Cytokines in schizophrenia. Results from a longitudinal study

  • M. Rothermundt
  • V. Arolt
  • C. Weitzsch
  • D. Eckhoff
  • H. Kirchner
Conference paper
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Several lines of evidence indicate that an immunological dysfunction may contribute to the multifactoral etiology of schizophrenia (Kirch, 1993; Syvälahti, 1994; Wright et al., 1993). One approach to further investigate this dysfunction focuses on the field of cytokines. Cytokines are protein mediators that are produced by leukocytes. There is a complex interaction between the different immunocompetent cells, their products and mediators. Cytokines regulate the differentiation and activation of the immunologically active cells and can be regarded as functional markers of cellular immunity.


Cortisol Level Schizophrenic Patient Immunol Today BioI Psychiatry Immunological Dysfunction 
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Copyright information

© Springer-Verlag/Wien 1997

Authors and Affiliations

  • M. Rothermundt
    • 1
  • V. Arolt
    • 1
  • C. Weitzsch
    • 1
  • D. Eckhoff
    • 2
  • H. Kirchner
    • 2
  1. 1.Department of PsychiatryUniversity of Lübeck School of MedicineLübeckFederal Republic of Germany
  2. 2.Department of Immunology and Transfusion MedicineUniversity of Lübeck School of MedicineLübeckFederal Republic of Germany

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