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Future international management of African horse sickness vaccines

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African Horse Sickness

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Summary

Three types of African horse sickness (AHS) vaccine, namely adult mouse brain, modified live vaccine and inactivated viral vaccine (IVV) are reviewed. The results of efficacy trials carried out with each vaccine type highlight the advantages of the IVV. Vaccination with African horse sickness virus serotype 4 IVV, given as 2 separate doses, provided full protection against subsequent, homologous challenge. The absence of any detectable viraemia after challenge would also prevent infection of insect vectors. The advantages of establishing international vaccine banks for AHS are discussed.

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Authors and Affiliations

  1. United States Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratory, Foreign Animal Diseases Diagnostic Laboratory, P.O. Box 848, Greenport, Plum Island, New York, 11944, USA

    Dr. J. A. House

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  1. Dr. J. A. House
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Editors and Affiliations

  1. Pirbright Laboratory, Institute for Animal Health, Pirbright, Woking, Surrey, UK

    Philip S. Mellor , Matthew Baylis , Christopher Hamblin  & Peter P. C. Mertens , ,  & 

  2. Arthropod-borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins, Colorado, USA

    Charles H. Calisher

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© 1998 Springer-Verlag/Wien

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House, J.A. (1998). Future international management of African horse sickness vaccines. In: Mellor, P.S., Baylis, M., Hamblin, C., Mertens, P.P.C., Calisher, C.H. (eds) African Horse Sickness. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6823-3_25

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  • DOI: https://doi.org/10.1007/978-3-7091-6823-3_25

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83132-8

  • Online ISBN: 978-3-7091-6823-3

  • eBook Packages: Springer Book Archive

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