The neurobiochemical substratum of spasticity is highly complex and remains poorly understood. However, it is possible to throw some light on it using data from functional neuroanatomy and pharmacological studies of antispastic drugs. In this chapter we will look at the neurobiochemistry of control exerted at the segmental (spinal) level, then at those exerted at the supraspinal levels.
KeywordsMotor Neuron Primary Motor Cortex Motor Neuron Peripheral Afferents Renshaw Cell
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