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CSF pharmacokinetic of intrathecal Baclofen administration

  • B. Sallerin-Caute
  • Y. Lazorthes
  • R. Bastide

Abstract

For the achievement of an optimal pharmacotherapy with intrathecal Baclofen, an analysis of the relationships between therapeutic effects and frug concentration in CSF may be valuable, We had previously developed a sensitive method for the measurement of Baclofen concentration in human CSF (Sallerin-Caute et al. 1988). The present pharmacokinetic study was carried out within the framework of a clinical investigation (see chapter by Lazorthes and Verdié).

Keywords

High Performance Liquid Chromatography High Performance Liquid Chromatography Pharmacokinetic Study Clinical Investigation High Performance Liquid Chromatography Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. See pages 115, 116Google Scholar

Copyright information

© Springer-Verlag Wien 1991

Authors and Affiliations

  • B. Sallerin-Caute
    • 1
  • Y. Lazorthes
    • 1
  • R. Bastide
    • 1
  1. 1.Department of NeurosurgeryCentre Hospitalier de RangueilToulouseFrance

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