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Zusammenfassung

Die 3 Poliomyelitisviren haben grundlegende Eigenschaften der Enteroviren, die zur Gruppe der Picornaviren gehören (picos, gr. = sehr klein). Sie sind 27–30 µm groß, bestehen aus einem Genom (RNA = Ribonukleinsäure) und einem Eiweißkapsid. Die einsträngige Messenger-RNA besteht aus 7.500 Nukleotiden, jede Einheit des Kapsids besteht aus 4 größeren Proteinen (VP1–4) und einem kleineren Eiweißbaustein (VPg). VP1 ist das immundominante Protein. Serologisch werden die Typen 1–3 unterschieden. Paralytische Erkrankungen werden von Typ I>III>II verursacht.

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© 2002 Springer-Verlag/Wien

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Kollaritsch, H., Wiedermann, G. (2002). Poliomyelitis. In: Kollaritsch, H., Wiedermann, G. (eds) Leitfaden für Schutzimpfungen. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6775-5_10

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  • DOI: https://doi.org/10.1007/978-3-7091-6775-5_10

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