Target dimensions in prediction of neuroleptic response: concepts and instruments

  • J. M. Kane
Conference paper


A variety of conceptual and practical issues need to be addressed in the study of neuroleptic response predictors. This paper will attempt to review some major aspects of this topic.


Negative Symptom Target Dimension Neuroleptic Treatment Acute Care Inpatient Negative Symptom Score 


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  1. Kane J, Honigfeld G, Singer J, Meltzer H, and the Clozaril Collaborative Study Group (1988) Clozapine for the treatment-resistant schizophrenic: a double-blind comparison versus chlorpromazine/benztropine. Arch Gen Psychiatry 45:789–796.PubMedCrossRefGoogle Scholar
  2. Kinon BJ, Kane JM, Johns C, Perovich R, Ismi M, Koreen A, Weiden P (1993) Treatment of neuroleptic resistant schizophrenic relapse. Psychopharmacol Bull 29(2):309–314.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Wien 1994

Authors and Affiliations

  • J. M. Kane
    • 1
    • 2
  1. 1.Department of PsychiatryHillside Hospital, Division of Long Island Jewish Medical CenterGlen OaksUSA
  2. 2.Albert Einstein College of MedicineBronxUSA

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