederer

  2. Institut für Pathochemie, Universität Heidelberg, Deutschland

    S. Hoyer

  3. Institut für Rechtsmedizin, Universität Leipzig, Bundesrepublik Deutschland

    R. Voch

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  1. Prof. Dr. Dipl.-Ing. W. Gsell
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  1. Psychiatrische Klinik, Ludwig-Maximilians-Universität München, Nußbaumstraße 7, D-80336, München, Bundesrepublik Deutschland

    H.-J. Möller

  2. Psychiatrische Klinik, Universität Basel, Wilhelm-Klein-Straße 27, CH-4025, Basel, Schweiz

    F. Müller-Spahn

  3. Bezirkskrankenhaus Augsburg, Dr. Mack Straße 1, D-86156, Augsburg, Bundesrepublik Deutschland

    G. Kurtz

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© 1996 Springer-Verlag/Wien

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Gsell, W. et al. (1996). „Nicht-Amyloid“-Hypothesen zur Ätiopathogenese der Demenz vom Alzheimer Typ (DAT). In: Möller, HJ., Müller-Spahn, F., Kurtz, G. (eds) Aktuelle Perspektiven der Biologischen Psychiatrie. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6889-9_4

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  • DOI: https://doi.org/10.1007/978-3-7091-6889-9_4

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7425-8

  • Online ISBN: 978-3-7091-6889-9

  • eBook Packages: Springer Book Archive

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