Update on management and genetics of multiple sclerosis

  • A. Dessa Sadovnick
Part of the Journal of Neural Transmission. Supplementa book series (NEURAL SUPPL, volume 50)


Although the exact etiology of multiple sclerosis (MS) remains uncertain, there is an increasing body of evidence to support the role of genetic factors in MS susceptibility in general and the familial aggregation of MS in particular.

MS management continues to be largely symptom-specific. MS relapses are now frequently treated with IV-methylprednisone. In recent years, MS treatment trials are being conducted throughout the world. Interferon beta-lb has been approved as the first ongoing therapy for relapsing/remitting MS, although some issues/concerns remain to be addressed.

In summary, while much research is still needed, important progress is being made in unravelling the etiology of MS and in developing management protocols which are not symptom- or relapse-specific.


Multiple Sclerosis Multiple Sclerosis Patient Familial Aggregation Multiple Sclerosis Relapse Multiple Sclerosis Society 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Wien 1997

Authors and Affiliations

  • A. Dessa Sadovnick
    • 1
  1. 1.Department of Medical GeneticsUniversity of British ColumbiaVancouverCanada

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