Advertisement

Analysis of Gene Expression of Human Brain

  • Y. Sun
  • R. H. Yolken
  • Stanley Neuropathology Consortium
Conference paper
Part of the Key Topics in Brain Research book series (KEYTOPICS)

Abstract

Normal cell functions are dictated by well regulated patterns of gene expression. Any insult that causes aberrant gene expression will disturb the homeostasis of a cell as a unit. Therefore, measurement of gene expression and the identification of genes that are abnormally expressed during a disease process may provide a clue to the understanding of the pathogenesis of complex human diseases which involve the interaction of genetic and environmental factors.

Keywords

Differential Display Normal Cell Function Complex Human Disease Aberrant Gene Expression Differential Display Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    O’Callaghan E, Gibson T, Colohan HA, Walshe D, Buckley P, Waddington JR (1991) Season of birth in schizophrenia; evidence for confinement of an excess of a winter births to patients without a family history of mental disorder. Br J Psychiatry 158: 764 – 769PubMedCrossRefGoogle Scholar
  2. [2]
    Yolken RH, Torrey EF (1995) Viruses, schizophrenia and bipolar disorder (review). Clin Microbiol Rev 8: 131 – 145PubMedGoogle Scholar
  3. [3]
    Yolken RH, Torrey EF (1995) Viruses, schizophrenia and bipolar disorder (review). Clin Microbiol Rev 8: 131 – 145PubMedGoogle Scholar
  4. [4]
    Velculescu VE, Zhang L, Vogelstein B, Kinzler KW (1995) Serial analysis of gene expression. Science 270: 484 – 487PubMedCrossRefGoogle Scholar
  5. [5]
    Adams MD, Dubnick M, Kerlavage AR, Moreno R, Kelly JM, Utterback TR, Nagle JW, Fields C, Venter JC (1992) Sequence identification of 2375 human brain genes. Nature 335: 632 – 634CrossRefGoogle Scholar

Copyright information

© Springer-Verlag/Wien 1997

Authors and Affiliations

  • Y. Sun
    • 1
  • R. H. Yolken
    • 1
  • Stanley Neuropathology Consortium
    • 1
  1. 1.The Stanley Neurovirology Laboratory, Department of PediatricsJohns Hopkins University School of MedicineBaltimoreUSA

Personalised recommendations