Abstract
For the achievement of an optimal pharmacotherapy with intrathecal Baclofen, an analysis of the relationships between therapeutic effects and frug concentration in CSF may be valuable, We had previously developed a sensitive method for the measurement of Baclofen concentration in human CSF (Sallerin-Caute et al. 1988). The present pharmacokinetic study was carried out within the framework of a clinical investigation (see chapter by Lazorthes and VerdiƩ).
Keywords
- High Performance Liquid Chromatography
- High Performance Liquid Chromatography
- Pharmacokinetic Study
- Clinical Investigation
- High Performance Liquid Chromatography Analysis
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Ā© 1991 Springer-Verlag Wien
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Sallerin-Caute, B., Lazorthes, Y., Bastide, R. (1991). CSF pharmacokinetic of intrathecal Baclofen administration. In: Sindou, M.P., Abbott, I.R., Keravel, Y. (eds) Neurosurgery for Spasticity. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6708-3_14
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DOI: https://doi.org/10.1007/978-3-7091-6708-3_14
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-7388-6
Online ISBN: 978-3-7091-6708-3
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