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Antihistaminika

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Pharmakotherapie bronchopulmonaler Erkrankungen

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Zusammenfassung

Antihistaminika sind Pharmaka, die die Effekte des körpereigenen Botenstoffes Histamin, des am längsten bekannten Mediators allergischer Reaktionen unterbinden oder hemmen.

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Literatur

  1. . White MV (1990) The role of histamine in allergic disease. J Allergy Clin Immunol 86: 599 – 605

    Article  PubMed  CAS  Google Scholar 

  2. . Giertz H, Flohe L, Peskar BA, Resch K (1992) Mediatoren der Entzündung und Allergie. Pharmakologie und Toxikologie. In: Forth W, Henschler D, Rummel W, Starke K (eds) Wissenschaftsverlag Mannheim, Leipzig, pp 304 – 317

    Google Scholar 

  3. . Simons FER, Simons KJ (1994) The pharmacology and use of H1 receptor antagonist drugs. N Engl J Med 330 (23): 1663 – 1670

    PubMed  CAS  Google Scholar 

  4. Simons FER (1994) The therapeutic index of newer H2 receptor antagonists. Clin Exp Allergy 24: 707 – 723

    Article  PubMed  CAS  Google Scholar 

  5. Bousquet J, Cambell A, Michel FB (1992) Antiallergic activities of antihistamines. In: Church KM, Rihoux JP (eds) Therapeutic index of antihistamines. Hogrefe & Huber, Lewiston, pp 57 – 96

    Google Scholar 

  6. Simons FER, Simons KJ (1993) In: Middle- town E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW, Busse WW (eds) Allergy principles and practice, 4th ed., vol 1. Mosby Year Book, St. Louis, pp 856 – 892

    Google Scholar 

  7. . Pearce FL (1991) Biological effects of histamine - an overview. Agents Actions 33: 4 – 7

    Article  PubMed  CAS  Google Scholar 

  8. . Dale HH, Laidlaw PP (1910) The physiological action of betaimidazolylethylamine. J Physiol 41: p 318

    PubMed  CAS  Google Scholar 

  9. . Simons FER (1992) Pharmacological characteristics of second generation Ha-blockers. In: Church KM, Rihoux JP (eds) Therapeutic index of antihistamines. Hogrefe & Huber, Lewiston, pp 1 – 56

    Google Scholar 

  10. . Bartosch R, Feldberg W, Nagel E (1932) Das Freiwerden eines histaminahnlichen Stoffes bei der Anaphylaxie des Meerschweinchens. Pfliigers Arch 230, p 129

    Article  CAS  Google Scholar 

  11. Ishizaka T, White JR, Saito H (1987) Secretory mechanismus in mast cells and basophils. In: Kay AB (ed) Allergy and inflammation. Academic Press London, New York, pp 1–16

    Google Scholar 

  12. . Rucklin RE (ed) (1990) Histamine and H2 Antagonists in inflammation and immunodeficiency. Marcel Dekker, New York

    Google Scholar 

  13. . Nash J, Lambert L, Deakin M (1994) Histamine H2-receptor antagonist in peptic ulcer disease. Drugs 47: 862 – 871

    Article  PubMed  CAS  Google Scholar 

  14. . Arrang JM, Garbarg M, Lancelot JC, Lecomte JM et al (1987) Highly potent and selective ligands for histamine H3-receptors. Nature 327: 117 – 123

    Article  PubMed  CAS  Google Scholar 

  15. . Casy AI (1991) Antagonists of H1 receptors of histamine: recent developments. In: Uvnas B (ed) Histamine and histamine antagonists No. 97 of handbook of experimental pharmacology. Springer, Berlin Heidelberg New York Tokyo, pp 549 – 572

    Google Scholar 

  16. . Garrison CJ (1991) Histamine, bradykinin, 5-hydroxytryptamine and their antagonists. In: Gilman AG, Rail ThW, Nies AS and Taylor P (eds) The Pharmacological basis of therapeutics, 8th edn. Pergamon Press, New York, Oxford

    Google Scholar 

  17. . Trzeciakowski JP, Mendelson N, Levi R (1988) Antihistamines. In: Middletown E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW (eds) Allergy principles and practice, vol 1. C.V. Mosby, St. Louis, pp 715 – 738

    Google Scholar 

  18. . Bardin PG, Hogate ST (1994) Antihistamines. In: Page CP, Metzger WJ (eds) Advances in clinical pharamcology; drugs and the lung. Raven Press, New York, pp 257 – 280

    Google Scholar 

  19. . Rote Liste (1998) Arzneimittelverzeichnis des BPI. Bundesverband der Pharmazeutischen Industrie e.V. ECV. Editio Cantor, Aulen- dorf/Württ

    Google Scholar 

  20. . Arzneimittel Kompendium der Schweiz (1999) Morant J, Ruppanner H (eds) Documed, Basel (CD-ROM )

    Google Scholar 

  21. . Drug (1994) Edition - facts and comparisons. A Wolters Kluwer, St. Louis

    Google Scholar 

  22. . Thomson NC, Kerr JW (1980) Effect of inhaled H1 and H2 receptor antagonists in normal and asthmatic subjects. Thorax 35: 420 – 434

    Article  Google Scholar 

  23. . Hodges IG, Milner AD, Stokes GM (1983) Bronchodilator effect of two inhaled receptor antagonists, elemestine and chlorpheniramine, in wheezy school children. Br J Dis Chest 77: 270 – 275

    Article  PubMed  CAS  Google Scholar 

  24. . Phillips MJ, Oilier S, Gould C, Davies RJ (1984) Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma. Thorax 39: 345 – 351

    Article  PubMed  CAS  Google Scholar 

  25. . Simons FER (1989) H1-receptor antagonists: clinical pharmacology and therapeutics. J Allergy Clin Immunology 84: 845 – 861

    Article  CAS  Google Scholar 

  26. . Simons FER, Simons KJ (1991) Second-gene-ration H1-receptor antagonists. Ann Allergy 66: 5 – 21

    PubMed  CAS  Google Scholar 

  27. . Wood-Baker R, Holgate ST (1993) The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma. J Allergy Clin Immunol 91: 1005 – 1014

    Article  PubMed  CAS  Google Scholar 

  28. . Wasserfallen JB, Leuenberger P, Pécoud A (1993) Effect of cetirizine, a new H1 anti-histamine, on the early and late allergic reactions in a bronchial provocation test with allergen. J Allergy Clin Immunol 91: 1189 – 1197

    Article  PubMed  CAS  Google Scholar 

  29. . Redier H, Chanez P, De Vos C, Rifai N, Clauzel AM et al (1992) Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma. J Allergy Clin Immunol 90: 215 – 224

    Article  PubMed  CAS  Google Scholar 

  30. . Wüthrich B, Radielovic P (1978) Zur me- dikamentösen Bronchialasthma-Prophylaxe- Inhibitorischer Effekt einer neuen oral wirk- samen antiana-phylaktischen Substanz auf den histamin-und anstrengungsinduzierten Bronchospasmus. Dtsch Med Wochenschr 103: 1865 – 1869

    Article  PubMed  Google Scholar 

  31. . Girard JP, Lech B, Radielovic P (1992) A double blind study to evaluate the efficacy and tolerability of modified release ketotifen in the treatment of bronchial asthma. Am J Clin Res 1: 37 – 47

    Google Scholar 

  32. . Medici TC, Radielovic P, Morley J (1989) Ketotifen in the prophylaxis of extrinsic bronchial asthma. Chest 96: 1252 – 1257

    Article  PubMed  CAS  Google Scholar 

  33. . Debelic M, Radielovic P, Wüthrich B (1976) Inhibitory effect of antihistamines on bronchial provocation tests. Allergol Immuno-pathol 4: 199 – 200

    Google Scholar 

  34. . Blaye IL, Donatini B, Hall M, Krupp P (1992) Acute ketotifen over-dosage. Drug Safety 7: 387 – 392

    Article  PubMed  Google Scholar 

  35. . Schmutzler W (1997) Histamin als Mediator allergischer Reaktionen. Allergologie 20: 536 – 542

    Google Scholar 

  36. . van Ganse E, Kaufman L, Derde MP et al (1997) Effects of antihistamines in adult asthma: a meta-analysis of clinical trials. Eur Respir J 10: 2216 – 2224

    Article  PubMed  Google Scholar 

  37. . Passalacqua G, Bousquet J, Bachert C, Church MK et al (1996) EAACI Position paper. The clinical safety of H1-receptor antagonists. Allergy 51: 666 – 675

    PubMed  CAS  Google Scholar 

  38. . Ekström T, Osterman K, Zetterström O (1995) Lack of effect of loratadane on moderate to severe asthma. Ann Allergy 75: 287 – 289

    Google Scholar 

  39. . Menardo JL, Horak F, Danzig MR, Czarlevski W (1997) A review of loratadine in the treatment of patients with allergic bronchial asthma. Clin Ther 19: 1278 – 1293

    Article  PubMed  CAS  Google Scholar 

  40. . Malick A, Grant JA (1997) Antihistamies in the treatment of asthma. Allergy 52: 55 – 66

    Article  PubMed  CAS  Google Scholar 

  41. . Corren J (1997) Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol 99: 781 – 786

    Article  Google Scholar 

  42. . Hoshino M, Nakamura Y, Shin Z, Fukushima Y (1997) Effects of ketotifen on symptoms and on bronchial mucosa in patients with atopic asthma. Allergy 52: 814 – 820

    Article  PubMed  CAS  Google Scholar 

  43. . Schatz M, Zeiger RS, Harden K, Hoffman CC, Chilingar L, Pettiti D (1997) The safety of asthma and allergy medications during pregnancy. J Allergy Clin Immunology 100: 301 – 306

    Article  CAS  Google Scholar 

  44. . Nolen TM (1997) Sedative effects of antihista-mines: safety, performance, learning and quolity of life. Clin Ther 19: 39 – 55

    Article  PubMed  CAS  Google Scholar 

  45. . Meltzer EO (1995) The use of anti-H1-drugs in mild asthma. Allergy 50: 41 – 47

    Article  PubMed  CAS  Google Scholar 

  46. . Sale ME, Barbey JT, Woosley RL et al (1994) The electrocardiographic effects of cetirizine in normal subjects. Clin Pharmacol Ther 56: 295 – 301

    Article  PubMed  CAS  Google Scholar 

  47. . Holgate ST (1994) Antihistamines in the treatment of asthma. Clin Rev Allergy 12: 65 – 78

    PubMed  CAS  Google Scholar 

  48. . Busse W (1998) Current research and future needs in allergic rhinitis and asthma. J Allergy Clin Immunol 101: 424 – 426

    Article  Google Scholar 

  49. . Radielovic P, Morley J, Hansel T, Medici TC (1995) Zaditen SRO® permits once-a-daily dosing with superior efficacy in the prophy-laxis of asthma. J Asthma 32: 105 – 115

    Article  PubMed  CAS  Google Scholar 

  50. . Reider N, Zloczower M, Fritsch P, Kofler H (1998) Antihistaminika I Hautarzt 49: 674 – 681

    Article  CAS  Google Scholar 

  51. . Reider N, Zloczower M, Fritsch P, Kofler H (1998) Antihistaminika II Hautarzt 49: 734 – 742

    Article  CAS  Google Scholar 

  52. . Martin E (1998) Nebenwirkungen von Antihi-staminika. Allergologie 21: 545 – 549

    Google Scholar 

  53. . Helbling A (1998) Nahrungsmittelallergie. Praxis 87: 1309 – 1315

    CAS  Google Scholar 

  54. . Lindquist M, Edwards IR (1997) Risk of non-sedating antihistamines. Lancet 349: 1322 – 1329

    Article  PubMed  CAS  Google Scholar 

  55. . Schmutzler W (1998) Kardiotoxische Neben-wirkungen der H1-Antihistaminika. Allergologie 21: 138 – 139

    Google Scholar 

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Authors
  1. P. Radielovic
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  2. T. C. Medici
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  3. B. Wüthrich
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Editor information

Editors and Affiliations

  1. Wilhelminenspital der Stadt Wien, Wien, Österreich

    Friedrich Kummer

  2. Ruhrlandklinik, Essen, Deutschland

    Nikolaus Konietzko

  3. Universitätsspital, Zürich, Schweiz

    Tullio C. Medici

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© 2000 Springer-Verlag/Wien

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Radielovic, P., Medici, T.C., Wüthrich, B. (2000). Antihistaminika. In: Kummer, F., Konietzko, N., Medici, T.C. (eds) Pharmakotherapie bronchopulmonaler Erkrankungen. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6761-8_8

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  • DOI: https://doi.org/10.1007/978-3-7091-6761-8_8

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7404-3

  • Online ISBN: 978-3-7091-6761-8

  • eBook Packages: Springer Book Archive

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