Summary
The purpose of this study is to test the validity of a proposed compliance index, percent change of compliance per mmHg of intracranial pressure (%CC/mmHg), by comparison of values of the index with corresponding experimentally derived values of compliance. The derivation of %CC/mmHg is based on two assumptions: 1) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the sac does not significantly change.
By rapid infusion of 0.2 ml of mock cerebrospinal fluid (CSF) experimental values of compliance (n = 44) were obtained from 10 piglets during monitoring of intracranial pressure (ICP). A strong correlation (r = 0.89, p <.001, n = 44) was obtained between values of %CC/mmHg and corresponding values of experimentally derived compliance (ml/mmHg). The value of the proposed index of compliance, %CC/mmHg, needs to be evaluated in the clinical setting. However, from the view of validation of ICP instrumentation, high values of both mean ICP and mean %CC/mmHg are contradictory and indicative of the occurrence of instrumentation error due to electronic direct current drift.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Avezaat CFF, van Eijndhoven JHM, Wyper DJ (1979) Cerebrospinal fluid pulse pressure and intracranial volume-pressure relationships. J Neurol Neurosurg Psychiatry 42: 687-700
Czosnyka M, Guazzo E, Whitehouse P, Smielewski Z, Kirkpatrick K, Piechnik S, and Pickard JD (1996) Significance of intracranial pressure waveform analysis after head injury. Acta Neurochir(Wien) 138: 531-542
Daley ML, Gallo AE, Mauch W (1986) Analysis of the intracranial pressure pulsation associated with the cardiac cycle. Innovation Et Tech En Biologie Et Medicine 7: 537-544
Daley ML and Leffler CW (1998) Correlation coefficient between ICP and arterial pressure: a gauge of cerebral vascular dilation. Acta Neurochir (Wien) [Suppl] 71: 285-288
Foltz EL, Blanks JP, Yonemura K (1990) CSF pulsatility in hydrocephalus: Respiratory effect on pulse wave slope as an indicator of intracranial compliance. Neurol Res 12: 67-74
Robertson CS, Narayan RK, Contant C, Grossman R, Pahwa R, Caram P, Bray RS, Sherwood AM (1989) Clinical experience with a continuous monitor of intracranial compliance. J Neurosurg 71: 673-680
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer-Verlag
About this paper
Cite this paper
Daley, M.L., Pourcyous, M., Stidham, G., Timmons, S.D., Leffler, C.W. (2002). An Estimated Compliance Index Derived from Intracranial Pressure Recording. In: Czosnyka, M., Pickard, J.D., Kirkpatrick, P.J., Smielewski, P., Hutchinson, P. (eds) Intracranial Pressure and Brain Biochemical Monitoring. Acta Neurochirurgica Supplements, vol 81. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6738-0_48
Download citation
DOI: https://doi.org/10.1007/978-3-7091-6738-0_48
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-7397-8
Online ISBN: 978-3-7091-6738-0
eBook Packages: Springer Book Archive